WormBase Tree Display for Gene: WBGene00000249
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WBGene00000249 | SMap | S_parent | Sequence | T27F2 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name | CGC_name | bir-1 | Person_evidence | WBPerson250 | |||||
Sequence_name | T27F2.3 | ||||||||
Molecular_name | T27F2.3 | ||||||||
T27F2.3.1 | |||||||||
CE06521 | |||||||||
T27F2.3.2 | |||||||||
Other_name | CELE_T27F2.3 | Accession_evidence | NDB | BX284605 | |||||
Public_name | bir-1 | ||||||||
DB_info | Database | AceView | gene | 5M125 | |||||
WormQTL | gene | WBGene00000249 | |||||||
WormFlux | gene | WBGene00000249 | |||||||
NDB | locus_tag | CELE_T27F2.3 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00000249|UniProtKB=G5EFA2 | |||||||
family | PTHR46771 | ||||||||
NCBI | gene | 179597 | |||||||
RefSeq | protein | NM_073548.10 | |||||||
SwissProt | UniProtAcc | G5EFA2 | |||||||
TREEFAM | TREEFAM_ID | TF316930 | |||||||
UniProt_GCRP | UniProtAcc | G5EFA2 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | bir | ||||||||
Allele (22) | |||||||||
Strain | WBStrain00051386 | ||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (21) | |||||||||
Contained_in_operon | CEOP5296 | ||||||||
Ortholog (34) | |||||||||
Structured_description | Concise_description | bir-1 encodes a homolog of the baculoviral inhibitor-of-apoptosis (IAP) repeat (BIR) proteins (BIRPs) family; bir-1 is required for meiotic and mitotic chromosome segregation and for cytokinesis; BIR-1 localizes to meiotic and mitotic chromosomes and to the spindle midzone; BIR-1 forms a protein complex with CSC-1, ICP-1 and AIR-2. | Paper_evidence | WBPaper00004303 | |||||
WBPaper00004589 | |||||||||
WBPaper00005872 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
WBPerson567 | |||||||||
Date_last_updated | 04 Mar 2013 00:00:00 | ||||||||
Automated_description | Predicted to enable metal ion binding activity. Involved in several processes, including chromosome organization; egg-laying behavior; and inductive cell migration. Located in condensed chromosome and spindle midzone. Expressed in egg-laying apparatus; hypodermis; pharynx; rectal muscle; and somatic nervous system. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); ductal carcinoma in situ; and endometrial hyperplasia. Is an ortholog of human BIRC5 (baculoviral IAP repeat containing 5). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:0050866 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:593) | ||||
DOID:9256 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:593) | ||||||
DOID:11054 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:593) | ||||||
DOID:2671 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:593) | ||||||
DOID:0080365 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:593) | ||||||
DOID:4450 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:593) | ||||||
DOID:0060074 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:593) | ||||||
DOID:10283 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:593) | ||||||
DOID:6432 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:593) | ||||||
Molecular_info | Corresponding_CDS | T27F2.3 | |||||||
Corresponding_transcript | T27F2.3.1 | ||||||||
T27F2.3.2 | |||||||||
Other_sequence | CRC03813_1 | ||||||||
CR07657 | |||||||||
Associated_feature | WBsf647283 | ||||||||
WBsf977296 | |||||||||
WBsf977297 | |||||||||
WBsf1020480 | |||||||||
WBsf232532 | |||||||||
Experimental_info | RNAi_result (19) | ||||||||
Expr_pattern (11) | |||||||||
Drives_construct | WBCnstr00037630 | ||||||||
Construct_product | WBCnstr00037630 | ||||||||
Regulate_expr_cluster | WBPaper00045565:BIR-1_induced | ||||||||
WBPaper00045565:BIR-1_suppressed | |||||||||
Antibody | WBAntibody00000302 | ||||||||
WBAntibody00002920 | |||||||||
WBAntibody00002966 | |||||||||
Microarray_results | SMD_0T27F2.3 | ||||||||
SMD_T27F2.3 | |||||||||
193166_at | |||||||||
A_12_P111264 | |||||||||
Aff_T27F2.3 | |||||||||
GPL13394_WBGene00000249 | |||||||||
GPL13914_T27F2.3 | |||||||||
GPL14144_T27F2.3_166-225_0.940_3_A | |||||||||
GPL14144_T27F2.3_263-322_0.952_1_B | |||||||||
GPL14144_T27F2.3_41-100_0.728_57_C | |||||||||
GPL19516_CGZ0037304 | |||||||||
GPL19516_CGZ0037305 | |||||||||
GPL21109_T27F2.3.1 | |||||||||
GPL3518_CE06521 | |||||||||
GPL8304_CE_WBGene00000249_A | |||||||||
GPL8304_CE_WBGene00000249_B | |||||||||
GPL8673_T27F2_3P00121 | |||||||||
GPL8673_T27F2_3P00219 | |||||||||
GPL8673_T27F2_3P00291 | |||||||||
GPL9450_T27F2.3 | |||||||||
cea2.c.38843 | |||||||||
Expression_cluster (136) | |||||||||
Interaction (82) | |||||||||
Map_info (4) | |||||||||
Reference (32) | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |