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WormBase Tree Display for Gene: WBGene00000798

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Name Class

WBGene00000798EvidencePaper_evidenceWBPaper00005857
SMapS_parentSequenceC14A4
IdentityVersion2
NameCGC_namecrn-5Person_evidenceWBPerson1606
Sequence_nameC14A4.5
Molecular_nameC14A4.5
C14A4.5.1
CE02146
Other_nameexos-5Person_evidenceWBPerson699
WBPerson6229
CELE_C14A4.5Accession_evidenceNDBBX284602
Public_namecrn-5
DB_infoDatabaseAceViewgene2K883
WormQTLgeneWBGene00000798
WormFluxgeneWBGene00000798
NDBlocus_tagCELE_C14A4.5
PanthergeneCAEEL|WormBase=WBGene00000798|UniProtKB=G5EG59
familyPTHR11953
NCBIgene174634
RefSeqproteinNM_063883.4
SwissProtUniProtAccG5EG59
TREEFAMTREEFAM_IDTF315920
UniProt_GCRPUniProtAccG5EG59
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:21WBPerson1971EventImportedInitial conversion from geneace
204 Jun 2007 15:54:19WBPerson2970Name_changeOther_nameexos-5
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcrn
Allele (16)
RNASeq_FPKM (74)
GO_annotation00018523
00018524
00018525
00018526
00018527
00018528
00018529
00018530
00018531
00018532
00018533
00018534
00018535
00018536
00018537
00018538
00018539
00018540
00018541
00018542
00018543
00018544
00018545
00018546
Contained_in_operonCEOP2496
Ortholog (34)
ParalogWBGene00000202Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00007201Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptioncrn-5 encodes a cell death-related nuclease which is a homolog of Rrp46, an eukaryotic ribonulease component of the exosome, involved in RNA processing; crn-5 is believed to function in a large multinuclease complex, the degradeosome, whose components include the protein products of cps-6, crn-1, crn-4, cpy-13 and other non-nuclease components like wah-1, to promote apoptotic DNA degradation; crn-5 has been shown to bind DNA without detectable DNase activity but enhances the DNase activity of CRN-4, a DEDD family apoptotic DNAase and RNase.Paper_evidenceWBPaper00005857
WBPaper00036712
Curator_confirmedWBPerson324
Date_last_updated22 Oct 2010 00:00:00
Automated_descriptionEnables double-stranded DNA binding activity and enzyme binding activity. Involved in RNA processing and apoptotic DNA fragmentation. Part of exosome (RNase complex). Is an ortholog of human EXOSC5 (exosome component 5).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS292 version of WormBase
Date_last_updated24 Apr 2024 00:00:00
Molecular_infoCorresponding_CDSC14A4.5
Corresponding_transcriptC14A4.5.1
Other_sequenceHbac_isotig03698
CJC05327_1
CGC00890_1
CBC01241_1
EX010442.1
Associated_featureWBsf989405
WBsf222035
Experimental_infoRNAi_result (9)
Expr_patternExpr1018453
Expr1030497
Expr1144540
Expr2010540
Expr2028780
Drives_constructWBCnstr00037268
Construct_productWBCnstr00037268
Microarray_results (22)
Expression_cluster (86)
Interaction (40)
WBProcessWBbiopr:00000014
WBbiopr:00000103
Map_infoMapIIPosition3.12021Error0.000298
PositivePositive_cloneC14A4Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
Reference (9)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene