WormBase Tree Display for Gene: WBGene00016990
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WBGene00016990 | SMap | S_parent | Sequence | CD4 | |||
---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||
Name | CGC_name | vps-37 | Person_evidence | WBPerson3188 | |||
Sequence_name | CD4.4 | ||||||
Molecular_name | CD4.4 | ||||||
CD4.4.1 | |||||||
CE16952 | |||||||
Other_name | CELE_CD4.4 | Accession_evidence | NDB | BX284605 | |||
Public_name | vps-37 | ||||||
DB_info | Database | AceView | gene | 5G71 | |||
WormQTL | gene | WBGene00016990 | |||||
WormFlux | gene | WBGene00016990 | |||||
NDB | locus_tag | CELE_CD4.4 | |||||
Panther | gene | CAEEL|WormBase=WBGene00016990|UniProtKB=O44158 | |||||
family | PTHR13678 | ||||||
NCBI | gene | 178944 | |||||
RefSeq | protein | NM_072073.5 | |||||
TREEFAM | TREEFAM_ID | TF321840 | |||||
TrEMBL | UniProtAcc | O44158 | |||||
UniProt_GCRP | UniProtAcc | O44158 | |||||
Species | Caenorhabditis elegans | ||||||
History | Version_change (2) | ||||||
Status | Live | ||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | vps | ||||||
Allele (15) | |||||||
Strain | WBStrain00002948 | ||||||
WBStrain00036336 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation | 00032087 | ||||||
00032088 | |||||||
00032089 | |||||||
00032090 | |||||||
00032091 | |||||||
00032092 | |||||||
00032093 | |||||||
00032094 | |||||||
00032095 | |||||||
00032096 | |||||||
00032097 | |||||||
00032098 | |||||||
00032099 | |||||||
00032100 | |||||||
Contained_in_operon | CEOP5076 | ||||||
Ortholog (44) | |||||||
Structured_description | Concise_description | vps-37 encodes the C. elegans ortholog of Saccharomyces cerevisiae Srn2p/Vps37p, a member of the endosomal sorting ESCRT-I complex that functions in endosomal sorting of mono-ubiquitinated membrane proteins; in C. elegans, VPS-37 is an essential component of the ESCRT-I complex (other members include VPS-28, MVB-12, and TSG-101) that affects the rate at which cell surface receptors are degraded and hence, the rate at which their activity is downregulated; a VPS-37::GFP fusion protein localizes to the cytosol and to endosomal membranes. | Paper_evidence | WBPaper00031035 | |||
Curator_confirmed | WBPerson1843 | ||||||
Date_last_updated | 09 Jul 2010 00:00:00 | ||||||
Automated_description | Involved in receptor catabolic process. Located in cytosol and endosome membrane. Part of ESCRT I complex. Expressed in head and tail. Is an ortholog of human VPS37B (VPS37B subunit of ESCRT-I). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | CD4.4 | |||||
Corresponding_transcript | CD4.4.1 | ||||||
Other_sequence (14) | |||||||
Associated_feature | WBsf646815 | ||||||
WBsf231771 | |||||||
Experimental_info | RNAi_result (60) | ||||||
Expr_pattern | Expr5605 | ||||||
Expr1018249 | |||||||
Expr1037296 | |||||||
Expr1147284 | |||||||
Expr2018028 | |||||||
Expr2036165 | |||||||
Drives_construct | WBCnstr00003454 | ||||||
WBCnstr00027652 | |||||||
Construct_product | WBCnstr00000920 | ||||||
WBCnstr00027652 | |||||||
Microarray_results (20) | |||||||
Expression_cluster (105) | |||||||
Interaction (36) | |||||||
Map_info | Map | V | Position | -1.37551 | Error | 0.00596 | |
Positive | Positive_clone | CD4 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Pseudo_map_position | |||||||
Reference | WBPaper00027740 | ||||||
WBPaper00031035 | |||||||
WBPaper00031212 | |||||||
WBPaper00031867 | |||||||
WBPaper00038491 | |||||||
WBPaper00038585 | |||||||
WBPaper00039823 | |||||||
WBPaper00055090 | |||||||
WBPaper00064078 | |||||||
WBPaper00064325 | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |