WormBase Tree Display for Gene: WBGene00000525
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| WBGene00000525 | Evidence | Person_evidence | WBPerson765 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | T05A10 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | clc-4 | |||||||
| Sequence_name | T05A10.2 | ||||||||
| Molecular_name | T05A10.2 | ||||||||
| T05A10.2.1 | |||||||||
| CE03634 | |||||||||
| Other_name | CELE_T05A10.2 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | clc-4 | ||||||||
| DB_info | Database | AceView | gene | XL402 | |||||
| WormQTL | gene | WBGene00000525 | |||||||
| WormFlux | gene | WBGene00000525 | |||||||
| NDB | locus_tag | CELE_T05A10.2 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00000525|UniProtKB=Q22191 | |||||||
| family | PTHR37446 | ||||||||
| NCBI | gene | 188095 | |||||||
| RefSeq | protein | NM_077399.2 | |||||||
| TREEFAM | TREEFAM_ID | TF316995 | |||||||
| TrEMBL | UniProtAcc | Q22191 | |||||||
| UniProt_GCRP | UniProtAcc | Q22191 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:21 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | clc | ||||||||
| Allele (14) | |||||||||
| Strain | WBStrain00036940 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00074466 | ||||||||
| 00074467 | |||||||||
| Ortholog (22) | |||||||||
| Paralog | WBGene00000522 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||||
| Structured_description | Concise_description | clc-4 encodes a claudin homolog that may be required for normal cohesion of apical junctions in epithelia; CLC-4 is worm-specific, with obvious homologs only in C. elegans; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water. | Paper_evidence | WBPaper00004961 | |||||
| WBPaper00005946 | |||||||||
| WBPaper00005975 | |||||||||
| WBPaper00012856 | |||||||||
| WBPaper00018356 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to be involved in epithelial cell-cell adhesion. Predicted to be located in membrane. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed (2) | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | T05A10.2 | |||||||
| Corresponding_transcript | T05A10.2.1 | ||||||||
| Other_sequence | CRC02181_1 | ||||||||
| CJC06228_1 | |||||||||
| CR05828 | |||||||||
| Associated_feature | WBsf1006818 | ||||||||
| WBsf237891 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00112618 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00035160 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00018171 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00052432 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1023488 | ||||||||
| Expr1156053 | |||||||||
| Expr2010044 | |||||||||
| Expr2028285 | |||||||||
| Drives_construct | WBCnstr00037474 | ||||||||
| Construct_product | WBCnstr00037474 | ||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (71) | |||||||||
| Interaction | WBInteraction000114366 | ||||||||
| WBInteraction000117706 | |||||||||
| WBInteraction000120621 | |||||||||
| WBInteraction000133826 | |||||||||
| WBInteraction000133970 | |||||||||
| WBInteraction000136805 | |||||||||
| WBInteraction000138623 | |||||||||
| WBInteraction000140914 | |||||||||
| WBInteraction000143941 | |||||||||
| WBInteraction000157201 | |||||||||
| WBInteraction000162057 | |||||||||
| WBInteraction000171084 | |||||||||
| WBInteraction000177756 | |||||||||
| WBInteraction000185221 | |||||||||
| WBInteraction000192806 | |||||||||
| WBInteraction000202443 | |||||||||
| WBInteraction000202776 | |||||||||
| WBInteraction000208106 | |||||||||
| WBInteraction000209891 | |||||||||
| WBInteraction000219980 | |||||||||
| WBInteraction000220406 | |||||||||
| WBInteraction000225463 | |||||||||
| WBInteraction000234328 | |||||||||
| WBInteraction000235888 | |||||||||
| WBInteraction000238140 | |||||||||
| WBInteraction000241322 | |||||||||
| WBInteraction000249657 | |||||||||
| WBInteraction000253796 | |||||||||
| WBInteraction000267327 | |||||||||
| WBInteraction000281507 | |||||||||
| WBInteraction000292036 | |||||||||
| WBInteraction000297034 | |||||||||
| WBInteraction000300594 | |||||||||
| WBInteraction000301780 | |||||||||
| WBInteraction000310657 | |||||||||
| WBInteraction000315586 | |||||||||
| WBInteraction000338378 | |||||||||
| WBInteraction000341523 | |||||||||
| WBInteraction000345924 | |||||||||
| WBInteraction000349272 | |||||||||
| WBInteraction000350783 | |||||||||
| WBInteraction000356175 | |||||||||
| WBInteraction000358149 | |||||||||
| WBInteraction000360461 | |||||||||
| WBInteraction000361182 | |||||||||
| WBInteraction000365498 | |||||||||
| WBInteraction000367766 | |||||||||
| WBInteraction000370210 | |||||||||
| WBInteraction000390121 | |||||||||
| WBInteraction000395884 | |||||||||
| WBInteraction000397699 | |||||||||
| WBInteraction000399663 | |||||||||
| WBInteraction000409097 | |||||||||
| WBInteraction000411004 | |||||||||
| WBInteraction000422749 | |||||||||
| WBInteraction000444362 | |||||||||
| WBInteraction000444557 | |||||||||
| WBInteraction000453452 | |||||||||
| Map_info | Map | X | Position | 2.52829 | Error | 0.004316 | |||
| Positive | Positive_clone | T05A10 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00005946 | ||||||||
| WBPaper00013424 | |||||||||
| WBPaper00013425 | |||||||||
| WBPaper00018356 | |||||||||
| WBPaper00039831 | |||||||||
| Remark | Sequence connection from [Asano A, Tsukita S] | ||||||||
| Name exchange requested by Dr. Asano: clc-2 = C01C10.1 and clc-4 = T05A10.2 | Person_evidence | WBPerson765 | |||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
