WormBase Tree Display for Gene: WBGene00003254
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| WBGene00003254 | SMap | S_parent | Sequence | R07E4 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | mig-23 | Person_evidence | WBPerson261 | |||||
| Sequence_name | R07E4.4 | ||||||||
| Molecular_name | R07E4.4 | ||||||||
| R07E4.4.1 | |||||||||
| CE28748 | |||||||||
| Other_name | CELE_R07E4.4 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | mig-23 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:31 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | mig | ||||||||
| Allele (39) | |||||||||
| Legacy_information | [Nishiwaki K] Abnormal migration of DTC cells: these fail to migrate along dorsal muscles, and move erratically on the lateral hypodermal cells. | ||||||||
| Strain | WBStrain00002949 | ||||||||
| WBStrain00028704 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (33) | |||||||||
| Contained_in_operon | CEOPX068 | ||||||||
| Ortholog (37) | |||||||||
| Paralog | WBGene00016380 | Caenorhabditis elegans | From_analysis | Inparanoid_8 | |||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00010697 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | mig-23 encodes a nucleoside diphosphatase (NDPase); during larval development, MIG-23 activity is required, in body wall muscle cells, for proper dorsalward migration of the gonadal distal tip cells (DTCs) and gonad morphogenesis via regulation of MIG-17 N-glycosylation; animals lacking MIG-23 exhibit weaker UDP-, ADP-, and GDP-hydrolysing activity and when expressed in yeast lacking apyrase genes, MIG-23 can rescue NDPase activity; when expressed in body wall muscle under the control of the unc-54 promoter, MIG-23 rescues DTC migration defects and shows a punctate cytoplasmic expression pattern similar to that of Golgi enzymes. | Paper_evidence | WBPaper00006309 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 14 May 2007 00:00:00 | ||||||||
| Automated_description | Enables ADP phosphatase activity; GDP phosphatase activity; and UDP phosphatase activity. Involved in several processes, including gonad morphogenesis; positive regulation of protein glycosylation; and ribonucleoside diphosphate catabolic process. Located in cytoplasm. Expressed in head and tail. Is an ortholog of human ENTPD4 (ectonucleoside triphosphate diphosphohydrolase 4) and ENTPD7 (ectonucleoside triphosphate diphosphohydrolase 7). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | R07E4.4 | |||||||
| Corresponding_transcript | R07E4.4.1 | ||||||||
| Other_sequence | MJC04075_1 | ||||||||
| HG04803 | |||||||||
| MJ04502 | |||||||||
| CBC16741_1 | |||||||||
| MCC04672_1 | |||||||||
| BXC05465_1 | |||||||||
| JI168291.1 | |||||||||
| HGC11764_1 | |||||||||
| MC04508 | |||||||||
| Oden_isotig14872 | |||||||||
| Associated_feature | WBsf1005433 | ||||||||
| WBsf237416 | |||||||||
| WBsf237417 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00051475 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00017554 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00034711 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00110309 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00051474 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr6477 | ||||||||
| Expr1027842 | |||||||||
| Expr1031544 | |||||||||
| Expr1155160 | |||||||||
| Expr2013569 | |||||||||
| Expr2031802 | |||||||||
| Drives_construct | WBCnstr00003455 | ||||||||
| WBCnstr00036159 | |||||||||
| Construct_product | WBCnstr00036159 | ||||||||
| Antibody | WBAntibody00000704 | ||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (109) | |||||||||
| Interaction (11) | |||||||||
| Anatomy_function | WBbtf0250 | ||||||||
| WBbtf0251 | |||||||||
| WBbtf0252 | |||||||||
| WBbtf0253 | |||||||||
| WBbtf0254 | |||||||||
| WBbtf1051 | |||||||||
| Map_info | Map | X | Position | -4.0272 | Error | 0.011949 | |||
| Positive | Positive_clone | R07E4 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 3698 | |||||||
| 4456 | |||||||||
| Reference (13) | |||||||||
| Method | Gene |
