WormBase Tree Display for Gene: WBGene00011910
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WBGene00011910 | SMap | S_parent | Sequence | CHROMOSOME_IV | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | CGC_name | alg-3 | Paper_evidence | WBPaper00035890 | |||||
Person_evidence | WBPerson419 | ||||||||
Sequence_name | T22B3.2 | ||||||||
Molecular_name | T22B3.2a | ||||||||
T22B3.2a.1 | |||||||||
CE18277 | |||||||||
T22B3.2b | |||||||||
CE06488 | |||||||||
T22B3.2b.1 | |||||||||
T22B3.2b.2 | |||||||||
Other_name | CELE_T22B3.2 | Accession_evidence | NDB | BX284604 | |||||
Public_name | alg-3 | ||||||||
DB_info | Database | AceView | gene | 4M471 | |||||
WormQTL | gene | WBGene00011910 | |||||||
WormFlux | gene | WBGene00011910 | |||||||
NDB | locus_tag | CELE_T22B3.2 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00011910|UniProtKB=G5ED77 | |||||||
family | PTHR22891 | ||||||||
NCBI | gene | 178106 | |||||||
RefSeq | protein | NM_069817.5 | |||||||
NM_069816.3 | |||||||||
TREEFAM | TREEFAM_ID | TF101510 | |||||||
TrEMBL | UniProtAcc | G5ED77 | |||||||
G5EC94 | |||||||||
UniProt_GCRP | UniProtAcc | G5ED77 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 26 May 2004 16:54:53 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
2 | 23 Dec 2013 09:56:37 | WBPerson2970 | Name_change | CGC_name | alg-3 | ||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | alg | ||||||||
Allele (49) | |||||||||
Possibly_affected_by | WBVar02158850 | ||||||||
Strain | WBStrain00040479 | ||||||||
WBStrain00054822 | |||||||||
WBStrain00054838 | |||||||||
In_cluster | conserved_RDE-1_cluster | ||||||||
conserved_miRNA_siRNA_cluster | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation | 00011357 | ||||||||
00011358 | |||||||||
00011359 | |||||||||
00011360 | |||||||||
00013509 | |||||||||
00013510 | |||||||||
00013511 | |||||||||
00119114 | |||||||||
00119115 | |||||||||
Ortholog (49) | |||||||||
Paralog (22) | |||||||||
Structured_description | Concise_description | alg-3 encodes an Argonaute (AGO) protein that is a member of the AGO clade of Argonaute small RNA-binding proteins; together with its paralog, alg-4, alg-3 is required for normal brood sizes at elevated temperatures, specifically for the process of spermiogenesis in which spermatids are converted to mobile ameboid sperm; alg-3/4 is also required for accumulation of male germline-specific 26G-RNAs, suggesting that alg-3/4 mediate thermotolerant fertility via a 26G-RNA-mediated pathway; a GFP::ALG-3 rescuingfusion protein is expressed in germ cells during spermatogenesis and localizes to the cytoplasm and to P granules. | Paper_evidence | WBPaper00035890 | |||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 11 Feb 2010 00:00:00 | ||||||||
Automated_description | Predicted to enable RNA endonuclease activity and single-stranded RNA binding activity. Involved in spermatogenesis. Located in P granule. Expressed in germ line. | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | T22B3.2a | |||||||
T22B3.2b | |||||||||
Corresponding_transcript | T22B3.2a.1 | ||||||||
T22B3.2b.1 | |||||||||
T22B3.2b.2 | |||||||||
Other_sequence (50) | |||||||||
Associated_feature | WBsf997914 | ||||||||
WBsf1018247 | |||||||||
WBsf229198 | |||||||||
Experimental_info | RNAi_result | WBRNAi00019004 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00001900 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00053790 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr8896 | ||||||||
Expr8897 | |||||||||
Expr16403 | |||||||||
Expr1016112 | |||||||||
Expr1035254 | |||||||||
Expr1157341 | |||||||||
Expr2009290 | |||||||||
Expr2027527 | |||||||||
Drives_construct | WBCnstr00013590 | ||||||||
WBCnstr00030291 | |||||||||
Construct_product | WBCnstr00005928 | ||||||||
WBCnstr00013590 | |||||||||
WBCnstr00030291 | |||||||||
Regulate_expr_cluster | WBPaper00044616:alg-3-4_downregulated_gene | ||||||||
WBPaper00044616:alg-3-4_downregulated_protein | |||||||||
WBPaper00044616:alg-3-4_upregulated_gene | |||||||||
WBPaper00044616:alg-3-4_upregulated_protein | |||||||||
Microarray_results (23) | |||||||||
Expression_cluster (241) | |||||||||
Interaction (45) | |||||||||
Map_info | Map | IV | Position | 5.2246 | |||||
Positive | Positive_clone | T22B3 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Pseudo_map_position | |||||||||
Reference | WBPaper00003335 | ||||||||
WBPaper00004772 | |||||||||
WBPaper00028800 | |||||||||
WBPaper00033741 | |||||||||
WBPaper00035324 | |||||||||
WBPaper00035890 | |||||||||
WBPaper00038896 | |||||||||
WBPaper00039814 | |||||||||
WBPaper00044616 | |||||||||
WBPaper00045091 | |||||||||
WBPaper00046160 | |||||||||
WBPaper00047222 | |||||||||
WBPaper00056169 | |||||||||
WBPaper00058205 | |||||||||
WBPaper00058221 | |||||||||
WBPaper00058388 | |||||||||
WBPaper00060750 | |||||||||
WBPaper00061753 | |||||||||
WBPaper00061881 | |||||||||
WBPaper00062465 | |||||||||
WBPaper00062585 | |||||||||
WBPaper00063558 | |||||||||
WBPaper00063609 | |||||||||
WBPaper00063708 | |||||||||
WBPaper00063938 | |||||||||
WBPaper00064344 | |||||||||
WBPaper00065028 | |||||||||
WBPaper00065759 | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |