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WormBase Tree Display for Gene: WBGene00006381

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Name Class

WBGene00006381SMapS_parentSequenceY54E2A
IdentityVersion1
NameCGC_nametac-1Person_evidenceWBPerson208
Sequence_nameY54E2A.3
Molecular_nameY54E2A.3
Y54E2A.3.1
CE20302
Other_name2P40Accession_evidenceEMBLAF326937
CELE_Y54E2A.3Accession_evidenceNDBBX284602
Public_nametac-1
DB_infoDatabaseAceViewgene2P38
WormQTLgeneWBGene00006381
WormFluxgeneWBGene00006381
NDBlocus_tagCELE_Y54E2A.3
NCBIgene175133
RefSeqproteinNM_064658.8
SwissProtUniProtAccG5ECG0
UniProt_GCRPUniProtAccG5ECG0
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:40WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classtac
Allele (20)
StrainWBStrain00037424
WBStrain00007335
WBStrain00007333
WBStrain00050672
RNASeq_FPKM (74)
GO_annotation00011665
00011666
00011667
00011668
00011669
00011670
00011671
00011672
00011673
00011674
00011675
00011676
00011677
00011678
00011679
00011680
00011681
00011682
00011683
00011684
00011685
00011686
00011687
00011688
00011689
00011690
00011691
00011692
00011693
00011694
00011695
00011696
00011697
00011698
00011699
00011700
00011701
00011702
00011703
00011704
00011705
00011706
00011707
00011708
00011709
00011710
Contained_in_operonCEOP2648
Ortholog (20)
Structured_descriptionConcise_descriptiontac-1 encodes the sole C. elegans member of the transforming acidic coiled-coil (TACC) protein family whose members contain highly conserved C-terminal coiled-coil domains; during early embryogenesis, TAC-1 activity is essential for such microtubule-based processes as pronuclear migration and mitotic spindle elongation; TAC-1 interacts in vivo with, and mutually stabilizes, ZYG-9, a microtubule-associated protein (MAP) also required for pronuclear migration; TAC-1 also interacts with ZYG-8, a kinase domain-containing MAP required for proper spindle positioning during anaphase of the first embryonic cell division; TAC-1 is a core component of centrosomes, and also localizes to the meiotic spindle poles, the mitotic spindle, and the cytoplasm.Paper_evidenceWBPaper00006059
WBPaper00006060
WBPaper00006061
Curator_confirmedWBPerson1843
Date_last_updated17 Mar 2006 00:00:00
Automated_descriptionEnables protein domain specific binding activity. Involved in several processes, including regulation of microtubule polymerization or depolymerization; sexual reproduction; and spindle organization. Located in cytoplasm; kinetochore; and microtubule cytoskeleton.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSY54E2A.3
Corresponding_transcriptY54E2A.3.1
Other_sequenceAF326937
FG620567.1
Associated_featureWBsf650765
WBsf224306
Experimental_infoRNAi_result (18)
Expr_patternExpr2681
Expr2683
Expr2684
Expr2685
Expr12439
Expr1020108
Expr1032578
Expr1160809
Expr2017202
Expr2035338
Construct_productWBCnstr00005024
WBCnstr00010900
WBCnstr00015616
WBCnstr00015617
WBCnstr00020876
WBCnstr00021102
WBCnstr00022253
WBCnstr00022255
WBCnstr00022258
WBCnstr00040176
Antibody (6)
Microarray_results (18)
Expression_cluster (114)
Interaction (152)
Map_infoMapIIPosition23.4578Error0.010609
PositivePositive_cloneY54E2AInferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
Reference (35)
RemarkSequence connection from [Bellanger J-M, Gonczy P], 02/06/10 krb
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene