WormBase Tree Display for Gene: WBGene00002827
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WBGene00002827 | SMap | S_parent | Sequence | C29E6 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | let | ||||||
Laboratory | BC | ||||||
Reference_allele | WBVar00242198 | ||||||
Allele (88) | |||||||
Legacy_information | Early larval e | ||||||
Lethal arrest stage is late L1 to early L2. | |||||||
See also s1733 | |||||||
[Marra MA] Developmental arrest stage 7 days after egg lay at room temperature: s2270 homozygote = L2 larva with a vacuole anterior to lower pharyngeal bulb. s2270/sDf10 = L1 larva with a vacuole anterior to lower pharyngeal bulb. | |||||||
[Marra MA] Developmental arrest stage 7 days after egg lay at room temperature: s2377 homozygote = Sterile adult. s2377/sDf10 = L2 larva with a vacuole anterior to lower pharyngeal bulb | |||||||
[C.elegansII] s1733 : early larval lethal, arrest stage is late L1 to early L2; cystic excretory canals. OA2: s2270 (homozygote arrests L2 with vacuole anterior to posterior pharyngeal bulb,hemizygote arrests L1), s2377 (homozygote sterile adult, hemizygote arrests L2). Cloned: encodes predicted 694 aa secreted protein, with features characteristic of mucin glycoproteins. [Jones and Baillie 1995; BC; NJ] | |||||||
Complementation_data | [Marra MA] s2270 fails to complement let-653(s1733). | ||||||
[Marra MA] s2377 fails to complement let-653(s2270). s2377 complements let-653(s1733). | |||||||
Strain | WBStrain00000664 | ||||||
WBStrain00051077 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (21) | |||||||
Ortholog (33) | |||||||
Paralog (14) | |||||||
Structured_description | Concise_description | let-653 encodes a mucin-like protein similar to the highly glycosylated mucins secreted by the apical surface of epithelia and believed to provide a protective barrier to exposed cellular surfaces; LET-653 is required for viability, locomotion, and for maintaining the tubular epithelial structure of the excretory cell canals. | Paper_evidence | WBPaper00001522 | |||
WBPaper00002328 | |||||||
WBPaper00005485 | |||||||
WBPaper00005654 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||
Automated_description | A structural constituent of cuticle. Involved in several processes, including cuticle pattern formation; embryonic ectodermal digestive tract morphogenesis; and regulation of developmental process. Located in apical plasma membrane; extracellular space; and supramolecular fiber. Expressed in excretory duct cell; excretory socket cell; rectal epithelial cell; and vulval cell. | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | C29E6.1a | |||||
C29E6.1b | |||||||
C29E6.1c | |||||||
Corresponding_CDS_history | C29E6.1:wp131 | ||||||
C29E6.1a:wp167 | |||||||
Corresponding_transcript | C29E6.1a.1 | ||||||
C29E6.1b.1 | |||||||
C29E6.1c.1 | |||||||
Other_sequence (13) | |||||||
Associated_feature | WBsf660769 | ||||||
WBsf997988 | |||||||
WBsf997989 | |||||||
WBsf229216 | |||||||
Experimental_info | RNAi_result (18) | ||||||
Expr_pattern | Chronogram509 | ||||||
Expr5376 | |||||||
Expr13008 | |||||||
Expr13009 | |||||||
Expr15950 | |||||||
Expr1016864 | |||||||
Expr1031364 | |||||||
Expr1145484 | |||||||
Expr2013069 | |||||||
Expr2031301 | |||||||
Drives_construct | WBCnstr00002332 | ||||||
WBCnstr00036319 | |||||||
WBCnstr00038392 | |||||||
WBCnstr00039173 | |||||||
Construct_product (3) | |||||||
Microarray_results (28) | |||||||
Expression_cluster (220) | |||||||
Interaction (23) | |||||||
Map_info | Map | IV | Position | 5.36564 | Error | 0.003548 | |
Well_ordered | |||||||
Positive | Positive_clone | C29E6 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
C46F3 | |||||||
F47H9 | |||||||
ZK822 | |||||||
Mapping_data | Multi_point | 4854 | |||||
4821 | |||||||
5253 | |||||||
Pos_neg_data (29) | |||||||
Reference (36) | |||||||
Method | Gene |