WormBase Tree Display for Gene: WBGene00003474
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| WBGene00003474 | SMap | S_parent | Sequence | T08G5 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | mtl-2 | Person_evidence | WBPerson1414 | |||||
| Sequence_name | T08G5.10 | ||||||||
| Molecular_name | T08G5.10 | ||||||||
| T08G5.10.1 | |||||||||
| CE25109 | |||||||||
| Other_name | met-II | Accession_evidence | EMBL | X53245 | |||||
| D17365 | |||||||||
| CELE_T08G5.10 | Accession_evidence | NDB | BX284605 | ||||||
| Public_name | mtl-2 | ||||||||
| DB_info | Database | AceView | gene | 5O498 | |||||
| WormQTL | gene | WBGene00003474 | |||||||
| WormFlux | gene | WBGene00003474 | |||||||
| NDB | locus_tag | CELE_T08G5.10 | |||||||
| NCBI | gene | 179899 | |||||||
| RefSeq | protein | NM_074081.9 | |||||||
| SwissProt | UniProtAcc | P17512 | |||||||
| UniProt_GCRP | UniProtAcc | P17512 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:32 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | mtl | ||||||||
| Allele (15) | |||||||||
| Legacy_information | [C.elegansII] NMK. Encodes 63 aa metallothionein; accumulates after exposure to CdCl2. mtl-1:lacZ expressed in intestine after cadmium treatment or heat shock. [Freedman et al. 1993] | ||||||||
| Strain | WBStrain00005079 | ||||||||
| WBStrain00005080 | |||||||||
| WBStrain00005081 | |||||||||
| WBStrain00005101 | |||||||||
| WBStrain00040877 | |||||||||
| WBStrain00035525 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00039557 | ||||||||
| 00039558 | |||||||||
| 00106045 | |||||||||
| 00106046 | |||||||||
| 00106267 | |||||||||
| 00106268 | |||||||||
| Ortholog (8) | |||||||||
| Structured_description | Concise_description | mtl-2 encodes one of two C. elegans metallothioneins, small, cysteine-rich, metal-binding proteins; MTL-2 functions in metal detoxification and homeostasis and stress adaptation; in addition, mtl-2 plays a role in regulating growth and fertility; mtl-2 expression is induced in larval and adult intestinal cells following exposure to cadmium or heat shock; MTL-2 intestinal expression is dependent upon ELT-2, an intestine-specific GATA-type transcription factor; mtl-2 is downregulated by DAF-16 in daf-2 mutants. | Paper_evidence | WBPaper00001688 | |||||
| WBPaper00003700 | |||||||||
| WBPaper00004299 | |||||||||
| WBPaper00004381 | |||||||||
| WBPaper00005295 | |||||||||
| WBPaper00005976 | |||||||||
| WBPaper00028866 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 07 May 2007 00:00:00 | ||||||||
| Automated_description | Enables cadmium ion binding activity and zinc ion binding activity. Involved in response to cadmium ion and response to heat. Expressed in intestinal cell and intestine. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | T08G5.10 | |||||||
| Corresponding_transcript | T08G5.10.1 | ||||||||
| Other_sequence | CBC00932_1 | ||||||||
| CBC01514_2 | |||||||||
| FD517649.1 | |||||||||
| CBC01514_1 | |||||||||
| CJC01860_1 | |||||||||
| CSC00487_1 | |||||||||
| FD517704.1 | |||||||||
| Associated_feature | WBsf653359 | ||||||||
| WBsf919637 | |||||||||
| WBsf919638 | |||||||||
| WBsf982357 | |||||||||
| WBsf982358 | |||||||||
| WBsf234895 | |||||||||
| Experimental_info | RNAi_result (11) | ||||||||
| Expr_pattern | Expr1380 | ||||||||
| Expr1509 | |||||||||
| Expr3079 | |||||||||
| Expr1020789 | |||||||||
| Expr1156496 | |||||||||
| Expr2013808 | |||||||||
| Expr2032048 | |||||||||
| Drives_construct (15) | |||||||||
| Construct_product | WBCnstr00007972 | ||||||||
| WBCnstr00007973 | |||||||||
| WBCnstr00011119 | |||||||||
| WBCnstr00036093 | |||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (257) | |||||||||
| Interaction | WBInteraction000003268 | ||||||||
| WBInteraction000009004 | |||||||||
| WBInteraction000009006 | |||||||||
| WBInteraction000029490 | |||||||||
| WBInteraction000126581 | |||||||||
| WBInteraction000165161 | |||||||||
| WBInteraction000177183 | |||||||||
| WBInteraction000309931 | |||||||||
| WBInteraction000343644 | |||||||||
| WBInteraction000428184 | |||||||||
| WBInteraction000436465 | |||||||||
| WBInteraction000453220 | |||||||||
| WBInteraction000504691 | |||||||||
| WBInteraction000504897 | |||||||||
| WBInteraction000521694 | |||||||||
| WBInteraction000524081 | |||||||||
| WBInteraction000524534 | |||||||||
| WBInteraction000524545 | |||||||||
| WBInteraction000524569 | |||||||||
| WBInteraction000524570 | |||||||||
| WBInteraction000536181 | |||||||||
| WBInteraction000536182 | |||||||||
| WBInteraction000536183 | |||||||||
| WBInteraction000536184 | |||||||||
| WBInteraction000541472 | |||||||||
| WBInteraction000541474 | |||||||||
| WBInteraction000541475 | |||||||||
| WBInteraction000541478 | |||||||||
| WBInteraction000541481 | |||||||||
| WBInteraction000541486 | |||||||||
| WBInteraction000541489 | |||||||||
| WBInteraction000541492 | |||||||||
| WBInteraction000541494 | |||||||||
| WBInteraction000541497 | |||||||||
| WBInteraction000542518 | |||||||||
| WBInteraction000542657 | |||||||||
| WBInteraction000542660 | |||||||||
| WBInteraction000549494 | |||||||||
| WBInteraction000549495 | |||||||||
| WBProcess | WBbiopr:00000039 | ||||||||
| WBbiopr:00000050 | |||||||||
| WBbiopr:00000053 | |||||||||
| WBbiopr:00000096 | |||||||||
| Map_info | Map | V | Position | 6.07164 | Error | 0.009738 | |||
| Positive | Positive_clone | CR#MT2 | |||||||
| T08G5 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||||
| Mapping_data | Multi_point | 4288 | |||||||
| 4500 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (74) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
