WormBase Tree Display for Gene: WBGene00012354

WBGene00012354 SMap: S_parent: Sequence: W09C5
  Identity: Version: 2
    Name: CGC_name: cox-4 Person_evidence: WBPerson117
            WBPerson7169
      Sequence_name: W09C5.8
      Molecular_name: W09C5.8
        W09C5.8.1
        CE20171
      Other_name: CELE_W09C5.8 Accession_evidence: NDB BX284601
      Public_name: cox-4
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:53 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 05 Sep 2017 13:25:30 WBPerson2970 Name_change: CGC_name: cox-4
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: cox
    Allele (24)
    Strain: WBStrain00037231
      WBStrain00022511
      WBStrain00047268
    RNASeq_FPKM (74)
    GO_annotation (10)
    Ortholog (44)
    Structured_description: Concise_description: W09C5.8 encodes the C. elegans ortholog of the cytochrome c oxidase (COX) subunit IV (COX IV); loss of W09C5.8 activity via RNAi results in a shortened life span, reduced fertility, and defects in mitochondrial respiratory chain function. Paper_evidence: WBPaper00032427
          Curator_confirmed: WBPerson1843
          Date_last_updated: 08 Nov 2010 00:00:00
      Automated_description: Involved in mitochondrial electron transport, cytochrome c to oxygen. Predicted to be located in mitochondrial inner membrane. Predicted to be part of mitochondrial respiratory chain complex IV. Human ortholog(s) of this gene implicated in cytochrome-c oxidase deficiency disease. Is an ortholog of human COX4I1 (cytochrome c oxidase subunit 4I1) and COX4I2 (cytochrome c oxidase subunit 4I2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0070501 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2265)
  Molecular_info: Corresponding_CDS: W09C5.8
    Corresponding_transcript: W09C5.8.1
    Other_sequence (131)
    Associated_feature: WBsf649714
      WBsf655327
      WBsf220533
      WBsf220534
      WBsf220535
  Experimental_info: RNAi_result (21)
    Expr_pattern: Expr1028081
      Expr1035471
      Expr1158573
      Expr2006884
      Expr2025111
    Drives_construct: WBCnstr00029984
    Construct_product: WBCnstr00029984
    Microarray_results (23)
    Expression_cluster (110)
    Interaction: WBInteraction000032338
      WBInteraction000045761
      WBInteraction000109820
      WBInteraction000111432
      WBInteraction000111663
      WBInteraction000111683
      WBInteraction000123182
      WBInteraction000126869
      WBInteraction000126870
      WBInteraction000127220
      WBInteraction000135201
      WBInteraction000138135
      WBInteraction000139280
      WBInteraction000153351
      WBInteraction000153381
      WBInteraction000153406
      WBInteraction000153436
      WBInteraction000153472
      WBInteraction000153613
      WBInteraction000154083
      WBInteraction000155599
      WBInteraction000155662
      WBInteraction000155694
      WBInteraction000155734
      WBInteraction000155754
      WBInteraction000155755
      WBInteraction000155756
      WBInteraction000156369
      WBInteraction000156432
      WBInteraction000168001
      WBInteraction000196664
      WBInteraction000202896
      WBInteraction000213361
      WBInteraction000227409
      WBInteraction000248584
      WBInteraction000251803
      WBInteraction000252262
      WBInteraction000265961
      WBInteraction000268050
      WBInteraction000268803
      WBInteraction000279699
      WBInteraction000283593
      WBInteraction000290529
      WBInteraction000324079
      WBInteraction000342723
      WBInteraction000362458
      WBInteraction000368930
      WBInteraction000369003
      WBInteraction000376623
      WBInteraction000377859
      WBInteraction000392075
      WBInteraction000393348
      WBInteraction000415310
      WBInteraction000422855
      WBInteraction000431508
      WBInteraction000435366
      WBInteraction000438977
      WBInteraction000443521
      WBInteraction000447566
      WBInteraction000448681
      WBInteraction000452073
      WBInteraction000455859
      WBInteraction000536349
      WBInteraction000536354
      WBInteraction000536359
      WBInteraction000552879
      WBInteraction000553899
      WBInteraction000558488
      WBInteraction000559543
      WBInteraction000561983
      WBInteraction000572179
      WBInteraction000572488
      WBInteraction000573743
      WBInteraction000579825
      WBInteraction000583308
      WBInteraction000586348
  Map_info: Map: I Position: 21.6359
    Positive: Positive_clone: W09C5 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (15)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene