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WormBase Tree Display for Gene: WBGene00006529

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Name Class

WBGene00006529SMapS_parentSequenceC47B2
IdentityVersion1
NameCGC_nametba-2
Sequence_nameC47B2.3
Molecular_nameC47B2.3
C47B2.3.1
CE17563
C47B2.3.2
Other_nameAlpha-tubulinAccession_evidenceEMBLD14965
TUBA4B
mel-45Person_evidenceWBPerson399
CELE_C47B2.3Accession_evidenceNDBBX284601
Public_nametba-2
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:40WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classtba
Allele (42)
Legacy_information[C.elegansII] NMK. Encodes alpha tubulin. tba-2:lacZ expressed in touch cells, motor neurons and certain other neurons. [SQ]
[Mains PE] Dominant, temperature-sensitive maternal-effect lethal. Defective early cleavage divisions. Homozygous nonconditional maternal-effect lethal.
StrainWBStrain00008449
WBStrain00008455
WBStrain00008457
WBStrain00007877
RNASeq_FPKM (74)
GO_annotation (24)
Contained_in_operonCEOP1680
Ortholog (50)
Paralog (16)
Structured_descriptionConcise_descriptiontba-2 encodes an alpha-tubulin.Paper_evidenceWBPaper00004402
WBPaper00006395
Curator_confirmedWBPerson48
WBPerson1843
Date_last_updated08 Jan 2009 00:00:00
Automated_descriptionPredicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Involved in several processes, including centrosome localization; establishment of mitotic spindle orientation; and regulation of cytokinesis. Predicted to be located in cytoplasm and microtubule. Expressed in several structures, including body wall musculature; intestine; neurons; pharynx; and ventral nerve cord. Human ortholog(s) of this gene implicated in thrombocytopenia. Is an ortholog of human TUBA8 (tubulin alpha 8) and TUBAL3 (tubulin alpha like 3).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:1588Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12410)
Molecular_infoCorresponding_CDSC47B2.3
Corresponding_CDS_historyC47B2.3b:wp123
Corresponding_transcriptC47B2.3.1
C47B2.3.2
Other_sequence (137)
Associated_feature (11)
Experimental_infoRNAi_result (52)
Expr_pattern (11)
Drives_constructWBCnstr00009169
WBCnstr00012441
WBCnstr00039275
Construct_productWBCnstr00004942
WBCnstr00015886
WBCnstr00038427
Microarray_results (22)
Expression_cluster (205)
Interaction (289)
Map_infoMapIPosition16.7819Error0.095464
PositivePositive_cloneC47B2Inferred_automaticallyFrom sequence, transcript, pseudogene data
NW#A4B
Mapping_dataMulti_point5586
5686
ReferenceWBPaper00002176
WBPaper00002958
WBPaper00003414
WBPaper00004402
WBPaper00006059
WBPaper00006237
WBPaper00006310
WBPaper00010264
WBPaper00010342
WBPaper00010889
WBPaper00013420
WBPaper00015124
WBPaper00015440
WBPaper00015548
WBPaper00018880
WBPaper00019293
WBPaper00021779
WBPaper00023576
WBPaper00024200
WBPaper00024430
WBPaper00025044
WBPaper00025163
WBPaper00025587
WBPaper00026640
WBPaper00027197
WBPaper00027253
WBPaper00028423
WBPaper00028493
WBPaper00029197
WBPaper00029395
WBPaper00031224
WBPaper00031309
WBPaper00031555
WBPaper00032438
WBPaper00032497
WBPaper00036019
WBPaper00038491
WBPaper00042741
WBPaper00042743
WBPaper00044012
WBPaper00045213
WBPaper00046064
WBPaper00047395
WBPaper00048416
WBPaper00049531
WBPaper00049828
WBPaper00050344
WBPaper00051909
WBPaper00052008
WBPaper00052847
WBPaper00055090
WBPaper00059105
WBPaper00059214
WBPaper00061344
WBPaper00061394
WBPaper00063088
WBPaper00064947
RemarkSequence connection updated on advice of JAH (was previously connected to F26E4.8)
Sequence connection from [Gremke L, Culotti JG]
MethodGene