WormBase Tree Display for Gene: WBGene00004737
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WBGene00004737 | Evidence | CGC_data_submission | |||||||
---|---|---|---|---|---|---|---|---|---|
SMap | S_parent | Sequence | F10G7 | ||||||
Identity | Version | 1 | |||||||
Name | CGC_name | scc-1 | Person_evidence | WBPerson421 | |||||
Sequence_name | F10G7.4 | ||||||||
Molecular_name | F10G7.4 | ||||||||
F10G7.4.1 | |||||||||
CE02628 | |||||||||
Other_name | coh-2 | Person_evidence | WBPerson421 | ||||||
WBPerson1819 | |||||||||
rad-21.1 | |||||||||
CELE_F10G7.4 | Accession_evidence | NDB | BX284602 | ||||||
Public_name | scc-1 | ||||||||
DB_info | Database (11) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:36 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | scc | ||||||||
Allele (26) | |||||||||
Legacy_information | [J. Loidl] RNAi phenotypes : ~98% embryo lethality, HIM (~3% males); protein localizes to somatic nuclei of the embryo and to nuclei at meiotic prophase | ||||||||
[J. Loidl] (F10G7.4) is homolog to the Rad21/Scc1/Rec8 family of cohesion proteins with knownmembers in S. cerevisiae, S. pombe, A. thaliana and vertebrates. R-S-R is the acronym of the founder family. | |||||||||
Strain | WBStrain00035987 | ||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation | 00064359 | ||||||||
00064360 | |||||||||
00064361 | |||||||||
00064362 | |||||||||
00064363 | |||||||||
00064364 | |||||||||
00064365 | |||||||||
00064366 | |||||||||
00064367 | |||||||||
00064368 | |||||||||
00064369 | |||||||||
00064370 | |||||||||
00064371 | |||||||||
00064372 | |||||||||
00064373 | |||||||||
00064374 | |||||||||
00064375 | |||||||||
00064376 | |||||||||
00113111 | |||||||||
00113112 | |||||||||
Ortholog (44) | |||||||||
Paralog | WBGene00000591 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
WormBase-Compara | |||||||||
Structured_description | Concise_description | scc-1 encodes a member of the Rad21/Rec8-like family of cohesion proteins that affects embryonic viability, fertility, the rate of embryonic cell divisions and the incidence of male progeny; interacts with ATL-1, F56D12.5, and F11E6.1 based on yeast two-hybrid assays, and is expressed in nondividing embryonic and germline nuclei. | Paper_evidence | WBPaper00004651 | |||||
WBPaper00004722 | |||||||||
WBPaper00005039 | |||||||||
WBPaper00018377 | |||||||||
Curator_confirmed | WBPerson48 | ||||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
Automated_description | Predicted to enable chromatin binding activity and damaged DNA binding activity. Involved in meiotic cell cycle. Located in nucleus. Part of cohesin complex. Expressed in several structures, including SDQ; germ line; seam cell; touch receptor neurons; and ventral nerve cord. Human ortholog(s) of this gene implicated in Cornelia de Lange syndrome 4; carcinoma (multiple); and endometrial cancer. Is an ortholog of human RAD21 (RAD21 cohesin complex component) and RAD21L1 (RAD21 cohesin complex component like 1). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:0080508 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9811) | ||||
DOID:0050866 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9811) | ||||||
DOID:3908 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9811) | ||||||
DOID:0080199 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9811) | ||||||
DOID:684 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9811) | ||||||
DOID:1380 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:9811) | ||||||
Molecular_info | Corresponding_CDS | F10G7.4 | |||||||
Corresponding_transcript | F10G7.4.1 | ||||||||
Other_sequence | CRC06495_1 | ||||||||
MP00107 | |||||||||
BXC03089_1 | |||||||||
CBC02363_1 | |||||||||
MI06164 | |||||||||
CJC04977_1 | |||||||||
CR03754 | |||||||||
RSC00091_1 | |||||||||
CJC01832_1 | |||||||||
MIC05797_1 | |||||||||
Associated_feature | WBsf644122 | ||||||||
WBsf987674 | |||||||||
WBsf221156 | |||||||||
Experimental_info | RNAi_result (17) | ||||||||
Expr_pattern | Expr1350 | ||||||||
Expr2579 | |||||||||
Expr11962 | |||||||||
Expr1015315 | |||||||||
Expr1032337 | |||||||||
Expr1148255 | |||||||||
Expr2015621 | |||||||||
Expr2033856 | |||||||||
Drives_construct | WBCnstr00035420 | ||||||||
Construct_product | WBCnstr00035420 | ||||||||
Antibody | WBAntibody00000375 | ||||||||
WBAntibody00000636 | |||||||||
WBAntibody00000645 | |||||||||
WBAntibody00000646 | |||||||||
Microarray_results | SMD_F10G7.4 | ||||||||
193295_at | |||||||||
A_12_P102518 | |||||||||
Aff_F10G7.4 | |||||||||
GPL13394_WBGene00004737 | |||||||||
GPL13914_F10G7.4 | |||||||||
GPL14144_F10G7.4_1591-1650_0.934_14_C | |||||||||
GPL14144_F10G7.4_1689-1748_0.941_12_B | |||||||||
GPL14144_F10G7.4_1817-1876_0.962_2_A | |||||||||
GPL19516_CGZ0015426 | |||||||||
GPL21109_F10G7.4 | |||||||||
GPL3518_CE02628 | |||||||||
GPL8304_CE_WBGene00004737_A | |||||||||
GPL8304_CE_WBGene00004737_B | |||||||||
GPL8673_F10G7_4P00548 | |||||||||
GPL8673_F10G7_4P00898 | |||||||||
GPL8673_F10G7_4P01657 | |||||||||
GPL9450_F10G7.4 | |||||||||
cea2.p.36002 | |||||||||
Expression_cluster (151) | |||||||||
Interaction (107) | |||||||||
WBProcess | WBbiopr:00000099 | ||||||||
Map_info | Map | II | Position | -3.59162 | Error | 0.111344 | |||
Positive | Positive_clone | F10G7 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Mapping_data | Multi_point | 4996 | |||||||
Pseudo_map_position | |||||||||
Reference (13) | |||||||||
Remark | Sequence connection from [Sugimoto A] | ||||||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
Method | Gene |