WormBase Tree Display for Gene: WBGene00003890
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WBGene00003890 | SMap | S_parent | Sequence | T20H4 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | osm | ||||||
Allele (30) | |||||||
Legacy_information | [C.elegansII] n1602 : specifically defective in osmotic avoidance; normal chemotaxis; normal garlic avoidance; normal nose touch response. NA1. Cloned: cosmid rescue [Bargmann et al. 1990; CX, KP] | ||||||
Strain | WBStrain00008277 | ||||||
WBStrain00008292 | |||||||
WBStrain00008293 | |||||||
WBStrain00008294 | |||||||
WBStrain00029473 | |||||||
WBStrain00027082 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (12) | |||||||
Ortholog (22) | |||||||
Structured_description | Concise_description | osm-10 encodes a novel protein conserved amongst several Caenorhabditis species; osm-10 activity is required for normal osmosensory signaling in the ASH sensory neuron; in regulating ASH-mediated osmosensation, osm-10 interacts genetically with eos-1 and eos-2; OSM-10 is expressed in the ASH, ASI, PHA, and PHB sensory neurons beginning just prior to hatching and continuing through larval and adult stages; OSM-10 localizes to cell bodies, sensory processes, and axons. | Paper_evidence | WBPaper00003408 | |||
Curator_confirmed | WBPerson1843 | ||||||
Date_last_updated | 25 Sep 2006 00:00:00 | ||||||
Automated_description | Enables osmosensor activity. Involved in osmosensory signaling pathway. Located in axon; cytoplasm; and neuronal cell body. | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Disease_relevance | Mutations in the human NADH-Ubiquinone oxidoreductase Fe-S protein 8 (NDUFS8; orthologous to elegans T20H4.1), are associated with Leigh syndrome, which is an an early-onset progressive neurodegenerative disorder, characterized by progressive loss of mental and movement abilities (psychomotor regression) and typically results in death within a couple of years, usually due to respiratory failure. | Homo sapiens | Accession_evidence | OMIM | 256000 | |
602141 | |||||||
Curator_confirmed | WBPerson324 | ||||||
Date_last_updated | 15 Jun 2012 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | T20H4.1a | |||||
T20H4.1b | |||||||
Corresponding_transcript | T20H4.1a.1 | ||||||
T20H4.1b.1 | |||||||
Associated_feature | WBsf645329 | ||||||
WBsf225227 | |||||||
WBsf225228 | |||||||
WBsf225229 | |||||||
Experimental_info | RNAi_result | WBRNAi00035727 | Inferred_automatically | RNAi_primary | |||
WBRNAi00053670 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00018934 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00005588 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00065896 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Chronogram614 | ||||||
Expr515 | |||||||
Expr1266 | |||||||
Expr6725 | |||||||
Expr15400 | |||||||
Expr1022236 | |||||||
Expr1031833 | |||||||
Expr1157225 | |||||||
Expr2014639 | |||||||
Expr2032872 | |||||||
Drives_construct (17) | |||||||
Construct_product | WBCnstr00012411 | ||||||
WBCnstr00022367 | |||||||
WBCnstr00035810 | |||||||
Antibody | WBAntibody00000213 | ||||||
Microarray_results (19) | |||||||
Expression_cluster (104) | |||||||
Interaction | WBInteraction000000797 | ||||||
WBInteraction000000798 | |||||||
WBInteraction000126393 | |||||||
WBInteraction000147211 | |||||||
WBInteraction000161324 | |||||||
WBInteraction000180432 | |||||||
WBInteraction000188286 | |||||||
WBInteraction000256324 | |||||||
WBInteraction000304021 | |||||||
WBInteraction000352848 | |||||||
WBInteraction000412807 | |||||||
WBInteraction000466208 | |||||||
WBInteraction000569148 | |||||||
WBInteraction000569149 | |||||||
Map_info | Map | III | Position | -0.764685 | Error | 0.000739 | |
Well_ordered | |||||||
Positive | Positive_clone | T20H4 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Mapping_data | 2_point | 3719 | |||||
Multi_point | 1363 | ||||||
4042 | |||||||
4043 | |||||||
4146 | |||||||
Pos_neg_data | 3720 | ||||||
3721 | |||||||
Reference (39) | |||||||
Method | Gene |