WormBase Tree Display for Gene: WBGene00009448

WBGene00009448 SMap: S_parent: Sequence: F35H8
  Identity: Version: 2
    Name: CGC_name: zfp-2 Person_evidence: WBPerson2214
            WBPerson585
      Sequence_name: F35H8.3
      Molecular_name: F35H8.3
        F35H8.3.1
        CE00981
      Other_name: CELE_F35H8.3 Accession_evidence: NDB BX284602
      Public_name: zfp-2
    DB_info: Database: AceView gene 2J849
        WormQTL gene WBGene00009448
        WormFlux gene WBGene00009448
        NDB locus_tag CELE_F35H8.3
        Panther gene CAEEL|WormBase=WBGene00009448|UniProtKB=Q20082
          family PTHR24393
        NCBI gene 174505
        RefSeq protein NM_063654.6
        SwissProt UniProtAcc Q20082
        TREEFAM TREEFAM_ID TF350994
        UniProt_GCRP UniProtAcc Q20082
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:50 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 02 Mar 2006 11:42:04 WBPerson2970 Name_change: CGC_name: zfp-2
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: zfp
    Allele (34)
    RNASeq_FPKM (74)
    GO_annotation: 00067085
      00067086
      00067087
      00067088
      00067089
      00067090
      00067091
      00067092
      00067093
    Ortholog (32)
    Paralog (16)
    Structured_description: Concise_description: zfp-2 encodes a zinc-finger transcription factor; loss of zfp-2 and lin-35/Rb results in almost complete sterility accompanied by defects in somatic gonad development and vulval morphology, as well as polyploidization of somatic cell nuclei; loss of zfp-2 activity by itself reveals that zfp-2 is also required for cosuppression, inhibition of RNAi of some genes, and wild-type levels of expression of a rol-6 extrachromosomal array; a zfp-2::GFP promoter fusion construct is expressed in vulval cells and all somatic gonad structures, such as the spermatheca, sheath cells, uterine cells and distal tip cells (DTCs). Paper_evidence: WBPaper00025139
            WBPaper00029258
          Curator_confirmed: WBPerson1843
          Date_last_updated: 14 Jan 2008 00:00:00
      Automated_description: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in body wall musculature; hermaphrodite gonad; pharynx; seam cell; and vulva. Is an ortholog of human ZBTB32 (zinc finger and BTB domain containing 32). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F35H8.3
    Corresponding_transcript: F35H8.3.1
    Other_sequence (23)
    Associated_feature: WBsf644574
      WBsf978441
      WBsf989074
      WBsf221897
      WBsf221898
      WBsf221899
    Transcription_factor: WBTranscriptionFactor000230
  Experimental_info: RNAi_result (13)
    Expr_pattern: Expr4593
      Expr7541
      Expr1016356
      Expr1034134
      Expr1150301
      Expr2018129
      Expr2036266
    Drives_construct: WBCnstr00012102
      WBCnstr00012686
      WBCnstr00032175
    Construct_product: WBCnstr00017962
      WBCnstr00021768
      WBCnstr00032175
    Microarray_results (19)
    Expression_cluster (134)
    Interaction: WBInteraction000008263
      WBInteraction000113424
      WBInteraction000181506
      WBInteraction000181703
      WBInteraction000195282
      WBInteraction000208583
      WBInteraction000209769
      WBInteraction000209922
      WBInteraction000213917
      WBInteraction000213987
      WBInteraction000214767
      WBInteraction000215961
      WBInteraction000226087
      WBInteraction000226464
      WBInteraction000226961
      WBInteraction000228758
      WBInteraction000232468
      WBInteraction000233613
      WBInteraction000243348
      WBInteraction000244512
      WBInteraction000246609
      WBInteraction000252490
      WBInteraction000252753
      WBInteraction000259845
      WBInteraction000262750
      WBInteraction000269566
      WBInteraction000275098
      WBInteraction000279580
      WBInteraction000282155
      WBInteraction000282314
      WBInteraction000283950
      WBInteraction000287238
      WBInteraction000295178
      WBInteraction000296990
      WBInteraction000297033
      WBInteraction000301038
      WBInteraction000301381
      WBInteraction000302105
      WBInteraction000303316
      WBInteraction000306511
      WBInteraction000309677
      WBInteraction000311956
      WBInteraction000312459
      WBInteraction000313190
      WBInteraction000313220
      WBInteraction000317473
      WBInteraction000320712
      WBInteraction000334977
      WBInteraction000335184
      WBInteraction000341862
      WBInteraction000342081
      WBInteraction000342955
      WBInteraction000347668
      WBInteraction000352814
      WBInteraction000355644
      WBInteraction000355719
      WBInteraction000357973
      WBInteraction000358082
      WBInteraction000360583
      WBInteraction000362197
      WBInteraction000362244
      WBInteraction000363321
      WBInteraction000365327
      WBInteraction000365464
      WBInteraction000373442
      WBInteraction000380969
      WBInteraction000389056
      WBInteraction000389972
      WBInteraction000392509
      WBInteraction000393740
      WBInteraction000394430
      WBInteraction000395979
      WBInteraction000401680
      WBInteraction000401911
      WBInteraction000405923
      WBInteraction000408481
      WBInteraction000411456
      WBInteraction000413210
      WBInteraction000416694
      WBInteraction000419325
      WBInteraction000421381
      WBInteraction000428066
      WBInteraction000429235
      WBInteraction000431786
      WBInteraction000434076
      WBInteraction000434346
      WBInteraction000435267
      WBInteraction000437466
      WBInteraction000440344
      WBInteraction000441088
      WBInteraction000443524
      WBInteraction000444289
      WBInteraction000444671
      WBInteraction000444851
      WBInteraction000449631
      WBInteraction000449727
      WBInteraction000450850
      WBInteraction000457225
      WBInteraction000458260
      WBInteraction000459550
      WBInteraction000459615
      WBInteraction000461674
      WBInteraction000533538
      WBInteraction000582404
  Map_info: Map: II Position: 1.58987 Error: 0.007886
    Positive: Positive_clone: F35H8 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (3)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene