WormBase Tree Display for Gene: WBGene00001535
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WBGene00001535 | SMap | S_parent | Sequence | C49H3 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name | CGC_name | gcy-8 | Person_evidence | WBPerson655 | |||||
Sequence_name | C49H3.1 | ||||||||
Molecular_name | C49H3.1 | ||||||||
C49H3.1.1 | |||||||||
CE42080 | |||||||||
Other_name | CELE_C49H3.1 | Accession_evidence | NDB | BX284604 | |||||
Public_name | gcy-8 | ||||||||
DB_info | Database (12) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:24 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | gcy | ||||||||
Allele (54) | |||||||||
Legacy_information | [Yu S] gcy for Guanylyl CYclase. No mutations known. gcy-8::GFP expressed only in AFD. Predicted gene C49H3.2 | ||||||||
Strain | WBStrain00031124 | ||||||||
WBStrain00031127 | |||||||||
WBStrain00031134 | |||||||||
WBStrain00022003 | |||||||||
WBStrain00022015 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation | 00092868 | ||||||||
00092869 | |||||||||
00092870 | |||||||||
00092871 | |||||||||
00092872 | |||||||||
00092873 | |||||||||
00092874 | |||||||||
00092875 | |||||||||
00092876 | |||||||||
00092877 | |||||||||
00092878 | |||||||||
00092879 | |||||||||
00092880 | |||||||||
00092881 | |||||||||
00092882 | |||||||||
00092883 | |||||||||
00092884 | |||||||||
00092885 | |||||||||
00092886 | |||||||||
00092887 | |||||||||
00092888 | |||||||||
00092889 | |||||||||
00092890 | |||||||||
00092891 | |||||||||
00092892 | |||||||||
00092893 | |||||||||
00092894 | |||||||||
00092895 | |||||||||
00092896 | |||||||||
00092897 | |||||||||
00092898 | |||||||||
00092899 | |||||||||
00092900 | |||||||||
00092901 | |||||||||
00108906 | |||||||||
00108907 | |||||||||
00108908 | |||||||||
00108909 | |||||||||
Ortholog (35) | |||||||||
Paralog (37) | |||||||||
Structured_description | Concise_description | gcy-8 encodes a receptor-type guanylyl cyclase that, along with gcy-18 and gcy-23, constitutes a subfamily of guanylyl cyclase genes in C. elegans; gcy-8 functions redundantly with gcy-18 and gcy-23, and upstream of tax-4, to regulate thermotaxis via the AFD thermosensory neurons, although of the three guanylyl cyclases required, genetic analyses suggest that GCY-18 is the primary guanylyl cyclase required; GCY-8 is expressed exclusively in the AFD thermosensory neurons where it localizes to sensory endings; GCY-8 expression in the AFD neurons requires activity of the TAX-2/4 cyclic nucleotide gated channel and the CMK-1 Ca2+/calmodulin-dependent protein kinase I, while maintenance of GCY-8 expression requires the OTD/OTX homeodomain protein TTX-1. | Paper_evidence | WBPaper00002839 | |||||
WBPaper00004879 | |||||||||
WBPaper00006343 | |||||||||
WBPaper00027040 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 07 Aug 2006 00:00:00 | ||||||||
Automated_description | Enables guanylate cyclase activity. Involved in microvillus organization and response to temperature stimulus. Located in microvillus membrane and neuron projection terminus. Expressed in AFDL and AFDR. | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed (2) | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | C49H3.1 | |||||||
Corresponding_CDS_history | C49H3.1:wp187 | ||||||||
Corresponding_transcript | C49H3.1.1 | ||||||||
Other_sequence (14) | |||||||||
Associated_feature | WBsf646129 | ||||||||
WBsf980902 | |||||||||
WBsf980903 | |||||||||
WBsf228598 | |||||||||
Experimental_info | RNAi_result | WBRNAi00042833 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00012164 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00103221 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00012161 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00029995 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00042832 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern (12) | |||||||||
Drives_construct (41) | |||||||||
Construct_product | WBCnstr00011696 | ||||||||
WBCnstr00018503 | |||||||||
WBCnstr00036879 | |||||||||
Microarray_results (21) | |||||||||
Expression_cluster (102) | |||||||||
Interaction (30) | |||||||||
Map_info | Map | IV | Position | 3.50015 | Error | 0.000609 | |||
Positive | Positive_clone | C49H3 | Person_evidence | WBPerson4049 | |||||
Inferred_automatically | From sequence, transcript, pseudogene data | ||||||||
Mapping_data | Multi_point | 4941 | |||||||
Pseudo_map_position | |||||||||
Reference (72) | |||||||||
Remark | Data extracted from Yu et al. (1997) | ||||||||
C49H3.2 is dead merged into .1 [sdm 11.2000] | |||||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
Method | Gene |