WormBase Tree Display for Gene: WBGene00000490
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| WBGene00000490 | Evidence | CGC_data_submission | |||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | C27A7 | ||||||
| Identity | Version | 2 | |||||||
| Name | CGC_name | che-11 | Person_evidence | WBPerson261 | |||||
| Sequence_name | C27A7.4 | ||||||||
| Molecular_name | C27A7.4 | ||||||||
| C27A7.4.1 | |||||||||
| CE42072 | |||||||||
| Other_name | mev-4 | ||||||||
| ift-140 | |||||||||
| CELE_C27A7.4 | Accession_evidence | NDB | BX284605 | ||||||
| Public_name | che-11 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:21 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 11 Jun 2018 11:44:56 | WBPerson1983 | Name_change | Other_name | ift-140 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | che | ||||||||
| Reference_allele | WBVar00144321 | ||||||||
| Allele (91) | |||||||||
| Legacy_information | e1810 : no FITC uptake by amphids or phasmids; defective in osmotic avoidance and dauer formation. ES1 ME0. NA2(e1815). | ||||||||
| See also e1810, e1815 | |||||||||
| [C.elegansII] e1810 : Dyf (no FITC uptake by amphids or phasmids); defective in osmotic avoidance and dauer formation; irregular amphid cilia, abnormal staining, abnormal CEP cilia etc.. ES1 ME0. OA>6: e1815, m162, mn387, mn393. [Perkins et al. 1986; Starich et al. 1995; SP; DR] | |||||||||
| Strain | WBStrain00034362 | ||||||||
| WBStrain00034364 | |||||||||
| WBStrain00034366 | |||||||||
| WBStrain00040626 | |||||||||
| WBStrain00004476 | |||||||||
| WBStrain00006275 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (20) | |||||||||
| Ortholog (41) | |||||||||
| Paralog | WBGene00003883 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | che-11 encodes a large, unfamiliar protein with orthologs in vertebrates and arthropods (e.g., KIAA0590 and CG11838-PA) and in Chlamydomonas (IFT140), as well as distant similarity to OSM-1 and ZK520.1; che-11 is required for normal synthesis of sensory cilia (via intraflagellar transport) in sensory neurons, osmotic avoidance, and dauer formation. | Paper_evidence | WBPaper00004715 | |||||
| WBPaper00005244 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Involved in several processes, including dauer entry; determination of adult lifespan; and positive regulation of intracellular transport. Located in non-motile cilium. Expressed in head and neurons. Human ortholog(s) of this gene implicated in retinitis pigmentosa and short-rib thoracic dysplasia 9 with or without polydactyly. Is an ortholog of human IFT140 (intraflagellar transport 140). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0110097 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:29077) | ||||
| DOID:10584 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:29077) | ||||||
| Molecular_info | Corresponding_CDS | C27A7.4 | |||||||
| Corresponding_CDS_history | C27A7.4:wp87 | ||||||||
| C27A7.4:wp109 | |||||||||
| C27A7.4:wp152 | |||||||||
| C27A7.4:wp187 | |||||||||
| Corresponding_transcript | C27A7.4.1 | ||||||||
| Other_sequence (12) | |||||||||
| Associated_feature | WBsf653189 | ||||||||
| WBsf653190 | |||||||||
| WBsf669476 | |||||||||
| WBsf1001524 | |||||||||
| WBsf1001525 | |||||||||
| WBsf1020537 | |||||||||
| WBsf1020538 | |||||||||
| WBsf234628 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00041311 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00000647 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00029254 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00011237 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Chronogram1245 | ||||||||
| Expr4408 | |||||||||
| Expr5349 | |||||||||
| Expr10130 | |||||||||
| Expr1025654 | |||||||||
| Expr1030288 | |||||||||
| Expr1145353 | |||||||||
| Expr2009960 | |||||||||
| Expr2028200 | |||||||||
| Drives_construct | WBCnstr00003173 | ||||||||
| WBCnstr00006284 | |||||||||
| WBCnstr00011973 | |||||||||
| WBCnstr00021216 | |||||||||
| WBCnstr00037500 | |||||||||
| Construct_product | WBCnstr00006284 | ||||||||
| WBCnstr00008461 | |||||||||
| WBCnstr00015631 | |||||||||
| WBCnstr00015642 | |||||||||
| WBCnstr00015646 | |||||||||
| WBCnstr00015650 | |||||||||
| WBCnstr00015651 | |||||||||
| WBCnstr00017220 | |||||||||
| WBCnstr00021216 | |||||||||
| WBCnstr00037500 | |||||||||
| Microarray_results | SMD_C27A7.4 | ||||||||
| 173553_s_at | |||||||||
| A_12_P107076 | |||||||||
| Aff_C27A7.4 | |||||||||
| GPL13394_WBGene00000490 | |||||||||
| GPL13914_C27A7.4 | |||||||||
| GPL14144_C27A7.4_2861-2920_0.820_54_B | |||||||||
| GPL14144_C27A7.4_3866-3925_0.918_5_C | |||||||||
| GPL14144_C27A7.4_4123-4182_0.950_1_A | |||||||||
| GPL19516_CGZ0006199 | |||||||||
| GPL21109_C27A7.4 | |||||||||
| GPL3518_CE31887 | |||||||||
| GPL8304_CE_WBGene00000490_A | |||||||||
| GPL8673_C27A7_4P02920 | |||||||||
| GPL8673_C27A7_4P03127 | |||||||||
| GPL8673_C27A7_4P03444 | |||||||||
| GPL9450_C27A7.4 | |||||||||
| cea2.p.109808 | |||||||||
| Expression_cluster (189) | |||||||||
| Interaction (36) | |||||||||
| WBProcess | WBbiopr:00000012 | ||||||||
| Map_info | Map | V | Position | 3.67501 | Error | 0.005038 | |||
| Well_ordered | |||||||||
| Positive | Positive_clone | C27A7 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | 2_point | 790 | |||||||
| Multi_point | 722 | ||||||||
| 1172 | |||||||||
| 1807 | |||||||||
| 3067 | |||||||||
| 3068 | |||||||||
| 3069 | |||||||||
| 3070 | |||||||||
| 3071 | |||||||||
| 3072 | |||||||||
| 5065 | |||||||||
| Pos_neg_data | 8320 | ||||||||
| Reference (73) | |||||||||
| Remark | Sequence connection from [Qin H, Barr MM] | ||||||||
| Method | Gene |
