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WormBase Tree Display for Gene: WBGene00000881

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Name Class

WBGene00000881SMapS_parentSequenceF31C3
IdentityVersion2
NameCGC_namecyn-5Person_evidenceWBPerson466
Sequence_nameF31C3.1
Molecular_nameF31C3.1
F31C3.1.1
CE17730
Other_namecyp-5Person_evidenceWBPerson466
CELE_F31C3.1Accession_evidenceNDBBX284601
Public_namecyn-5
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:21WBPerson1971EventImportedInitial conversion from geneace
220 Sep 2004 16:20:03WBPerson1971Name_changeCGC_namecyp-5 -> cyn-5
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcyn
Allele (34)
Legacy_information[C.elegansII] NMK. Cyclophilin family, transspliced to SL1. Cosmid B0467. [TP]
StrainWBStrain00001607
WBStrain00002246
RNASeq_FPKM (74)
GO_annotation (15)
Contained_in_operonCEOP1776
Ortholog (40)
Paralog (18)
Structured_descriptionConcise_descriptioncyn-5 encodes a cyclophilin that is functional in vitro and is predicted to be a secreted protein that is structurally most similar to human cyclophilin B; expressed in the intestine.Paper_evidenceWBPaper00005482
WBPaper00026884
Curator_confirmedWBPerson48
WBPerson1843
Date_last_updated20 Mar 2007 00:00:00
Automated_descriptionEnables peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding. Located in cytoplasm. Expressed in intestine. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 9. Is an ortholog of human PPIB (peptidylprolyl isomerase B).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0110349Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:9255)
Molecular_infoCorresponding_CDSF31C3.1
Corresponding_transcriptF31C3.1.1
Other_sequence (187)
Associated_featureWBsf034267
WBsf649789
WBsf649790
WBsf665195
WBsf981150
WBsf220682
WBsf220683
WBsf220684
WBsf220685
WBsf220686
Experimental_infoRNAi_resultWBRNAi00045993Inferred_automaticallyRNAi_primary
WBRNAi00027818Inferred_automaticallyRNAi_primary
WBRNAi00024339Inferred_automaticallyRNAi_primary
WBRNAi00022706Inferred_automaticallyRNAi_primary
WBRNAi00024338Inferred_automaticallyRNAi_primary
WBRNAi00022705Inferred_automaticallyRNAi_primary
Expr_pattern (14)
Drives_constructWBCnstr00002446
WBCnstr00004345
WBCnstr00010562
WBCnstr00037225
Construct_productWBCnstr00010562
WBCnstr00037225
AntibodyWBAntibody00000560
Microarray_resultsSMD_F31C3.1
190460_s_at
A_12_P115485
A_12_P136085
Aff_F31C3.1
GPL13394_WBGene00000881
GPL13914_F31C3.1
GPL14144_F31C3.1_148-207_0.905_3_B
GPL14144_F31C3.1_227-286_0.700_37_C
GPL14144_F31C3.1_81-140_0.912_1_A
GPL19516_CGZ0019051
GPL21109_F31C3.1
GPL3518_CE17730
GPL8304_CE_WBGene00000881_A
GPL8673_F31C3_1P00036
GPL8673_F31C3_1P00406
GPL8673_F31C3_1P00495
GPL9450_F31C3.1
cea2.c.03243
Expression_cluster (146)
Interaction (101)
Map_infoMapIPosition29.7598
PositivePositive_cloneB0467Author_evidencePage AM
F31C3Inferred_automaticallyFrom sequence, transcript, pseudogene data
Y62C9Author_evidencePage AM
Pseudo_map_position
Reference (13)
Remark[Page AM] Is transpliced by SL-1. Isolated from mixed stage cDNA by using SL1, and known 3' seq from CEESH33F. Hybridises to YACs Y62C9, and by PCR and Southerns to cosmid B0467.
cDNAs CEMSA21F,CEMSA21R,CEMSH33F,CEMSH33R represent this gene. They have been taken out of the moleculat information above. [sdm 11/2000]
PPIase or cyclophilin, EC 5.2.1.8
This gene has been renamed with approval of the CGC (cyp-5->cyn-5)Person_evidenceWBPerson466
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene