WormBase Tree Display for Gene: WBGene00004027

WBGene00004027 SMap: S_parent: Sequence: Y49E10
  Identity: Version: 1
    Name: CGC_name: pie-1 Person_evidence: WBPerson498
      Sequence_name: Y49E10.14
      Molecular_name: Y49E10.14a
        Y49E10.14a.1
        CE28134
        Y49E10.14b
        CE45773
        Y49E10.14b.1
      Other_name: pic-1
        CELE_Y49E10.14 Accession_evidence: NDB BX284603
      Public_name: pie-1
    DB_info: Database: AceView gene 3N517
        WormQTL gene WBGene00004027
        WormFlux gene WBGene00004027
        NDB locus_tag CELE_Y49E10.14
        Panther gene CAEEL|WormBase=WBGene00004027|UniProtKB=Q94131
          family PTHR12547
        NCBI gene 176667
        RefSeq protein NM_001268238.3
            NM_001268237.2
        SwissProt UniProtAcc Q94131
        TREEFAM TREEFAM_ID TF318914
        UniProt_GCRP UniProtAcc Q94131
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:33 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: pie
    Allele (78)
    Legacy_information: [C.elegansII] zu154 : maternal effect lethal, often with two distinct pharynges; additional pharynx and intestinal tissue from P2 (transformed to EMS fate).OA1. Cloned: encodes zinc finger protein, localized to nuclei of germ line blastomeres. [Mello et al. 1992; Mango et al. 1994; EU; JJ]
    Strain (76)
    RNASeq_FPKM (74)
    GO_annotation (33)
    Ortholog (26)
    Paralog (20)
    Structured_description: Concise_description: pie-1 encodes a C-x8-C-x5-C-x3-H-type zinc-finger protein; maternally provided PIE-1 is essential for germline cell fate determination, as it functions as a repressor of RNA polymerase II-dependent gene expression in the developing germ line; PIE-1 localization, initially uniform and then concentrated in the posterior germ cell lineages, is regulated by other maternally supplied gene products including PAR-1, MEX-5, and MEX-6. Paper_evidence: WBPaper00004304
            WBPaper00004631
            WBPaper00005297
            WBPaper00005347
            WBPaper00005605
            WBPaper00005735
            WBPaper00005791
          Curator_confirmed: WBPerson1843
          Date_last_updated: 30 Nov 2004 00:00:00
      Automated_description: Predicted to enable mRNA 3'-UTR binding activity. Involved in several processes, including embryonic pattern specification; formation of primary germ layer; and negative regulation of nitrogen compound metabolic process. Located in several cellular components, including P granule; centrosome; and cytosol. Expressed in germ line; head muscle; and nerve ring. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: Y49E10.14a
      Y49E10.14b
    Corresponding_CDS_history: Y49E10.14:wp52
    Corresponding_transcript: Y49E10.14a.1
      Y49E10.14b.1
    Other_sequence: U62896
      CBC08706_1
      CRC03076_1
    Associated_feature: WBsf047506
      WBsf645660
      WBsf659608
      WBsf976032
      WBsf976033
      WBsf976034
      WBsf978688
      WBsf994644
      WBsf225904
    Transcription_factor: WBTranscriptionFactor000460
  Experimental_info: RNAi_result (65)
    Expr_pattern (17)
    Drives_construct (720)
    Construct_product (18)
    Regulate_expr_cluster: WBPaper00061478:pie-1(ne4303)_upregulated
      WBPaper00061478:pie-1(ne4433)_upregulated
    Antibody: WBAntibody00000118
      WBAntibody00000189
      WBAntibody00000697
      WBAntibody00001076
      WBAntibody00001395
      WBAntibody00001588
      WBAntibody00001589
    Microarray_results (24)
    Expression_cluster (152)
    Interaction (309)
    WBProcess: WBbiopr:00000017
  Map_info: Map: III Position: 17.7453 Error: 0.045821
    Well_ordered
    Positive: Inside_rearr: ctDf3
      Positive_clone: pJP604
        Y49E10 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point (11)
      Pos_neg_data: 8413
        8414
        8548
        8557
    Landmark_gene
  Reference: WBPaper00001473
    WBPaper00001584
    WBPaper00001635
    WBPaper00001670
    WBPaper00001785
    WBPaper00001797
    WBPaper00001901
    WBPaper00001947
    WBPaper00001957
    WBPaper00002000
    WBPaper00002012
    WBPaper00002156
    WBPaper00002190
    WBPaper00002239
    WBPaper00002330
    WBPaper00002479
    WBPaper00002491
    WBPaper00002526
    WBPaper00002527
    WBPaper00002564
    WBPaper00002572
    WBPaper00002573
    WBPaper00002654
    WBPaper00002661
    WBPaper00002734
    WBPaper00002774
    WBPaper00002801
    WBPaper00002870
    WBPaper00002871
    WBPaper00002877
    WBPaper00002923
    WBPaper00002939
    WBPaper00003030
    WBPaper00003061
    WBPaper00003068
    WBPaper00003129
    WBPaper00003170
    WBPaper00003175
    WBPaper00003198
    WBPaper00003325
    WBPaper00003331
    WBPaper00003363
    WBPaper00003382
    WBPaper00003391
    WBPaper00003990
    WBPaper00004112
    WBPaper00004115
    WBPaper00004134
    WBPaper00004151
    WBPaper00004230
    WBPaper00004304
    WBPaper00004323
    WBPaper00004333
    WBPaper00004400
    WBPaper00004449
    WBPaper00004455
    WBPaper00004519
    WBPaper00004545
    WBPaper00004549
    WBPaper00004550
    WBPaper00004634
    WBPaper00004890
    WBPaper00004995
    WBPaper00005046
    WBPaper00005095
    WBPaper00005198
    WBPaper00005295
    WBPaper00005297
    WBPaper00005498
    WBPaper00005575
    WBPaper00005605
    WBPaper00005637
    WBPaper00005791
    WBPaper00005930
    WBPaper00006004
    WBPaper00006085
    WBPaper00006157
    WBPaper00006192
    WBPaper00006199
    WBPaper00006203
    WBPaper00006223
    WBPaper00006235
    WBPaper00006311
    WBPaper00006320
    WBPaper00006404
    WBPaper00006475
    WBPaper00010177
    WBPaper00010203
    WBPaper00010271
    WBPaper00010463
    WBPaper00010467
    WBPaper00010533
    WBPaper00010538
    WBPaper00010539
    WBPaper00010540
    WBPaper00010668
    WBPaper00010692
    WBPaper00010737
    WBPaper00010744
    WBPaper00010770
    WBPaper00010792
    WBPaper00010882
    WBPaper00010885
    WBPaper00010886
    WBPaper00010932
    WBPaper00010990
    WBPaper00011055
    WBPaper00011120
    WBPaper00011137
    WBPaper00011155
    WBPaper00011225
    WBPaper00011252
    WBPaper00011469
    WBPaper00011730
    WBPaper00011999
    WBPaper00012433
    WBPaper00012574
    WBPaper00013493
    WBPaper00013500
    WBPaper00013507
    WBPaper00014684
    WBPaper00014868
    WBPaper00015102
    WBPaper00015178
    WBPaper00015432
    WBPaper00015604
    WBPaper00015681
    WBPaper00015787
    WBPaper00016897
    WBPaper00017081
    WBPaper00017188
    WBPaper00017189
    WBPaper00017291
    WBPaper00017294
    WBPaper00017385
    WBPaper00017386
    WBPaper00017726
    WBPaper00017741
    WBPaper00017774
    WBPaper00017832
    WBPaper00017838
    WBPaper00017962
    WBPaper00018018
    WBPaper00018179
    WBPaper00018388
    WBPaper00018390
    WBPaper00018611
    WBPaper00018617
    WBPaper00018647
    WBPaper00018648
    WBPaper00018714
    WBPaper00018746
    WBPaper00018888
    WBPaper00019039
    WBPaper00019741
    WBPaper00019752
    WBPaper00019756
    WBPaper00019759
    WBPaper00019765
    WBPaper00021658
    WBPaper00021715
    WBPaper00021736
    WBPaper00021768
    WBPaper00021850
    WBPaper00021862
    WBPaper00021917
    WBPaper00022019
    WBPaper00022254
    WBPaper00022324
    WBPaper00022350
    WBPaper00022386
    WBPaper00022549
    WBPaper00022551
    WBPaper00022557
    WBPaper00022606
    WBPaper00022686
    WBPaper00022687
    WBPaper00022700
    WBPaper00022745
    WBPaper00022754
    WBPaper00022790
    WBPaper00022856
    WBPaper00022879
    WBPaper00022941
    WBPaper00023210
    WBPaper00023229
    WBPaper00023329
    WBPaper00023397
    WBPaper00023476
    WBPaper00023619
    WBPaper00023644
    WBPaper00023683
    WBPaper00023694
    WBPaper00023705
    WBPaper00023708
    WBPaper00023773
    WBPaper00024449
    WBPaper00024507
    WBPaper00024619
    WBPaper00025032
    WBPaper00025816
    WBPaper00025835
    WBPaper00025949
    WBPaper00025950
    WBPaper00026622
    WBPaper00026630
    WBPaper00026975
    WBPaper00027038
    WBPaper00027080
    WBPaper00027224
    WBPaper00027230
    WBPaper00027251
    WBPaper00027259
    WBPaper00027260
    WBPaper00027268
    WBPaper00027298
    WBPaper00027309
    WBPaper00027310
    WBPaper00027315
    WBPaper00027320
    WBPaper00027745
    WBPaper00027796
    WBPaper00027949
    WBPaper00027952
    WBPaper00027982
    WBPaper00028560
    WBPaper00028568
    WBPaper00028588
    WBPaper00028736
    WBPaper00029038
    WBPaper00030269
    WBPaper00030472
    WBPaper00031434
    WBPaper00031439
    WBPaper00031555
    WBPaper00032220
    WBPaper00032265
    WBPaper00032287
    WBPaper00032302
    WBPaper00032497
    WBPaper00032951
    WBPaper00033355
    WBPaper00033449
    WBPaper00034376
    WBPaper00034459
    WBPaper00034727
    WBPaper00034805
    WBPaper00035297
    WBPaper00036486
    WBPaper00036822
    WBPaper00036909
    WBPaper00037129
    WBPaper00037443
    WBPaper00037685
    WBPaper00038409
    WBPaper00038676
    WBPaper00038707
    WBPaper00038718
    WBPaper00039209
    WBPaper00039463
    WBPaper00039471
    WBPaper00039627
    WBPaper00040688
    WBPaper00041891
    WBPaper00042808
    WBPaper00042959
    WBPaper00044000
    WBPaper00046196
    WBPaper00047039
    WBPaper00047206
    WBPaper00047234
    WBPaper00047333
    WBPaper00047842
    WBPaper00048124
    WBPaper00048493
    WBPaper00050959
    WBPaper00053488
    WBPaper00053609
    WBPaper00054584
    WBPaper00054941
    WBPaper00055361
    WBPaper00055649
    WBPaper00056635
    WBPaper00056676
    WBPaper00056904
    WBPaper00057093
    WBPaper00057125
    WBPaper00057627
    WBPaper00057808
    WBPaper00057891
    WBPaper00058083
    WBPaper00059440
    WBPaper00060886
    WBPaper00061137
    WBPaper00061478
    WBPaper00061495
    WBPaper00062120
    WBPaper00062371
    WBPaper00062457
    WBPaper00062587
    WBPaper00063073
    WBPaper00063228
    WBPaper00063553
    WBPaper00063960
    WBPaper00064298
    WBPaper00064594
    WBPaper00064680
    WBPaper00064947
    WBPaper00064980
    WBPaper00065093
    WBPaper00065275
    WBPaper00065789
    WBPaper00065940
    WBPaper00065997
  Method: Gene