WormBase Tree Display for Gene: WBGene00000458
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WBGene00000458 | SMap | S_parent | Sequence | CHROMOSOME_X | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | ceh | ||||||
Allele (260) | |||||||
Strain | WBStrain00003219 | ||||||
WBStrain00024200 | |||||||
WBStrain00024201 | |||||||
WBStrain00031536 | |||||||
WBStrain00048942 | |||||||
WBStrain00055073 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (27) | |||||||
Ortholog (38) | |||||||
Paralog (20) | |||||||
Structured_description | Concise_description | ceh-37 encodes one of three C. elegans proteins with an OTX-like homeodomain; however, CEH-37 lacks other domains found in OTX proteins, and the CEH-37 homeodomain is predicted to resemble the Myb domain of telomere-binding proteins; CEH-37 binds the telomeric sequence 'TTAGGC' if it is repeated at least 1.5 times, and is mainly localized to the telomere in vivo; ceh-37 mutants have a weak increase in chromosomal nondisjunction; CEH-37 is involved in specifying some aspects of the AWB olfactory neuron fate, such as expression of an AWB-specific odorant receptor and a LIM-class homeodomain protein, LIM-4; CEH-37 is expressed broadly in the early embryo, while in larvae and adults it is expressed solely in the excretory cell. | Paper_evidence (4) | ||||
Curator_confirmed | WBPerson480 | ||||||
WBPerson1843 | |||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||
Automated_description | Enables DNA binding activity, bending and double-stranded telomeric DNA binding activity. Involved in neuron fate specification; olfactory behavior; and regulation of transcription by RNA polymerase II. Located in chromosome, telomeric region. Expressed in several structures, including ABarpaap; dorsal nerve cord; excretory cell; head muscle; and head neurons. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 7 and cone-rod dystrophy 2. Is an ortholog of human CRX (cone-rod homeobox). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS292 version of WormBase | ||||||
Date_last_updated | 24 Apr 2024 00:00:00 | ||||||
Disease_info | Potential_model | DOID:0110333 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2383) | ||
DOID:0111005 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2383) | ||||
Molecular_info | Corresponding_CDS | C37E2.5a | |||||
C37E2.5b | |||||||
C37E2.5c | |||||||
C37E2.5d | |||||||
Corresponding_transcript | C37E2.5a.1 | ||||||
C37E2.5b.1 | |||||||
C37E2.5c.1 | |||||||
C37E2.5d.1 | |||||||
Other_sequence | ACC33504_1 | ||||||
OOC03311_1 | |||||||
Oden_isotig21898 | |||||||
JI175634.1 | |||||||
PPC21066_1 | |||||||
JI170763.1 | |||||||
ES564168.1 | |||||||
EX559356.1 | |||||||
Associated_feature (20) | |||||||
Transcription_factor | WBTranscriptionFactor000475 | ||||||
Experimental_info | RNAi_result | WBRNAi00107118 | Inferred_automatically | RNAi_primary | |||
WBRNAi00106222 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00090702 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00029643 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00042117 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00011722 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern (14) | |||||||
Drives_construct | WBCnstr00001666 | ||||||
WBCnstr00003694 | |||||||
WBCnstr00010926 | |||||||
WBCnstr00012613 | |||||||
WBCnstr00018499 | |||||||
Construct_product | WBCnstr00010870 | ||||||
WBCnstr00018499 | |||||||
Microarray_results | SMD_C37E2.5 | ||||||
173897_at | |||||||
192014_s_at | |||||||
A_12_P116738 | |||||||
Aff_C37E2.5 | |||||||
GPL13394_WBGene00000458 | |||||||
GPL13914_C37E2.5 | |||||||
GPL14144_C37E2.5_166-225_0.922_18_A | |||||||
GPL14144_C37E2.5_681-740_0.954_5_B | |||||||
GPL14144_C37E2.5_789-848_0.966_1_C | |||||||
GPL19516_CGZ0008072 | |||||||
GPL21109_C37E2.5 | |||||||
GPL3518_CE08624 | |||||||
GPL8304_CE_WBGene00000458_A | |||||||
GPL8304_CE_WBGene00000458_C | |||||||
GPL8673_C37E2_5P00046 | |||||||
GPL8673_C37E2_5P00429 | |||||||
GPL8673_C37E2_5P00761 | |||||||
GPL9450_C37E2.5 | |||||||
cea2.p.136522 | |||||||
Expression_cluster (177) | |||||||
Interaction (79) | |||||||
Map_info | Map | X | Position | 16.6652 | Error | 0.001448 | |
Positive | Positive_clone | C37E2 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Mapping_data | Multi_point | 4209 | |||||
4254 | |||||||
Pseudo_map_position | |||||||
Reference (34) | |||||||
Remark | [Burglin T] registered gene name | ||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||
Method | Gene |