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WormBase Tree Display for Gene: WBGene00022793

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Name Class

WBGene00022793SMapS_parentSequenceZK686
IdentityVersion1
NameSequence_nameZK686.3
Molecular_nameZK686.3
ZK686.3.1
CE00457
Other_nameCELE_ZK686.3Accession_evidenceNDBBX284603
Public_nameZK686.3
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:06WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
StatusLive
Gene_infoBiotypeSO:0001217
Allele (24)
RNASeq_FPKM (74)
GO_annotation00043879
00043880
00043881
00043882
00043883
Contained_in_operonCEOP3452
Ortholog (43)
Structured_descriptionConcise_descriptionZK686.3 is orthologous to the putative tumor suppressor candidate 3 (TUSC3); TUSC3 is involved in plasma membrane magnesium ion transport; ZK686.3 is also orthologous to the S. cerevisiae dolichyl-diphosphooligosaccharide-protein glycotransferase gamma chain (34-kD) subunit, OST3.Paper_evidenceWBPaper00013569
WBPaper00013570
Curator_confirmedWBPerson324
WBPerson1823
WBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to be involved in protein N-linked glycosylation via asparagine. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of oligosaccharyltransferase complex. Used to study bacterial infectious disease. Human ortholog(s) of this gene implicated in X-linked immunodeficiency with magnesium defect, Epstein-Barr virus infection, and neoplasia; autosomal recessive intellectual developmental disorder 7; and congenital disorder of glycosylation Icc. Is an ortholog of human MAGT1 (magnesium transporter 1) and TUSC3 (tumor suppressor candidate 3).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoExperimental_modelDOID:104Homo sapiensPaper_evidenceWBPaper00059373
Curator_confirmedWBPerson324
Date_last_updated09 Mar 2023 00:00:00
Potential_modelDOID:0081183Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:30242)
DOID:0080319Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:28880)
DOID:0111839Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:28880)
Models_disease_in_annotationWBDOannot00000065
Molecular_infoCorresponding_CDSZK686.3
Corresponding_transcriptZK686.3.1
Other_sequence (72)
Associated_featureWBsf667103
WBsf667104
WBsf667105
WBsf227023
Experimental_infoRNAi_result (26)
Expr_patternExpr1010721
Expr1040083
Expr1163077
Expr2008936
Expr2027172
Drives_constructWBCnstr00023970
Construct_productWBCnstr00023970
Microarray_results (21)
Expression_clusterWBPaper00031040:TGF-beta_adult_downregulated
WBPaper00032528:L3_enriched
WBPaper00033065:cyc-1(RNAi)_downregulated
WBPaper00037950:BAG-neuron_blastula-embryo_expressed
WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
WBPaper00037950:germline-precursors_blastula-embryo_expressed
WBPaper00037950:intestine_L1-larva_expressed
WBPaper00037950:intestine_L2-larva_expressed
WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
WBPaper00038289:oocyte_protein
WBPaper00044426:rotenone_24h_upregulated
WBPaper00044501:gld-1_let-7_regulated
WBPaper00044736:flat_dev_expression
WBPaper00045316:prg-1_upregulated_L1
WBPaper00045316:prg-1_upregulated_L2
WBPaper00045316:prg-1_upregulated_L3
WBPaper00045521:Gender_Neutral
WBPaper00045774:clk-1_downregulated
WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
WBPaper00048657:plep-1(ttTi53821)_regulated
WBPaper00048910:mRNA-interacting_protein
WBPaper00048988:neuron_expressed
WBPaper00050015:ifg-1(RNAi)_downregulated
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
WBPaper00050726:OsmoticStress_regulated_Food
WBPaper00050726:OsmoticStress_regulated_NoFood
WBPaper00050990:arcade_intestinal-valve_expressed
WBPaper00050990:body-muscle_expressed
WBPaper00050990:GABAergic-neuron_expressed
WBPaper00050990:hypodermis_expressed
WBPaper00050990:intestine_expressed
WBPaper00050990:NMDA-neuron_expressed
WBPaper00050990:pharynx_expressed
WBPaper00050990:seam_expressed
WBPaper00051245:epidermis_cytoplasm_expressed
WBPaper00051245:epidermis_nucleus_expressed
WBPaper00051245:intestine_cytoplasm_expressed
WBPaper00051558:aging_regulated
WBPaper00052884:emb-4(hc60)_downregulated
WBPaper00053184:sma-2(rax5)_downregulated
WBPaper00053184:sma-4(rax3)_downregulated
WBPaper00053388:dauer_regulated_Cluster5
WBPaper00053606:N2_vs_elt-2(ca15)_upregulated
WBPaper00054410:set-26(tm2467)_downregulated
WBPaper00055626:pry-1(mu38)_upregulated
WBPaper00055648:germline_expressed
WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
WBPaper00056471:S.aureus-4h_downregulated_N2
WBPaper00056809:smn-1(ok355)_downregulated
WBPaper00057041:unc-70(cas983)_upregulated
WBPaper00057288:Cold_downregulated_transcript
WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
WBPaper00059328:mrps-5(RNAi)_downregulated_protein
WBPaper00059567:olrn-1(ums9)_regulated
WBPaper00060084:cco-1(RNAi)_downregulated_N2
WBPaper00060683:hlh-11(ko1)_downregulated
WBPaper00060811:L1_vs_adult_downregulated_neural
WBPaper00061340:g1A
WBPaper00061340:g1P
WBPaper00061340:hmc_and_homolog
WBPaper00061377:MYRF-1_interacting
WBPaper00061478:SUMO-conjugated_protein
WBPaper00061479:HDA-1_interacting_protein
WBPaper00061527:C28H8.4-ZK418.5_10918
WBPaper00061651:Coelomocyte_enriched
WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
WBPaper00062325:muscle_depleted_coding-RNA
WBPaper00062498:PPM-1.D_interacting
WBPaper00062554:MAGU-2_interacting
WBPaper00062669:extracellular-vesicle_protein
WBPaper00064071:NHR-49_interacting
WBPaper00064624:iHg-induced_aggregome
WBPaper00064992:Eugenol_upregulated
WBPaper00065120:body-muscle-transcriptome
WBPaper00065373:Cisplatin_downregulated_WT
WBPaper00065373:sek-1(km4)_downregulated_cisplatin
WBPaper00065975:P-body_vs_oocyte_enriched
WBPaper00065975:P-body_vs_WholeAnimal_enriched
cgc4386_cluster_4_5
cgc4489_group_3
WBPaper00005124:estrogen_10-5M_regulated
WBPaper00025032:cluster_65
WBPaper00025141:N2_Expressed_Genes
WBPaper00025141:unc-4::GFP_Expressed_Genes
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00026980:intestine_enriched
WBPaper00030985:Erwinia_carotovora_upregulated
WBPaper00031532:Larva_Pan_Neuronal_Depleted
WBPaper00032948:FedUp
WBPaper00035905:FBF-1_Associated
WBPaper00036123:Cadmium_regulated
WBPaper00036286:Pattern_G
WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
WBPaper00041606:CE_B.thuringiensis-DB27_regulated
WBPaper00041606:CE_S.marcescens_regulated
WBPaper00041606:CE_X.nematophila_regulated
WBPaper00045263:0.1mM-paraquat_upregulated
WBPaper00047070:N2_starvation_downregulated
WBPaper00053236:Starvation_regulated_GR1307
WBPaper00053236:Starvation_regulated_N2
[cgc5767]:expression_class_E
[cgc5767]:expression_class_E_pi(186_min)
[cgc5767]:expression_class_M
[cgc5767]:expression_class_MD
[cgc5767]:expression_class_MDE
[cgc5767]:expression_class_ME
Interaction (99)
Map_info (2)
ReferenceWBPaper00029024
WBPaper00038491
WBPaper00049828
WBPaper00055090
MethodGene