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WormBase Tree Display for Gene: WBGene00004882

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Name Class

WBGene00004882SMapS_parentSequenceF46B6
IdentityVersion1
NameCGC_namesmg-4Person_evidenceWBPerson261
Sequence_nameF46B6.3
Molecular_nameF46B6.3a
F46B6.3a.1
CE26973
F46B6.3b
CE30440
F46B6.3b.1
Other_namemab-14
CELE_F46B6.3Accession_evidenceNDBBX284605
Public_namesmg-4
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:36WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classsmg
Reference_alleleWBVar00088765
Allele (31)
Legacy_informationSee also ma116
[C.elegansII] ma116 : adult male has swollen bursa, adult hermaphrodite has protruding vulva. ME1. Recessive suppressor of unc-54(r293),tra-2(e1209), etc.; suppression reduced bymaternal rescue. unc-54 nonsense RNAs accumulate. OA3: r1181, e2615psu, e2616psu. Cloned: YAC and phage rescue. [Hodgkin et al. 1989; Pulak and Anderson 1993; CB; TR]
StrainWBStrain00034951
WBStrain00004551
WBStrain00004567
WBStrain00051118
WBStrain00055592
WBStrain00055594
WBStrain00055593
RNASeq_FPKM (74)
GO_annotation (13)
Contained_in_operonCEOP5236
Ortholog (30)
Structured_descriptionAutomated_descriptionPredicted to enable mRNA binding activity. Involved in male genitalia development; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; and obsolete hermaphrodite genitalia development. Located in nucleus and perinuclear region of cytoplasm. Expressed in intestinal cell; muscle cell; and neurons. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability 14. Is an ortholog of human UPF3A (UPF3A regulator of nonsense mediated mRNA decay) and UPF3B (UPF3B regulator of nonsense mediated mRNA decay).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0060821Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:20439)
Molecular_infoCorresponding_CDSF46B6.3a
F46B6.3b
Corresponding_CDS_historyF46B6.3:wp46
F46B6.3:wp69
F46B6.3b:wp76
Corresponding_transcriptF46B6.3a.1
F46B6.3b.1
Other_sequenceCBC05396_1
Associated_featureWBsf234278
WBsf234279
Experimental_infoRNAi_resultWBRNAi00094500Inferred_automaticallyRNAi_primary
WBRNAi00008069Inferred_automaticallyRNAi_primary
WBRNAi00047495Inferred_automaticallyRNAi_primary
WBRNAi00085061Inferred_automaticallyRNAi_primary
WBRNAi00094403Inferred_automaticallyRNAi_primary
WBRNAi00015065Inferred_automaticallyRNAi_primary
WBRNAi00047493Inferred_automaticallyRNAi_primary
WBRNAi00094395Inferred_automaticallyRNAi_primary
Expr_patternExpr110
Expr1337
Expr1022685
Expr1032421
Expr1151332
Expr2015910
Expr2034143
Drives_constructWBCnstr00010227
WBCnstr00035343
Construct_productWBCnstr00035343
AntibodyWBAntibody00001272
Microarray_results (28)
Expression_cluster (112)
InteractionWBInteraction000000048
WBInteraction000001365
WBInteraction000001366
WBInteraction000003958
WBInteraction000029390
WBInteraction000029633
WBInteraction000030552
WBInteraction000037986
WBInteraction000039978
WBInteraction000114480
WBInteraction000126614
WBInteraction000126985
WBInteraction000127040
WBInteraction000147137
WBInteraction000147138
WBInteraction000151144
WBInteraction000151145
WBInteraction000157370
WBInteraction000158852
WBInteraction000158853
WBInteraction000158854
WBInteraction000158855
WBInteraction000158856
WBInteraction000158857
WBInteraction000159427
WBInteraction000162190
WBInteraction000162503
WBInteraction000162518
WBInteraction000166260
WBInteraction000166261
WBInteraction000166407
WBInteraction000226217
WBInteraction000226239
WBInteraction000324749
WBInteraction000361697
WBInteraction000413176
WBInteraction000517351
WBInteraction000517352
WBInteraction000517353
WBInteraction000517354
WBInteraction000518885
WBInteraction000518890
WBInteraction000536770
WBInteraction000536774
WBInteraction000542479
WBInteraction000555856
WBInteraction000555857
WBInteraction000556829
WBInteraction000575468
WBInteraction000582151
Map_infoMapVPosition2.19411Error0.006525
Well_ordered
PositiveInside_rearreDf1
Positive_cloneF46B6Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_data2_point3387
Multi_point1192
3101
3102
5376
Pos_neg_data4574
4575
Reference (38)
MethodGene