WormBase Tree Display for Gene: WBGene00005018
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WBGene00005018 | SMap | S_parent | Sequence | F23H12 | |||
---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||
Name | CGC_name | sqt-3 | Person_evidence | WBPerson153 | |||
Sequence_name | F23H12.4 | ||||||
Molecular_name | F23H12.4a | ||||||
F23H12.4a.1 | |||||||
CE05707 | |||||||
F23H12.4b | |||||||
CE46560 | |||||||
F23H12.4b.1 | |||||||
Other_name | col-1 | ||||||
dpy-15 | |||||||
rol-4 | Paper_evidence | WBPaper00024637 | |||||
Person_evidence | WBPerson261 | ||||||
Rol | |||||||
CELE_F23H12.4 | Accession_evidence | NDB | BX284605 | ||||
Public_name | sqt-3 | ||||||
DB_info | Database | AceView | gene | 5M833 | |||
WormQTL | gene | WBGene00005018 | |||||
WormFlux | gene | WBGene00005018 | |||||
NDB | locus_tag | CELE_F23H12.4 | |||||
Panther | gene | CAEEL|WormBase=WBGene00005018|UniProtKB=P08124 | |||||
family | PTHR24637 | ||||||
NCBI | gene | 179693 | |||||
RefSeq | protein | NM_001269484.3 | |||||
NM_001269483.3 | |||||||
SwissProt | UniProtAcc | P08124 | |||||
TrEMBL | UniProtAcc | H2L2C4 | |||||
UniProt_GCRP | UniProtAcc | P08124 | |||||
Species | Caenorhabditis elegans | ||||||
History | Version_change (2) | ||||||
Acquires_merge | WBGene00004396 | ||||||
Status | Live | ||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | sqt | ||||||
Reference_allele | WBVar00242688 | ||||||
Allele (64) | |||||||
Possibly_affected_by | WBVar02157913 | ||||||
WBVar02157914 | |||||||
WBVar02157915 | |||||||
WBVar02157916 | |||||||
WBVar02157917 | |||||||
Legacy_information | sc63ts : homozygotes at 25x are non-roller dumpy heterozygotes sc63/+ are non-dumpy left-handed roller in adult high penetrance deformed tail at 25x. ES3 ME0 (25x). At 15x slightly dumpy. NA > 8 (sc80ts (resembles sc63) e24sd ts (pka dpy-15 : dumpy inviable at 25x e24/+ dumpy at 25x) etc.). | ||||||
See sqt-3. | |||||||
See also e24, e2117 | |||||||
[C.elegansII] sc63ts,sd : homozygotes at 25C are non-roller dumpy, heterozygotes sc63/+ are non-dumpy left-handed roller in adult; high penetrance deformed tail at 25C. ES3 ME0 (25C). At 15C slightly dumpy. OA3: sc80ts (resembles sc63), e24sd,ts (pka dpy-15, dumpy inviable at 25C, e24/+ dumpy at 25C, sometimes Lon at15C), sc42 (recessive left roller), e2117ts (extreme dumpy early larval lethal at 25C). Cloned: encodes 295 aa collagen (pka col-1), dpy-13 family; mutations all missense; expressed at each larval stage, 4 - 2.5 hours before lethargus. [Kramer et al. 1982; Keyl et al. 1994; IA] | |||||||
sc8 : adults and L4 larvae left-handed rollers. ES3 (adult) ME2. NA3 (b238ts : at 25x rolls only in adult at 16x wildtype). | |||||||
[C.elegansII] sc8 : adults and L4 larvae left-handed rollers. ES3 (adult) ME2. OA2: b238ts (at 25C rolls only in adult, WT at 16C). [Cox et al. 1980] | |||||||
Strain (23) | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation | 00022225 | ||||||
00022226 | |||||||
00022227 | |||||||
00036922 | |||||||
00036923 | |||||||
00036924 | |||||||
00036925 | |||||||
00036926 | |||||||
00108198 | |||||||
Ortholog (28) | |||||||
Paralog (163) | |||||||
Structured_description | Concise_description | sqt-3 encodes a cuticle collagen; during development, sqt-3 activity is essential for viability and normal body morphology; genetic and expression studies indicate that SQT-3 is a cuticle component at all stages of development and that SQT-3 likely forms higher order cuticular structures with the DPY-17 cuticular collagen, both of which are candidate substrates for the DPY-31 procollagen C-proteinase. | Paper_evidence | WBPaper00000906 | |||
WBPaper00000927 | |||||||
WBPaper00002030 | |||||||
WBPaper00024637 | |||||||
WBPaper00027067 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
Date_last_updated | 27 Mar 2007 00:00:00 | ||||||
Automated_description | Predicted to be a structural constituent of cuticle. Involved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle. Located in collagen and cuticulin-based cuticle extracellular matrix. Expressed in hypodermis. | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS292 version of WormBase | ||||||
Date_last_updated | 24 Apr 2024 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | F23H12.4a | |||||
F23H12.4b | |||||||
Corresponding_transcript | F23H12.4a.1 | ||||||
F23H12.4b.1 | |||||||
Other_sequence (112) | |||||||
Associated_feature (12) | |||||||
Experimental_info (9) | |||||||
Map_info | Map | V | Position | 4.00808 | Error | 0.002342 | |
Well_ordered | |||||||
Positive | Positive_clone | F23H12 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
ZC348 | |||||||
Mapping_data (3) | |||||||
Landmark_gene | |||||||
Reference (159) | |||||||
Method | Gene |