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WormBase Tree Display for Gene: WBGene00008458

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Name Class

WBGene00008458SMapS_parentSequenceE02H1
Identity (6)
Gene_infoBiotypeSO:0001217
Allele (18)
StrainWBStrain00037116
RNASeq_FPKM (74)
GO_annotation (21)
Contained_in_operonCEOP2436
Ortholog (36)
ParalogWBGene00006391Caenorhabditis elegansFrom_analysisPanther
Structured_descriptionConcise_descriptionE02H1.6 encodes an ortholog of human TAF9 (OMIM:600822; also known asAK6, adrenal gland protein AD-004 like protein, ADLP) and of S.cerevisiae Fap7p; like its human ortholog, E02H1.6 is nuclear, and ispredicted to likewise be a TATA box binding protein (TBP)-associatedfactor mediating activation of RNA polymerase II; E02H1.6 prefers ATPand dATP as phosphate donors; E02H1.6's biochemical activity is unusual,since it also prefers AMP and dAMP as substrates, and tolerates CMP, TMPand shikimate acid as substrates as well; since yeast Fap7p promotespre-rRNA cleavage, E02H1.6 may be multifunctional; in RNAi assays,E02H1.6 is required for normally fast growth; E02H1.6 is coexpressedwith pme-2 in an operon, and thus, like PME-2, may function in DNArepair.Paper_evidenceWBPaper00005600
WBPaper00027687
WBPaper00028896
WBPaper00028897
WBPaper00028898
WBPaper00028899
Curator_confirmedWBPerson567
Date_last_updated20 Feb 2007 00:00:00
Automated_descriptionPredicted to enable ATP binding activity and adenylate kinase activity. Predicted to be involved in nucleoside monophosphate phosphorylation and phosphorylation. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human AK6 (adenylate kinase 6).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSE02H1.6
Corresponding_CDS_historyE02H1.6:wp54
Corresponding_transcriptE02H1.6.1
Other_sequence (35)
Associated_featureWBsf221907
Experimental_infoRNAi_resultWBRNAi00007974Inferred_automaticallyRNAi_primary
WBRNAi00012646Inferred_automaticallyRNAi_primary
WBRNAi00065873Inferred_automaticallyRNAi_primary
WBRNAi00043602Inferred_automaticallyRNAi_primary
WBRNAi00030468Inferred_automaticallyRNAi_primary
Expr_patternExpr4325
Expr1020050
Expr1033684
Expr1147592
Expr2002134
Expr2020357
Drives_constructWBCnstr00011923
WBCnstr00032949
Construct_productWBCnstr00011923
WBCnstr00032949
AntibodyWBAntibody00001104
Microarray_results (19)
Expression_cluster (99)
InteractionWBInteraction000037738
WBInteraction000039122
WBInteraction000040004
WBInteraction000040360
WBInteraction000041467
WBInteraction000042228
WBInteraction000106942
WBInteraction000106998
WBInteraction000107192
WBInteraction000107193
WBInteraction000107194
WBInteraction000107195
WBInteraction000107196
WBInteraction000108947
WBInteraction000109011
WBInteraction000109012
WBInteraction000109013
WBInteraction000109014
WBInteraction000118096
WBInteraction000125668
WBInteraction000130759
WBInteraction000130908
WBInteraction000131083
WBInteraction000131084
WBInteraction000131085
WBInteraction000131086
WBInteraction000131087
WBInteraction000131088
WBInteraction000131089
WBInteraction000131090
WBInteraction000131091
WBInteraction000131092
WBInteraction000131093
WBInteraction000131094
WBInteraction000131095
WBInteraction000131096
WBInteraction000131097
WBInteraction000131098
WBInteraction000131099
WBInteraction000131100
WBInteraction000131101
WBInteraction000131102
WBInteraction000131103
WBInteraction000131104
WBInteraction000131881
WBInteraction000131991
WBInteraction000148536
WBInteraction000157372
WBInteraction000167721
WBInteraction000169818
WBInteraction000174182
WBInteraction000174371
WBInteraction000174708
WBInteraction000185390
WBInteraction000193534
WBInteraction000201440
WBInteraction000204116
WBInteraction000210067
WBInteraction000211917
WBInteraction000213377
WBInteraction000220801
WBInteraction000227194
WBInteraction000231504
WBInteraction000233966
WBInteraction000236171
WBInteraction000242718
WBInteraction000262530
WBInteraction000266665
WBInteraction000267418
WBInteraction000276357
WBInteraction000280180
WBInteraction000283987
WBInteraction000292570
WBInteraction000293796
WBInteraction000299476
WBInteraction000302023
WBInteraction000310498
WBInteraction000341003
WBInteraction000341004
WBInteraction000342616
WBInteraction000343473
WBInteraction000348153
WBInteraction000352662
WBInteraction000355746
WBInteraction000371749
WBInteraction000379405
WBInteraction000380321
WBInteraction000392703
WBInteraction000405890
WBInteraction000410896
WBInteraction000415431
WBInteraction000427941
WBInteraction000432682
WBInteraction000436655
WBInteraction000449617
WBInteraction000452377
WBInteraction000453063
WBInteraction000466996
WBInteraction000468204
WBInteraction000469842
WBInteraction000575073
Map_infoPositivePositive_cloneE02H1Inferred_automaticallyFrom sequence, transcript, pseudogene data
Interpolated_map_positionII1.61605
ReferenceWBPaper00027687
WBPaper00038491
WBPaper00041771
WBPaper00055090
WBPaper00065308
MethodGene