WormBase Tree Display for Gene: WBGene00002222
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WBGene00002222 | Evidence | Paper_evidence | WBPaper00003466 | ||||
---|---|---|---|---|---|---|---|
SMap | S_parent | Sequence | F20C5 | ||||
Identity | Version | 3 | |||||
Name | CGC_name | klp-11 | Person_evidence | WBPerson589 | |||
Sequence_name | F20C5.2 | ||||||
Molecular_name (12) | |||||||
Other_name | krp95 | Accession_evidence | EMBL | AF149288 | |||
CELE_F20C5.2 | Accession_evidence | NDB | BX284604 | ||||
Public_name | klp-11 | ||||||
DB_info | Database | AceView | gene | 4J520 | |||
WormQTL | gene | WBGene00002222 | |||||
WormFlux | gene | WBGene00002222 | |||||
NDB | locus_tag | CELE_F20C5.2 | |||||
Panther | gene | CAEEL|WormBase=WBGene00002222|UniProtKB=Q19633 | |||||
family | PTHR24115 | ||||||
NCBI | gene | 177685 | |||||
RefSeq | protein | NM_001136383.3 | |||||
NM_001268401.2 | |||||||
NM_001136382.3 | |||||||
NM_001383153.2 | |||||||
TrEMBL | UniProtAcc | B3GWB6 | |||||
B3GWB7 | |||||||
Q19633 | |||||||
E5QCG4 | |||||||
UniProt_GCRP | UniProtAcc | Q19633 | |||||
OMIM | gene | 603754 | |||||
Species | Caenorhabditis elegans | ||||||
History (3) | |||||||
Status | Live | ||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | klp | ||||||
Allele (81) | |||||||
Legacy_information | [Siddiqui SS ] Predicted gene F20C5.2. Related to kinesin like protein by sequence similarity. | ||||||
Strain | WBStrain00002305 | ||||||
WBStrain00036431 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (20) | |||||||
Contained_in_operon | CEOP4609 | ||||||
CEOP5618 | |||||||
Ortholog (37) | |||||||
Paralog (19) | |||||||
Structured_description | Concise_description | klp-11 encodes a kinesin motor protein that functions as a subunit of C. elegans heterotrimeric kinesin-II; in vitro microtubule gliding assays demonstrate that purified kinesin-II and OSM-3, a homomeric kinesin-II motor, cooperatively generate movement similar to that seen along cilia lacking additional regulatory factors; antibodies to KLP-11 detect high intensity staining in the cilia of chemosensory neurons, with fainter staining detected in the dorsal and ventral nerve cords as well as motor commissures. | Paper_evidence | WBPaper00003466 | |||
WBPaper00004178 | |||||||
WBPaper00027116 | |||||||
WBPaper00028530 | |||||||
Curator_confirmed | WBPerson48 | ||||||
WBPerson1843 | |||||||
Date_last_updated | 13 Oct 2008 00:00:00 | ||||||
Automated_description | Enables microtubule motor activity. Involved in microtubule-based movement. Part of axonemal heterotrimeric kinesin-II complex. Expressed in amphid neurons; dorsal nerve cord; inner labial neurons; phasmid neurons; and ventral nerve cord. Human ortholog(s) of this gene implicated in retinitis pigmentosa 89. Is an ortholog of human KIF3B (kinesin family member 3B) and KIF3C (kinesin family member 3C). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model | DOID:0112146 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6320) | ||
Molecular_info | Corresponding_CDS | F20C5.2a | |||||
F20C5.2c | |||||||
F20C5.2d | |||||||
F20C5.2f | |||||||
Corresponding_CDS_history | F20C5.2:wp52 | ||||||
F20C5.2b:wp261 | |||||||
F20C5.2c:wp221 | |||||||
F20C5.2c:wp242 | |||||||
F20C5.2d:wp221 | |||||||
F20C5.2d:wp242 | |||||||
F20C5.2e:wp242 | |||||||
F20C5.2f:wp242 | |||||||
F20C5.2g:wp264 | |||||||
Corresponding_transcript | F20C5.2a.1 | ||||||
F20C5.2c.1 | |||||||
F20C5.2d.1 | |||||||
F20C5.2f.1 | |||||||
Other_sequence (22) | |||||||
Associated_feature (13) | |||||||
Experimental_info | RNAi_result | WBRNAi00013605 | Inferred_automatically | RNAi_primary | |||
WBRNAi00045087 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00000743 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00111057 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00031160 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Chronogram1483 | ||||||
Expr1271 | |||||||
Expr16079 | |||||||
Expr1015580 | |||||||
Expr1031301 | |||||||
Expr1149036 | |||||||
Expr2012955 | |||||||
Expr2031187 | |||||||
Drives_construct | WBCnstr00004390 | ||||||
WBCnstr00036376 | |||||||
Construct_product | WBCnstr00036376 | ||||||
Antibody | WBAntibody00000218 | ||||||
Microarray_results (8) | |||||||
Expression_cluster (165) | |||||||
Interaction (48) | |||||||
Map_info | Map | IV | Position | 3.96111 | Error | 0.00054 | |
Positive | Positive_clone | F20C5 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Mapping_data | Multi_point | 4465 | |||||
4592 | |||||||
Pseudo_map_position | |||||||
Reference (38) | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |