enol-1 is orthologous to human ENOLASE 1 (also CRYSTALLIN, TAU; ENO1; OMIM:172430), which when mutated leads to spherocytic red cell enolase deficiency.
Predicted to enable phosphopyruvate hydratase activity. Predicted to be involved in glycolytic process. Predicted to be located in cytoplasm. Predicted to be part of phosphopyruvate hydratase complex. Expressed in head. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; migraine without aura; neuroendocrine carcinoma; and prostate cancer. Is an ortholog of human ENO2 (enolase 2).
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.