WormBase Tree Display for Gene: WBGene00006529

WBGene00006529 SMap: S_parent: Sequence: C47B2
  Identity: Version: 1
    Name: CGC_name: tba-2
      Sequence_name: C47B2.3
      Molecular_name: C47B2.3
        C47B2.3.1
        CE17563
        C47B2.3.2
      Other_name: Alpha-tubulin Accession_evidence: EMBL D14965
        TUBA4B
        mel-45 Person_evidence: WBPerson399
        CELE_C47B2.3 Accession_evidence: NDB BX284601
      Public_name: tba-2
    DB_info: Database (12)
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:40 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: tba
    Allele (42)
    Legacy_information: [C.elegansII] NMK. Encodes alpha tubulin. tba-2:lacZ expressed in touch cells, motor neurons and certain other neurons. [SQ]
      [Mains PE] Dominant, temperature-sensitive maternal-effect lethal. Defective early cleavage divisions. Homozygous nonconditional maternal-effect lethal.
    Strain: WBStrain00008449
      WBStrain00008455
      WBStrain00008457
      WBStrain00007877
    RNASeq_FPKM (74)
    GO_annotation (24)
    Contained_in_operon: CEOP1680
    Ortholog (50)
    Paralog (16)
    Structured_description: Concise_description: tba-2 encodes an alpha-tubulin. Paper_evidence: WBPaper00004402
            WBPaper00006395
          Curator_confirmed: WBPerson48
            WBPerson1843
          Date_last_updated: 08 Jan 2009 00:00:00
      Automated_description: Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Involved in several processes, including centrosome localization; establishment of mitotic spindle orientation; and regulation of cytokinesis. Predicted to be located in cytoplasm and microtubule. Expressed in several structures, including body wall musculature; intestine; neurons; pharynx; and ventral nerve cord. Human ortholog(s) of this gene implicated in thrombocytopenia. Is an ortholog of human TUBA8 (tubulin alpha 8) and TUBAL3 (tubulin alpha like 3). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:1588 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:12410)
  Molecular_info: Corresponding_CDS: C47B2.3
    Corresponding_CDS_history: C47B2.3b:wp123
    Corresponding_transcript: C47B2.3.1
      C47B2.3.2
    Other_sequence (137)
    Associated_feature (11)
  Experimental_info: RNAi_result (52)
    Expr_pattern (11)
    Drives_construct: WBCnstr00009169
      WBCnstr00012441
      WBCnstr00039275
    Construct_product: WBCnstr00004942
      WBCnstr00015886
      WBCnstr00038427
    Microarray_results (22)
    Expression_cluster (205)
    Interaction: WBInteraction000005363
      WBInteraction000005364
      WBInteraction000005365
      WBInteraction000005366
      WBInteraction000009415
      WBInteraction000009533
      WBInteraction000028479
      WBInteraction000032682
      WBInteraction000033542
      WBInteraction000034587
      WBInteraction000036446
      WBInteraction000036918
      WBInteraction000037906
      WBInteraction000038145
      WBInteraction000038977
      WBInteraction000039855
      WBInteraction000039858
      WBInteraction000039865
      WBInteraction000040875
      WBInteraction000042327
      WBInteraction000042328
      WBInteraction000042479
      WBInteraction000044301
      WBInteraction000044448
      WBInteraction000044804
      WBInteraction000046793
      WBInteraction000046798
      WBInteraction000046800
      WBInteraction000046802
      WBInteraction000046945
      WBInteraction000047221
      WBInteraction000047222
      WBInteraction000047393
      WBInteraction000047659
      WBInteraction000048112
      WBInteraction000048537
      WBInteraction000049448
      WBInteraction000050034
      WBInteraction000050190
      WBInteraction000100336
      WBInteraction000102550
      WBInteraction000102589
      WBInteraction000103011
      WBInteraction000103110
      WBInteraction000103467
      WBInteraction000103915
      WBInteraction000104077
      WBInteraction000104181
      WBInteraction000104258
      WBInteraction000104523
      WBInteraction000106229
      WBInteraction000112516
      WBInteraction000113406
      WBInteraction000114698
      WBInteraction000122151
      WBInteraction000124415
      WBInteraction000125514
      WBInteraction000134496
      WBInteraction000135225
      WBInteraction000137017
      WBInteraction000140199
      WBInteraction000145952
      WBInteraction000146160
      WBInteraction000146623
      WBInteraction000148021
      WBInteraction000148646
      WBInteraction000151196
      WBInteraction000151817
      WBInteraction000159942
      WBInteraction000162793
      WBInteraction000165272
      WBInteraction000168960
      WBInteraction000171421
      WBInteraction000171744
      WBInteraction000171884
      WBInteraction000177745
      WBInteraction000180169
      WBInteraction000181838
      WBInteraction000185502
      WBInteraction000191809
      WBInteraction000194936
      WBInteraction000195149
      WBInteraction000196304
      WBInteraction000205805
      WBInteraction000209116
      WBInteraction000210348
      WBInteraction000218895
      WBInteraction000219278
      WBInteraction000220104
      WBInteraction000221149
      WBInteraction000222374
      WBInteraction000223360
      WBInteraction000225030
      WBInteraction000225684
      WBInteraction000225934
      WBInteraction000226266
      WBInteraction000226955
      WBInteraction000234962
      WBInteraction000238179
      WBInteraction000238617
      WBInteraction000238725
      WBInteraction000243661
      WBInteraction000243755
      WBInteraction000243793
      WBInteraction000243794
      WBInteraction000243795
      WBInteraction000243796
      WBInteraction000243797
      WBInteraction000243798
      WBInteraction000243799
      WBInteraction000243800
      WBInteraction000243801
      WBInteraction000243802
      WBInteraction000243803
      WBInteraction000243804
      WBInteraction000243805
      WBInteraction000243806
      WBInteraction000243807
      WBInteraction000243808
      WBInteraction000243809
      WBInteraction000243810
      WBInteraction000243811
      WBInteraction000243812
      WBInteraction000243813
      WBInteraction000243814
      WBInteraction000243815
      WBInteraction000243816
      WBInteraction000243817
      WBInteraction000243818
      WBInteraction000243907
      WBInteraction000243990
      WBInteraction000244024
      WBInteraction000246016
      WBInteraction000246481
      WBInteraction000250081
      WBInteraction000250082
      WBInteraction000250083
      WBInteraction000250084
      WBInteraction000251208
      WBInteraction000252935
      WBInteraction000256199
      WBInteraction000260785
      WBInteraction000260985
      WBInteraction000262013
      WBInteraction000263513
      WBInteraction000264078
      WBInteraction000266986
      WBInteraction000266987
      WBInteraction000267468
      WBInteraction000271014
      WBInteraction000274678
      WBInteraction000275723
      WBInteraction000280559
      WBInteraction000281640
      WBInteraction000283919
      WBInteraction000285647
      WBInteraction000290157
      WBInteraction000293152
      WBInteraction000296869
      WBInteraction000297198
      WBInteraction000299583
      WBInteraction000302828
      WBInteraction000306361
      WBInteraction000306738
      WBInteraction000309062
      WBInteraction000311243
      WBInteraction000313117
      WBInteraction000316747
      WBInteraction000318641
      WBInteraction000322756
      WBInteraction000323555
      WBInteraction000324682
      WBInteraction000324693
      WBInteraction000325364
      WBInteraction000328427
      WBInteraction000333185
      WBInteraction000334721
      WBInteraction000338733
      WBInteraction000338936
      WBInteraction000340898
      WBInteraction000340899
      WBInteraction000340900
      WBInteraction000345493
      WBInteraction000350894
      WBInteraction000352155
      WBInteraction000355058
      WBInteraction000362555
      WBInteraction000363411
      WBInteraction000363412
      WBInteraction000363450
      WBInteraction000364049
      WBInteraction000370433
      WBInteraction000373595
      WBInteraction000374356
      WBInteraction000378056
      WBInteraction000378169
      WBInteraction000379119
      WBInteraction000379136
      WBInteraction000380643
      WBInteraction000382694
      WBInteraction000383285
      WBInteraction000383912
      WBInteraction000383923
      WBInteraction000389759
      WBInteraction000391023
      WBInteraction000392801
      WBInteraction000394093
      WBInteraction000395210
      WBInteraction000395828
      WBInteraction000397442
      WBInteraction000399181
      WBInteraction000406532
      WBInteraction000410328
      WBInteraction000411667
      WBInteraction000413394
      WBInteraction000415662
      WBInteraction000415680
      WBInteraction000417563
      WBInteraction000418884
      WBInteraction000419618
      WBInteraction000421662
      WBInteraction000425097
      WBInteraction000426329
      WBInteraction000426472
      WBInteraction000431679
      WBInteraction000432512
      WBInteraction000434028
      WBInteraction000434399
      WBInteraction000436954
      WBInteraction000438870
      WBInteraction000441906
      WBInteraction000443706
      WBInteraction000444327
      WBInteraction000445654
      WBInteraction000448576
      WBInteraction000450322
      WBInteraction000450674
      WBInteraction000453516
      WBInteraction000459405
      WBInteraction000461127
      WBInteraction000461266
      WBInteraction000463414
      WBInteraction000463439
      WBInteraction000465231
      WBInteraction000465696
      WBInteraction000466979
      WBInteraction000467639
      WBInteraction000467928
      WBInteraction000467931
      WBInteraction000468342
      WBInteraction000468919
      WBInteraction000469466
      WBInteraction000469706
      WBInteraction000471049
      WBInteraction000473055
      WBInteraction000501154
      WBInteraction000501155
      WBInteraction000501522
      WBInteraction000504721
      WBInteraction000517640
      WBInteraction000517731
      WBInteraction000523250
      WBInteraction000524387
      WBInteraction000540925
      WBInteraction000544735
      WBInteraction000549738
      WBInteraction000555373
      WBInteraction000558518
      WBInteraction000558885
      WBInteraction000561775
      WBInteraction000562701
      WBInteraction000564332
      WBInteraction000566030
      WBInteraction000566281
      WBInteraction000566560
      WBInteraction000567296
      WBInteraction000567345
      WBInteraction000569236
      WBInteraction000570615
      WBInteraction000571987
      WBInteraction000572692
      WBInteraction000572902
      WBInteraction000573597
      WBInteraction000576068
      WBInteraction000579587
      WBInteraction000580442
      WBInteraction000582573
      WBInteraction000585336
      WBInteraction000585953
  Map_info: Map: I Position: 16.7819 Error: 0.095464
    Positive: Positive_clone: C47B2 Inferred_automatically: From sequence, transcript, pseudogene data
        NW#A4B
    Mapping_data: Multi_point: 5586
        5686
  Reference (57)
  Remark: Sequence connection updated on advice of JAH (was previously connected to F26E4.8)
    Sequence connection from [Gremke L, Culotti JG]
  Method: Gene