WormBase Tree Display for Gene: WBGene00000535

WBGene00000535 SMap: S_parent: Sequence: K08B4
  Identity: Version: 2
    Name: CGC_name: cpi-1 Paper_evidence: WBPaper00026724
            WBPaper00005846
            WBPaper00024997
          Person_evidence: WBPerson4368
            WBPerson390
      Sequence_name: K08B4.6
      Molecular_name: K08B4.6
        K08B4.6.1
        CE18035
      Other_name: cli-2
        CELE_K08B4.6 Accession_evidence: NDB BX284604
      Public_name: cpi-1
    DB_info: Database: AceView gene 4G858
        WormQTL gene WBGene00000535
        WormFlux gene WBGene00000535
        NDB locus_tag CELE_K08B4.6
        Panther gene CAEEL|WormBase=WBGene00000535|UniProtKB=G5EDZ9
          family PTHR46186
        NCBI gene 177372
        RefSeq protein NM_068514.6
        SwissProt UniProtAcc G5EDZ9
        UniProt_GCRP UniProtAcc G5EDZ9
        OMIM gene 601891
            604312
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:21 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 04 Jan 2006 11:25:27 WBPerson2970 Name_change: CGC_name: cpi-1
                Other_name: cli-2
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: cpi
    Allele (20)
    Strain: WBStrain00031872
      WBStrain00054919
    RNASeq_FPKM (74)
    GO_annotation: 00015098
      00015099
      00015100
      00015101
      00015102
      00015103
      00015104
      00015105
      00015106
      00107561
    Ortholog (73)
    Paralog: WBGene00000534 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00016523 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00023486 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: cpi-1 encodes a homolog of cysteine protease inhibitors (cystatins); cpi-1 is at least superficially dispensable for viability and gross morphology. Paper_evidence: WBPaper00005654
            WBPaper00012890
          Curator_confirmed: WBPerson567
          Date_last_updated: 16 Jul 2007 00:00:00
      Automated_description: Enables cysteine-type endopeptidase inhibitor activity. Predicted to be located in cytoplasm; extracellular space; and vesicle. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; CST3-related cerebral amyloid angiopathy; artery disease (multiple); and autoimmune disease of the nervous system (multiple). Is an ortholog of human CST1 (cystatin SN); CST3 (cystatin C); and CST4 (cystatin S). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model (17)
  Molecular_info: Corresponding_CDS: K08B4.6
    Corresponding_transcript: K08B4.6.1
    Other_sequence (14)
    Associated_feature: WBsf651835
      WBsf230135
  Experimental_info: RNAi_result: WBRNAi00089361 Inferred_automatically: RNAi_primary
      WBRNAi00034106 Inferred_automatically: RNAi_primary
      WBRNAi00089116 Inferred_automatically: RNAi_primary
      WBRNAi00089348 Inferred_automatically: RNAi_primary
      WBRNAi00050231 Inferred_automatically: RNAi_primary
      WBRNAi00016775 Inferred_automatically: RNAi_primary
    Expr_pattern (4)
    Drives_construct: WBCnstr00037466
    Construct_product: WBCnstr00037466
    Microarray_results (16)
    Expression_cluster (307)
    Interaction: WBInteraction000030121
      WBInteraction000103528
      WBInteraction000109130
      WBInteraction000119320
      WBInteraction000124224
      WBInteraction000133413
      WBInteraction000135281
      WBInteraction000135302
      WBInteraction000137045
      WBInteraction000137529
      WBInteraction000137929
      WBInteraction000140673
      WBInteraction000140965
      WBInteraction000142632
      WBInteraction000144130
      WBInteraction000145887
      WBInteraction000146430
      WBInteraction000147340
      WBInteraction000147841
      WBInteraction000149425
      WBInteraction000150115
      WBInteraction000151100
      WBInteraction000151315
      WBInteraction000159639
      WBInteraction000160098
      WBInteraction000160115
      WBInteraction000160747
      WBInteraction000161425
      WBInteraction000161945
      WBInteraction000163673
      WBInteraction000167995
      WBInteraction000170191
      WBInteraction000171220
      WBInteraction000171436
      WBInteraction000174753
      WBInteraction000175927
      WBInteraction000176082
      WBInteraction000177903
      WBInteraction000180256
      WBInteraction000181938
      WBInteraction000181993
      WBInteraction000183326
      WBInteraction000187867
      WBInteraction000188168
      WBInteraction000188614
      WBInteraction000188709
      WBInteraction000190125
      WBInteraction000194022
      WBInteraction000194671
      WBInteraction000195633
      WBInteraction000195834
      WBInteraction000197371
      WBInteraction000198617
      WBInteraction000198695
      WBInteraction000198781
      WBInteraction000198909
      WBInteraction000200572
      WBInteraction000203368
      WBInteraction000203496
      WBInteraction000204661
      WBInteraction000206197
      WBInteraction000206494
      WBInteraction000209636
      WBInteraction000211130
      WBInteraction000213784
      WBInteraction000214028
      WBInteraction000214937
      WBInteraction000216303
      WBInteraction000218914
      WBInteraction000219758
      WBInteraction000221071
      WBInteraction000222237
      WBInteraction000222637
      WBInteraction000225477
      WBInteraction000230837
      WBInteraction000231719
      WBInteraction000232270
      WBInteraction000232563
      WBInteraction000233652
      WBInteraction000234721
      WBInteraction000240292
      WBInteraction000240866
      WBInteraction000242700
      WBInteraction000244132
      WBInteraction000244272
      WBInteraction000244460
      WBInteraction000247127
      WBInteraction000247202
      WBInteraction000250283
      WBInteraction000251341
      WBInteraction000251375
      WBInteraction000253569
      WBInteraction000254132
      WBInteraction000256165
      WBInteraction000256800
      WBInteraction000263179
      WBInteraction000264679
      WBInteraction000264720
      WBInteraction000265183
      WBInteraction000266235
      WBInteraction000266312
      WBInteraction000271462
      WBInteraction000274040
      WBInteraction000281317
      WBInteraction000287691
      WBInteraction000292372
      WBInteraction000293179
      WBInteraction000300526
      WBInteraction000302154
      WBInteraction000304890
      WBInteraction000305810
      WBInteraction000305975
      WBInteraction000306833
      WBInteraction000308709
      WBInteraction000309543
      WBInteraction000312410
      WBInteraction000313338
      WBInteraction000314106
      WBInteraction000317485
      WBInteraction000321513
      WBInteraction000322705
      WBInteraction000325181
      WBInteraction000328095
      WBInteraction000332891
      WBInteraction000336083
      WBInteraction000337145
      WBInteraction000337959
      WBInteraction000341601
      WBInteraction000342523
      WBInteraction000342569
      WBInteraction000344994
      WBInteraction000349516
      WBInteraction000351451
      WBInteraction000352206
      WBInteraction000352928
      WBInteraction000354447
      WBInteraction000354865
      WBInteraction000355211
      WBInteraction000361583
      WBInteraction000365421
      WBInteraction000370005
      WBInteraction000370287
      WBInteraction000370904
      WBInteraction000373027
      WBInteraction000374288
      WBInteraction000376334
      WBInteraction000377869
      WBInteraction000381137
      WBInteraction000382066
      WBInteraction000389282
      WBInteraction000395683
      WBInteraction000398045
      WBInteraction000398168
      WBInteraction000399412
      WBInteraction000407630
      WBInteraction000415095
      WBInteraction000417159
      WBInteraction000417785
      WBInteraction000421893
      WBInteraction000421967
      WBInteraction000424551
      WBInteraction000425115
      WBInteraction000427529
      WBInteraction000431935
      WBInteraction000435836
      WBInteraction000437656
      WBInteraction000439837
      WBInteraction000441557
      WBInteraction000442451
      WBInteraction000442463
      WBInteraction000442691
      WBInteraction000443685
      WBInteraction000444502
      WBInteraction000445319
      WBInteraction000447089
      WBInteraction000452549
      WBInteraction000455367
      WBInteraction000458114
      WBInteraction000461405
      WBInteraction000461720
      WBInteraction000461897
      WBInteraction000502620
      WBInteraction000548399
      WBInteraction000549635
      WBInteraction000552021
      WBInteraction000553923
      WBInteraction000557088
      WBInteraction000557860
      WBInteraction000567950
      WBInteraction000579897
  Map_info: Map: IV Position: 2.96435 Error: 0.003526
    Positive: Positive_clone: K08B4 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4900
    Pseudo_map_position
  Reference (13)
  Remark: Sequence connection from [Hashmi S, Lustigan S], [krb 020711]
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
    cpi-1 is also an other_name of cpin-1 (WBGene000000775) Person_evidence: WBPerson531
  Method: Gene