WormBase Tree Display for Gene: WBGene00003926

WBGene00003926 Evidence: CGC_data_submission
  SMap: S_parent: Sequence: F25H2
  Identity: Version: 2
    Name: CGC_name: pas-5 Person_evidence: WBPerson1551
      Sequence_name: F25H2.9
      Molecular_name: F25H2.9
        F25H2.9.1
        CE09654
      Other_name: syt-2 Paper_evidence: WBPaper00032104
        CELE_F25H2.9 Accession_evidence: NDB BX284601
      Public_name: pas-5
    DB_info: Database: AceView gene 1L143
        WormQTL gene WBGene00003926
        WormFlux gene WBGene00003926
        NDB locus_tag CELE_F25H2.9
        Panther gene CAEEL|WormBase=WBGene00003926|UniProtKB=Q95008
          family PTHR11599
        NCBI gene 172942
        RefSeq protein NM_060364.7
        SwissProt UniProtAcc Q95008
        TREEFAM TREEFAM_ID TF106211
        UniProt_GCRP UniProtAcc Q95008
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:33 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 09 Jan 2009 11:41:23 WBPerson2970 Name_change: Other_name: syt-2
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: pas
    Allele (12)
    Strain: WBStrain00036234
    RNASeq_FPKM (74)
    GO_annotation: 00087853
      00087854
      00087855
      00087856
      00087857
      00087858
      00087859
      00087860
      00087861
      00087862
      00087863
      00112010
      00112011
      00112012
      00112013
    Ortholog (37)
    Paralog (13)
    Structured_description: Concise_description: pas-5 encodes a proteasome alpha-type five subunit of the core 20S proteasome subcomplex; loss of pas-5 activity via RNAi results in a variety of defects including embryonic and larval lethality, sterility, and abnormal locomotion; loss of pas-5 activity also results in activation of SKN-1, a transcription factor required in adult worms for the acute response to oxidative stress and maternally for embryonic development. Paper_evidence: WBPaper00004402
            WBPaper00006395
            WBPaper00024497
            WBPaper00025054
            WBPaper00030965
          Curator_confirmed: WBPerson1843
          Date_last_updated: 18 Jan 2008 00:00:00
      Automated_description: Predicted to be involved in proteasomal protein catabolic process. Predicted to be located in nucleus. Predicted to be part of proteasome core complex, alpha-subunit complex. Expressed in body wall musculature; germ line; gonad; hypodermis; and vulva. Is an ortholog of human PSMA5 (proteasome 20S subunit alpha 5). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F25H2.9
    Corresponding_transcript: F25H2.9.1
    Other_sequence (108)
    Associated_feature: WBsf643695
      WBsf643696
      WBsf654826
      WBsf656880
      WBsf985038
      WBsf1010569
      WBsf218452
  Experimental_info: RNAi_result: WBRNAi00089497 Inferred_automatically: RNAi_primary
      WBRNAi00076338 Inferred_automatically: RNAi_primary
      WBRNAi00031395 Inferred_automatically: RNAi_primary
      WBRNAi00089422 Inferred_automatically: RNAi_primary
      WBRNAi00114679 Inferred_automatically: RNAi_primary
      WBRNAi00089450 Inferred_automatically: RNAi_primary
      WBRNAi00092755 Inferred_automatically: RNAi_primary
      WBRNAi00085344 Inferred_automatically: RNAi_primary
      WBRNAi00025228 Inferred_automatically: RNAi_primary
      WBRNAi00089431 Inferred_automatically: RNAi_primary
      WBRNAi00089438 Inferred_automatically: RNAi_primary
      WBRNAi00089442 Inferred_automatically: RNAi_primary
      WBRNAi00114680 Inferred_automatically: RNAi_primary
      WBRNAi00112133 Inferred_automatically: RNAi_primary
      WBRNAi00089440 Inferred_automatically: RNAi_primary
      WBRNAi00110835 Inferred_automatically: RNAi_primary
      WBRNAi00081285 Inferred_automatically: RNAi_primary
      WBRNAi00089451 Inferred_automatically: RNAi_primary
      WBRNAi00070176 Inferred_automatically: RNAi_primary
      WBRNAi00089446 Inferred_automatically: RNAi_primary
      WBRNAi00114681 Inferred_automatically: RNAi_primary
      WBRNAi00114678 Inferred_automatically: RNAi_primary
      WBRNAi00095584 Inferred_automatically: RNAi_primary
      WBRNAi00078788 Inferred_automatically: RNAi_primary
      WBRNAi00089444 Inferred_automatically: RNAi_primary
      WBRNAi00090973 Inferred_automatically: RNAi_primary
      WBRNAi00045545 Inferred_automatically: RNAi_primary
      WBRNAi00113773 Inferred_automatically: RNAi_primary
      WBRNAi00025229 Inferred_automatically: RNAi_primary
      WBRNAi00117144 Inferred_automatically: RNAi_primary
      WBRNAi00089435 Inferred_automatically: RNAi_primary
      WBRNAi00000032 Inferred_automatically: RNAi_primary
      WBRNAi00089427 Inferred_automatically: RNAi_primary
      WBRNAi00078722 Inferred_automatically: RNAi_primary
      WBRNAi00089498 Inferred_automatically: RNAi_primary
      WBRNAi00078757 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr9677
      Expr1027785
      Expr1031859
      Expr1149459
      Expr2014744
      Expr2032978
    Drives_construct: WBCnstr00008738
      WBCnstr00014220
      WBCnstr00035792
    Construct_product: WBCnstr00035792
    Microarray_results (22)
    Expression_cluster (164)
    Interaction (154)
  Map_info: Map: I Position: 5.05517 Error: 0.00012
    Positive: Positive_clone: F25H2 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (16)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene