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WormBase Tree Display for Gene: WBGene00004768

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Name Class

WBGene00004768SMapS_parentSequenceF55A11
IdentityVersion2
NameCGC_namesel-11Person_evidenceWBPerson220
Sequence_nameF55A11.3
Molecular_nameF55A11.3
F55A11.3.1
CE05945
Other_namehrd-1
CELE_F55A11.3Accession_evidenceNDBBX284605
Public_namesel-11
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:36WBPerson1971EventImportedInitial conversion from geneace
205 Nov 2008 10:04:18WBPerson2970EventAcquires_mergeWBGene00010076
Name_changeSequence_nameF55A11.3
Other_namehrd-1
Acquires_mergeWBGene00010076
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classsel
Allele (38)
Legacy_information[Sundaram M] ar39 recessive suppressor of lin-12 hypomorph, and partial suppressor of glp-1 hypomorph; no effect on lin-12 amorph; no phenotype alone; probable gf mutation. NA2 (ar84).
[C.elegansII] ar39 : recessive suppressor of lin-12 hypomorph, and partial suppressor of glp-1 hypomorph; no effect on lin-12 amorph; no phenotype alone; probable gf mutation. OA1: ar84. [Sundaram and Greenwald 1993; GS]
StrainWBStrain00008018
WBStrain00037821
RNASeq_FPKM (74)
GO_annotation (12)
Contained_in_operonCEOP5300
Ortholog (33)
ParalogWBGene00009164Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00022471Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionsel-11 encodes an E3 ubiquitin ligase; sel-11 was identified in screens for mutations that suppress the egg-laying defective (Egl) phenotype of a hypomorphic lin-12 allele; sel-11 mutations also suppress the temperature-sensitive, maternal-effect embryonic lethality of a glp-1 partial loss-of-function allele; SEL-11 functions as an ER E3 ubiquitin ligase that plays a role in the unfolded protein response (UPR), as well as growth and development of the intestine and gonad.Paper_evidenceWBPaper00001828
WBPaper00030999
Curator_confirmedWBPerson1843
Date_last_updated14 Dec 2009 00:00:00
Automated_descriptionPredicted to enable metal ion binding activity and transferase activity. Involved in regulation of Notch signaling pathway and regulation of gene expression. Predicted to be located in cytoplasm. Is an ortholog of human SYVN1 (synoviolin 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF55A11.3
Corresponding_transcriptF55A11.3.1
Other_sequence (38)
Associated_featureWBsf661772
WBsf977300
WBsf232545
Experimental_infoRNAi_resultWBRNAi00093524Inferred_automaticallyRNAi_primary
WBRNAi00093502Inferred_automaticallyRNAi_primary
WBRNAi00093486Inferred_automaticallyRNAi_primary
WBRNAi00048409Inferred_automaticallyRNAi_primary
WBRNAi00093478Inferred_automaticallyRNAi_primary
WBRNAi00063625Inferred_automaticallyRNAi_primary
WBRNAi00093506Inferred_automaticallyRNAi_primary
WBRNAi00076478Inferred_automaticallyRNAi_primary
WBRNAi00093494Inferred_automaticallyRNAi_primary
WBRNAi00093149Inferred_automaticallyRNAi_primary
WBRNAi00032832Inferred_automaticallyRNAi_primary
Expr_patternExpr16446
Expr1020375
Expr1032362
Expr1152198
Expr2015729
Expr2033962
Drives_constructWBCnstr00037921
Construct_productWBCnstr00037921
Microarray_results (21)
Expression_cluster (90)
Interaction (77)
WBProcessWBbiopr:00000046
WBbiopr:00000076
Map_infoMapVPosition3.33455Error0.010731
PositivePositive_cloneF55A11Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point2806
2807
2808
2809
Reference (24)
Remarkfrom Sundaram & Greenwald 1993
MethodGene