WormBase Tree Display for Gene: WBGene00004755
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| WBGene00004755 | SMap | S_parent | Sequence | F12F6 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | sec-24.1 | Person_evidence | WBPerson297 | |||||
| Sequence_name | F12F6.6 | ||||||||
| Molecular_name | F12F6.6 | ||||||||
| F12F6.6.1 | |||||||||
| CE05594 | |||||||||
| Other_name | CELE_F12F6.6 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | sec-24.1 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:36 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | sec | ||||||||
| Allele (47) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (14) | |||||||||
| Contained_in_operon | CEOP4452 | ||||||||
| Ortholog (60) | |||||||||
| Paralog | WBGene00004756 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | sec-24.1 encodes one of two C. elegans Sec24 homologs; in Saccharomyces cerevisiae, Sec24 is a member of the Sec24-Sec23 subunit of the COPII coat complex, assembly of which is essential for the first step of secretory protein transport from the endoplasmic reticulum (ER) to the Golgi; by homology with Sec24, SEC-24.1 is predicted to facilitate vesicle cargo selection, and likely contains multiple, independent sites for binding to secreted proteins; loss of sec-24.1 activity via RNAi indicates that SEC-24.1 is required for cuticle secretion and oogenesis. | Paper_evidence | WBPaper00011684 | |||||
| WBPaper00013299 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable SNARE binding activity and zinc ion binding activity. Predicted to be involved in COPII-coated vesicle cargo loading. Predicted to be located in endoplasmic reticulum exit site. Predicted to be part of COPII vesicle coat. Expressed widely. Human ortholog(s) of this gene implicated in Cole-Carpenter syndrome. Is an ortholog of human SEC24D (SEC24 homolog D, COPII coat complex component). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0060438 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10706) | ||||
| Molecular_info | Corresponding_CDS | F12F6.6 | |||||||
| Corresponding_transcript | F12F6.6.1 | ||||||||
| Other_sequence (65) | |||||||||
| Associated_feature | WBsf668347 | ||||||||
| WBsf981824 | |||||||||
| WBsf997872 | |||||||||
| WBsf997873 | |||||||||
| WBsf997874 | |||||||||
| WBsf1018224 | |||||||||
| WBsf230894 | |||||||||
| WBsf230895 | |||||||||
| Experimental_info | RNAi_result (12) | ||||||||
| Expr_pattern | Expr5746 | ||||||||
| Expr13312 | |||||||||
| Expr1017366 | |||||||||
| Expr1032352 | |||||||||
| Expr1148399 | |||||||||
| Expr2015714 | |||||||||
| Expr2033946 | |||||||||
| Drives_construct | WBCnstr00002791 | ||||||||
| WBCnstr00035408 | |||||||||
| Construct_product | WBCnstr00018415 | ||||||||
| WBCnstr00018416 | |||||||||
| WBCnstr00035408 | |||||||||
| Microarray_results (23) | |||||||||
| Expression_cluster (136) | |||||||||
| Interaction | WBInteraction000035785 | ||||||||
| WBInteraction000043955 | |||||||||
| WBInteraction000047101 | |||||||||
| WBInteraction000049977 | |||||||||
| WBInteraction000114955 | |||||||||
| WBInteraction000133130 | |||||||||
| WBInteraction000178741 | |||||||||
| WBInteraction000198861 | |||||||||
| WBInteraction000231672 | |||||||||
| WBInteraction000240518 | |||||||||
| WBInteraction000262290 | |||||||||
| WBInteraction000275785 | |||||||||
| WBInteraction000289944 | |||||||||
| WBInteraction000300929 | |||||||||
| WBInteraction000302043 | |||||||||
| WBInteraction000325430 | |||||||||
| WBInteraction000328090 | |||||||||
| WBInteraction000337423 | |||||||||
| WBInteraction000360135 | |||||||||
| WBInteraction000362135 | |||||||||
| WBInteraction000364898 | |||||||||
| WBInteraction000368680 | |||||||||
| WBInteraction000374352 | |||||||||
| WBInteraction000378101 | |||||||||
| WBInteraction000385710 | |||||||||
| WBInteraction000392370 | |||||||||
| WBInteraction000392637 | |||||||||
| WBInteraction000409621 | |||||||||
| WBInteraction000418344 | |||||||||
| WBInteraction000425248 | |||||||||
| WBInteraction000434806 | |||||||||
| WBInteraction000437395 | |||||||||
| WBInteraction000438106 | |||||||||
| WBInteraction000460281 | |||||||||
| WBInteraction000520631 | |||||||||
| WBInteraction000522917 | |||||||||
| WBInteraction000523294 | |||||||||
| WBInteraction000523295 | |||||||||
| WBInteraction000543849 | |||||||||
| WBInteraction000549230 | |||||||||
| WBInteraction000550149 | |||||||||
| WBInteraction000559194 | |||||||||
| WBInteraction000563217 | |||||||||
| WBInteraction000564267 | |||||||||
| WBInteraction000564948 | |||||||||
| WBInteraction000568820 | |||||||||
| WBInteraction000572389 | |||||||||
| WBInteraction000577311 | |||||||||
| WBInteraction000577772 | |||||||||
| WBInteraction000583115 | |||||||||
| WBInteraction000584901 | |||||||||
| WBInteraction000586695 | |||||||||
| Map_info | Map | IV | Position | 5.00291 | Error | 0.000895 | |||
| Positive | Positive_clone | F12F6 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00028945 | ||||||||
| WBPaper00038491 | |||||||||
| WBPaper00049330 | |||||||||
| WBPaper00050029 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00058870 | |||||||||
| WBPaper00060970 | |||||||||
| WBPaper00062332 | |||||||||
| WBPaper00064057 | |||||||||
| Remark | Sequence connection from [Johnstone IL], [020809 krb] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
