lin-9 encodes two novel proteins that are conserved amongst C. elegans, Drosophila, plants, and vertebrates; lin-9 activity is required redundantly with activity of the synMuv A genes, such as lin-8, for negative regulation of the RTK/Ras-mediated signal transduction pathway that controls vulval development; in addition, lin-9 activity is required non-redundantly for hermaphrodite gonadal sheath cell development (and thus, reproduction), as well as for development of the male reproductive system including the male sensory rays and spicules.
Predicted to enable DNA binding activity. Involved in embryo development; male sex differentiation; and regulation of multicellular organismal development. Part of DRM complex. Is an ortholog of human LIN9 (lin-9 DREAM MuvB core complex component).