WormBase Tree Display for Gene: WBGene00000100

WBGene00000100 SMap: S_parent: Sequence: CHROMOSOME_X
  Identity: Version: 3
    Name: CGC_name: ajm-1 Person_evidence: WBPerson240
      Sequence_name: C25A11.4
      Molecular_name (42)
      Other_name: jam-1
        H08J11.c Curator_confirmed: WBPerson1983
          Remark: Old cosmid naming mapped via unique overlapping PCR_product on CDSs
        H08J11.a
        H08J11.b
        CELE_C25A11.4 Accession_evidence: NDB BX284606
      Public_name: ajm-1
    DB_info: Database: AceView gene XJ731
        WormQTL gene WBGene00000100
        WormFlux gene WBGene00000100
        NDB locus_tag CELE_C25A11.4
        Panther gene CAEEL|WormBase=WBGene00000100|UniProtKB=A0A1C3NSL9
          family PTHR21517
        NCBI gene 181148
        RefSeq protein (13)
        SwissProt UniProtAcc A0A1C3NSL9
        TrEMBL UniProtAcc H2KYC5
            Q95ZY7
        UniProt_GCRP UniProtAcc A0A1C3NSL9
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:20 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 01 Jul 2016 14:56:15 WBPerson1983 Event: Acquires_merge: WBGene00044785
        3 01 Jul 2016 14:56:15 WBPerson1983 Event: Acquires_merge: WBGene00019173
      Acquires_merge: WBGene00044785
        WBGene00019173
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: ajm
    Allele (507)
    Legacy_information: [Raich WB, Hardin JD] No mutants known. Encodes protein recognized by monoclonal antibody MH27, associated with apical cell-cell junctions. Predicted gene C25A11.4 + C25A11.3
    Strain (22)
    RNASeq_FPKM (74)
    GO_annotation: 00002423
      00002424
      00002425
      00002426
      00002427
      00002428
      00002429
      00002430
      00002431
      00002432
      00002433
      00002434
      00002435
      00002436
      00002437
      00002438
      00002439
      00002440
      00002441
      00002442
      00002443
      00090350
      00090351
      00106784
    Ortholog (27)
    Structured_description: Concise_description: ajm-1 encodes a member of the apical junction molecule class that is required for correct elongation of the C. elegans embryo; AJM-1 contains a coiled-coil motif; AJM-1 binds DLG-1 in vitro, in yeast two-hybrid assays, and in vivo; AJM-1 is mislocalized in a dlg-1(RNAi) background; LET-413 is required for rapid confinement of DLG-1 and AJM-1 to a narrow apical region in C. elegans epithelia; CLC-1 colocalizes with AJM-1; vab-9 mutations enhance the adhesion defects of ajm-1 mutants; ajm-1 is expressed at the apical borders of all epithelia. Paper_evidence: WBPaper00004765
            WBPaper00004961
            WBPaper00005194
            WBPaper00005946
            WBPaper00005969
          Curator_confirmed: WBPerson48
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable cytoskeletal protein binding activity. Involved in cell-cell junction organization and embryo development. Located in apicolateral plasma membrane; cell-cell junction; and plasma membrane bounded cell projection. Expressed in several structures, including arcade cell and epithelial cell. Is an ortholog of human AJM1 (apical junction component 1 homolog). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS (13)
    Corresponding_CDS_history: C25A11.4b:wp254
      C25A11.4c:wp254
      C25A11.4d:wp254
      C25A11.4e:wp254
    Corresponding_transcript (16)
    Other_sequence (84)
    Associated_feature (76)
  Experimental_info: RNAi_result (26)
    Expr_pattern (20)
    Drives_construct (23)
    Construct_product (11)
    Antibody: WBAntibody00000055
      WBAntibody00001322
    Microarray_results (94)
    Expression_cluster (304)
    Interaction: WBInteraction000003439
      WBInteraction000009532
      WBInteraction000009797
      WBInteraction000048696
      WBInteraction000126063
      WBInteraction000126365
      WBInteraction000126540
      WBInteraction000126541
      WBInteraction000126934
      WBInteraction000127258
      WBInteraction000143158
      WBInteraction000143159
      WBInteraction000146136
      WBInteraction000151150
      WBInteraction000151161
      WBInteraction000165151
      WBInteraction000165157
      WBInteraction000165471
      WBInteraction000171766
      WBInteraction000177204
      WBInteraction000190786
      WBInteraction000196873
      WBInteraction000231774
      WBInteraction000238802
      WBInteraction000239087
      WBInteraction000300928
      WBInteraction000302568
      WBInteraction000303785
      WBInteraction000304417
      WBInteraction000320245
      WBInteraction000320514
      WBInteraction000338585
      WBInteraction000357508
      WBInteraction000365172
      WBInteraction000394538
      WBInteraction000394647
      WBInteraction000396236
      WBInteraction000431798
      WBInteraction000450910
      WBInteraction000501503
      WBInteraction000501694
      WBInteraction000501695
      WBInteraction000502312
      WBInteraction000503351
      WBInteraction000503586
      WBInteraction000503851
      WBInteraction000504321
      WBInteraction000517240
      WBInteraction000517942
      WBInteraction000517943
      WBInteraction000517944
      WBInteraction000517945
      WBInteraction000517946
      WBInteraction000523968
      WBInteraction000539332
      WBInteraction000541403
      WBInteraction000541695
      WBInteraction000541696
      WBInteraction000541697
      WBInteraction000541698
      WBInteraction000541877
      WBInteraction000543637
      WBInteraction000543638
      WBInteraction000543639
      WBInteraction000543640
      WBInteraction000543641
      WBInteraction000543642
      WBInteraction000543643
      WBInteraction000543644
      WBInteraction000543645
      WBInteraction000543646
      WBInteraction000546473
      WBInteraction000546691
      WBInteraction000546724
      WBInteraction000546786
      WBInteraction000546803
      WBInteraction000552881
      WBInteraction000556075
      WBInteraction000556412
      WBInteraction000556936
      WBInteraction000557044
      WBInteraction000557051
      WBInteraction000557052
      WBInteraction000557055
      WBInteraction000557056
      WBInteraction000557080
      WBInteraction000557081
      WBInteraction000557083
      WBInteraction000557084
      WBInteraction000557093
      WBInteraction000558780
      WBInteraction000560330
      WBInteraction000561804
      WBInteraction000563629
      WBInteraction000565320
      WBInteraction000567612
      WBInteraction000569720
      WBInteraction000572707
      WBInteraction000578469
      WBInteraction000578877
      WBInteraction000582173
      WBInteraction000583793
      WBInteraction000584153
      WBInteraction000586370
  Map_info: Map: X Position: 0.672056 Error: 0.047992
    Positive: Positive_clone: C25A11 Person_evidence: WBPerson506
          Author_evidence: Hardin JD
          Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4150
    Pseudo_map_position
  Reference (133)
  Remark (3)
  Method: Gene