WormBase Tree Display for Gene: WBGene00002992

WBGene00002992 SMap: S_parent: Sequence: CHROMOSOME_IV
  Identity: Version: 2
    Name: CGC_name: lin-3 Person_evidence: WBPerson261
      Sequence_name: F36H1.4
      Molecular_name (27)
      Other_name: let-94
        sli-4 Paper_evidence: WBPaper00028495
          Person_evidence: WBPerson625
        CELE_F36H1.4 Accession_evidence: NDB BX284604
      Public_name: lin-3
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:30 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 05 Oct 2006 10:39:45 WBPerson2970 Name_change: Other_name: sli-4
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: lin
    Reference_allele: WBVar00143992
    Allele (126)
    Legacy_information (3)
    Strain (13)
    RNASeq_FPKM (74)
    GO_annotation (32)
    Ortholog (21)
    Structured_description: Concise_description: lin-3 encodes a member of the EGF family of peptide growth factors that affects induction of vulval development, viability, ovulation, behavioral quiescence after stress, and male spicule development; it acts genetically upstream of its presumptive receptor let-23, and is expressed in multiple locations consistent with it acting as a localized ligand; for example, the anchor cell of the developing gonad, which induces vulval development. Paper_evidence: WBPaper00000496
            WBPaper00001573
            WBPaper00045813
            WBPaper00002043
          Person_evidence: WBPerson625
          Curator_confirmed: WBPerson324
            WBPerson567
          Date_last_updated: 13 Jul 2015 00:00:00
      Automated_description: Enables receptor ligand activity. Involved in several processes, including positive regulation of ovulation; positive regulation of vulval development; and reproductive process. Located in plasma membrane. Expressed in several structures, including excretory canal; germ line; hermaphrodite gonad; rectal epithelial cell; and vulF. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F36H1.4a
      F36H1.4b
      F36H1.4c
      F36H1.4d
      F36H1.4e
      F36H1.4f
      F36H1.4g
      F36H1.4h
    Corresponding_CDS_history: F36H1.4:wp52
    Corresponding_transcript (11)
    Other_sequence: CR09820
      CRC07071_1
      CJC02266_1
    Associated_feature (12)
  Experimental_info: RNAi_result (54)
    Expr_pattern (16)
    Drives_construct (19)
    Construct_product (27)
    Microarray_results: SMD_F36H1.4
      SMD_Y5F2A.1
      193383_at
      A_12_P110041
      A_12_P116897
      A_12_P119738
      A_12_P149955
      A_12_P149956
      A_12_P149957
      Aff_F36H1.4
      GPL13394_WBGene00002992
      GPL13914_F36H1.4
      GPL14144_F36H1.4f_1201-1260_0.926_8_B
      GPL14144_F36H1.4f_1315-1374_0.933_4_A
      GPL14144_F36H1.4f_829-888_0.911_13_C
      GPL19516_CGZ0020051
      GPL19516_CGZ0020052
      GPL19516_CGZ0020053
      GPL19516_CGZ0020054
      GPL19516_CGZ0020055
      GPL19516_CGZ0020056
      GPL19516_CGZ0020057
      GPL19516_CGZ0020058
      GPL19516_CGZ0020059
      GPL21109_F36H1.4a
      GPL21109_F36H1.4b.1
      GPL3518_CE30348
      GPL8304_CE_WBGene00002992_A
      GPL8304_CE_WBGene00002992_B
      GPL8673_F36H1_4aP00571
      GPL8673_F36H1_4aP00771
      GPL8673_F36H1_4aP01215
      GPL8673_F36H1_4bP00565
      GPL8673_F36H1_4bP00765
      GPL8673_F36H1_4bP01209
      GPL8673_F36H1_4cP00571
      GPL8673_F36H1_4cP00726
      GPL8673_F36H1_4cP01170
      GPL8673_F36H1_4dP00565
      GPL8673_F36H1_4dP00701
      GPL8673_F36H1_4dP01287
      GPL9450_F36H1.4b
      cea2.d.24016
      cea2.d.24036
    Expression_cluster (158)
    Interaction (299)
    WBProcess: WBbiopr:00000020
      WBbiopr:00000044
      WBbiopr:00000067
      WBbiopr:00000070
      WBbiopr:00000071
  Map_info: Map: IV Position: 4.82027 Error: 0.004649
    Well_ordered
    Positive: Positive_clone: F36H1 Inferred_automatically: From sequence, transcript, pseudogene data
        PS#001
    Mapping_data: 2_point: 3296
      Multi_point: 117
        382
        383
        603
        678
        774
        1135
        1137
        1276
        1640
      Pos_neg_data (16)
  Reference (361)
  Remark: Updated sequence connections to take account of splice variants. [02/03/28 krb]
  Method: Gene