WormBase Tree Display for Gene: WBGene00010317

WBGene00010317 SMap: S_parent: Sequence: F59B8
  Identity: Version: 2
    Name: CGC_name: idh-1 Person_evidence: WBPerson261
      Sequence_name: F59B8.2
      Molecular_name: F59B8.2a
        F59B8.2a.1
        CE03436
        F59B8.2b
        CE47303
        F59B8.2c
        CE47163
        F59B8.2b.1
        F59B8.2c.1
      Other_name: CELE_F59B8.2 Accession_evidence: NDB BX284604
      Public_name: idh-1
    DB_info: Database (12)
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:51 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 08 Oct 2008 10:23:18 WBPerson2970 Name_change: CGC_name: idh-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: idh
    Allele (27)
    Strain: WBStrain00003527
      WBStrain00002807
      WBStrain00032810
    RNASeq_FPKM (74)
    GO_annotation (16)
    Ortholog (38)
    Paralog: WBGene00007942 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: idh-1 encodes a predicted cytosolic isocitrate dehydrogenase; by homology, IDH-1 is predicted to catalyze the formation of alpha-ketoglutarate from isocitrate. Curator_confirmed: WBPerson1843
          Date_last_updated: 26 Oct 2011 00:00:00
      Automated_description: Predicted to enable isocitrate dehydrogenase (NADP+) activity. Predicted to be involved in NADP metabolic process and isocitrate metabolic process. Predicted to be located in cytosol; mitochondrion; and peroxisome. Expressed in tail. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); glioblastoma; and hematologic cancer (multiple). Is an ortholog of human IDH1 (isocitrate dehydrogenase (NADP(+)) 1). Paper_evidence: WBPaper00065943
          Curator_confirmed (2)
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:5016 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:5382)
      DOID:4928 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:5382)
      DOID:3068 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:5382)
      DOID:0050908 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:5382)
      DOID:3910 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:5382)
      DOID:3070 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:5382)
      DOID:3907 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:5382)
      DOID:417 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:5382)
      DOID:9119 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:5382)
  Molecular_info: Corresponding_CDS: F59B8.2a
      F59B8.2b
      F59B8.2c
    Corresponding_transcript: F59B8.2a.1
      F59B8.2b.1
      F59B8.2c.1
    Other_sequence (57)
    Associated_feature: WBsf668157
      WBsf668158
      WBsf981804
      WBsf997420
      WBsf1017963
      WBsf230567
      WBsf230568
      WBsf230569
  Experimental_info: RNAi_result: WBRNAi00090634 Inferred_automatically: RNAi_primary
      WBRNAi00080812 Inferred_automatically: RNAi_primary
      WBRNAi00065271 Inferred_automatically: RNAi_primary
      WBRNAi00016084 Inferred_automatically: RNAi_primary
      WBRNAi00001636 Inferred_automatically: RNAi_primary
      WBRNAi00033293 Inferred_automatically: RNAi_primary
      WBRNAi00049155 Inferred_automatically: RNAi_primary
      WBRNAi00113980 Inferred_automatically: RNAi_primary
    Expr_pattern: Chronogram1063
      Chronogram1718
      Expr6263
      Expr6264
      Expr1018358
      Expr1034502
      Expr1152898
      Expr2012669
      Expr2030905
    Drives_construct: WBCnstr00003334
      WBCnstr00004581
      WBCnstr00031510
    Construct_product: WBCnstr00031510
    Microarray_results (25)
    Expression_cluster (219)
    Interaction: WBInteraction000119233
      WBInteraction000120721
      WBInteraction000122004
      WBInteraction000123831
      WBInteraction000133640
      WBInteraction000138797
      WBInteraction000140707
      WBInteraction000143205
      WBInteraction000149005
      WBInteraction000163566
      WBInteraction000164196
      WBInteraction000179206
      WBInteraction000181367
      WBInteraction000184338
      WBInteraction000188558
      WBInteraction000190119
      WBInteraction000192426
      WBInteraction000192737
      WBInteraction000202882
      WBInteraction000211766
      WBInteraction000213412
      WBInteraction000214036
      WBInteraction000218625
      WBInteraction000219860
      WBInteraction000224622
      WBInteraction000226310
      WBInteraction000229115
      WBInteraction000232648
      WBInteraction000232799
      WBInteraction000235240
      WBInteraction000235408
      WBInteraction000245152
      WBInteraction000251329
      WBInteraction000252696
      WBInteraction000257948
      WBInteraction000260743
      WBInteraction000269945
      WBInteraction000270329
      WBInteraction000270890
      WBInteraction000274921
      WBInteraction000279127
      WBInteraction000279875
      WBInteraction000280935
      WBInteraction000285770
      WBInteraction000298105
      WBInteraction000298106
      WBInteraction000298107
      WBInteraction000302368
      WBInteraction000314208
      WBInteraction000318442
      WBInteraction000333841
      WBInteraction000337127
      WBInteraction000338483
      WBInteraction000338839
      WBInteraction000354089
      WBInteraction000354196
      WBInteraction000354602
      WBInteraction000356831
      WBInteraction000357765
      WBInteraction000359857
      WBInteraction000363958
      WBInteraction000364881
      WBInteraction000364882
      WBInteraction000364884
      WBInteraction000366425
      WBInteraction000369635
      WBInteraction000370890
      WBInteraction000373084
      WBInteraction000373602
      WBInteraction000375594
      WBInteraction000376357
      WBInteraction000377265
      WBInteraction000383803
      WBInteraction000385594
      WBInteraction000401231
      WBInteraction000413341
      WBInteraction000430230
      WBInteraction000451919
      WBInteraction000465894
      WBInteraction000471226
      WBInteraction000534787
      WBInteraction000534788
      WBInteraction000542765
      WBInteraction000549547
      WBInteraction000553199
      WBInteraction000554303
      WBInteraction000554415
      WBInteraction000554686
      WBInteraction000562251
      WBInteraction000563952
      WBInteraction000565027
      WBInteraction000565086
      WBInteraction000565115
      WBInteraction000568802
      WBInteraction000568855
      WBInteraction000570436
      WBInteraction000572261
      WBInteraction000572684
      WBInteraction000572924
      WBInteraction000574162
      WBInteraction000577907
      WBInteraction000580695
      WBInteraction000582810
  Map_info: Map: IV Position: 4.24582 Error: 0.002337
    Positive: Positive_clone: F59B8 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (11)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene