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WormBase Tree Display for Gene: WBGene00000955

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Name Class

WBGene00000955SMapS_parentSequenceCHROMOSOME_V
IdentityVersion1
NameCGC_namedes-2Person_evidenceWBPerson95
Sequence_nameT26H10.1
Molecular_nameT26H10.1a
T26H10.1a.1
CE21208
T26H10.1b
CE47329
T26H10.1a.2
T26H10.1b.1
Other_nameacr-4
CELE_T26H10.1Accession_evidenceNDBBX284605
Public_namedes-2
DB_infoDatabaseAceViewgene5L894
WormQTLgeneWBGene00000955
WormFluxgeneWBGene00000955
NDBlocus_tagCELE_T26H10.1
PanthergeneCAEEL|WormBase=WBGene00000955|UniProtKB=O76554
familyPTHR18945
NCBIgene179574
RefSeqproteinNM_001392616.1
NM_001392615.1
SwissProtUniProtAccO76554
TrEMBLUniProtAccH9G2Y4
UniProt_GCRPUniProtAccO76554
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:22WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classdes
Allele (93)
Legacy_information[C.elegansII] Mutation acts as a suppressor of deg-3(u662). [Treinin & Chalfie 1995; TU]
StrainWBStrain00035046
WBStrain00035004
WBStrain00052612
RNASeq_FPKM (74)
GO_annotation (20)
Contained_in_operonCEOP5284
Ortholog (26)
Paralog (100)
Structured_descriptionConcise_descriptiondes-2 encodes an alpha subunit of nicotinic acetylcholine receptor (nAChR), predicted to be a ligand-gated ion channel regulating the fast action of acetylcholine at neuromuscular junctions and in the nervous system; DES-2 is coexpressed with and genetically interacts with DEG-3, which which it probably forms heteromultimers, and DES-2 falls into the 'DEG-3' class of nAChR subunits, probably unique to nematodes, which includes DEG-3, ACR-5, ACR-17, ACR-18 ACR-20, and ACR-23.Paper_evidenceWBPaper00003338
WBPaper00005223
Curator_confirmedWBPerson1843
WBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Located in plasma membrane. Expressed in AIY; ALA; IL2 neuron; and pm1.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDST26H10.1a
T26H10.1b
Corresponding_transcriptT26H10.1a.1
T26H10.1a.2
T26H10.1b.1
Other_sequence (52)
Associated_featureWBsf669382
WBsf669383
WBsf718402
WBsf1001346
WBsf1020446
WBsf1020447
Experimental_infoRNAi_resultWBRNAi00054226Inferred_automaticallyRNAi_primary
WBRNAi00102750Inferred_automaticallyRNAi_primary
WBRNAi00016518Inferred_automaticallyRNAi_primary
WBRNAi00027847Inferred_automaticallyRNAi_primary
WBRNAi00066378Inferred_automaticallyRNAi_primary
WBRNAi00019274Inferred_automaticallyRNAi_primary
WBRNAi00115934Inferred_automaticallyRNAi_primary
Expr_patternExpr627
Expr9116
Expr10074
Expr1014659
Expr1030593
Expr1157773
Expr1200287
Expr2010860
Expr2029098
Drives_construct (21)
Construct_productWBCnstr00006092
WBCnstr00006971
WBCnstr00037181
Microarray_resultsSMD_K03B8.10
SMD_T26H10.1
175827_at
193423_s_at
A_12_P102546
Aff_K03B8.10
GPL13394_WBGene00000955
GPL13914_T26H10.1
GPL14144_T26H10.1_1254-1313_0.941_6_C
GPL14144_T26H10.1_1545-1604_0.964_1_A
GPL14144_T26H10.1_1606-1665_0.948_4_B
GPL19516_CGZ0036963
GPL19516_CGZ0036964
GPL21109_T26H10.1a
GPL21109_T26H10.1b
GPL3518_CE21208
GPL8304_CE_WBGene00000955_A
GPL8673_T26H10_1P00649
GPL8673_T26H10_1P01101
GPL8673_T26H10_1P01484
GPL9450_T26H10.1
cea2.d.06009
Expression_cluster (150)
Interaction (13)
Map_infoMapVPosition3.09462Error0.004712
PositivePositive_cloneK03B8
T26H10Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4255
4490
Pseudo_map_position
Reference (41)
RemarkSequence K03B8.10 removed.No longer exists. gene at overlap with cosmid T26H10. [sdm 000917]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene