WormBase Tree Display for Gene: WBGene00021560

WBGene00021560 SMap: S_parent: Sequence: Y45G5AM
  Identity: Version: 2
    Name: CGC_name: coh-4 Person_evidence: WBPerson574
      Sequence_name: Y45G5AM.8
      Molecular_name: Y45G5AM.8a
        Y45G5AM.8a.1
        CE27409
        Y45G5AM.8b
        CE51569
        Y45G5AM.8c
        CE51556
        Y45G5AM.8b.1
        Y45G5AM.8c.1
      Other_name: CELE_Y45G5AM.8 Accession_evidence: NDB BX284605
      Public_name: coh-4
    DB_info: Database: AceView gene 5E652
        WormQTL gene WBGene00021560
        WormFlux gene WBGene00021560
        NDB locus_tag CELE_Y45G5AM.8
        NCBI gene 178818
        RefSeq protein NM_001330833.3
            NM_071760.3
            NM_001330834.3
        TrEMBL UniProtAcc A0A168HB71
            Q95XJ4
            A0A163UTM2
        UniProt_GCRP UniProtAcc Q95XJ4
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:04 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 30 Mar 2009 16:33:08 WBPerson9133 Name_change: CGC_name: coh-4
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: coh
    Allele (163)
    Strain: WBStrain00035161
      WBStrain00035162
      WBStrain00035163
      WBStrain00035164
      WBStrain00055740
    RNASeq_FPKM (74)
    GO_annotation: 00089042
    Contained_in_operon: CEOP5562
    Ortholog (20)
    Paralog: WBGene00000592 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
    Structured_description: Concise_description: coh-4 encodes a member of the Rad21/Rec8-like family of cohesion proteins known as kleisins; COH-4, along with its paralogs REC-8 and COH-3, function as members of a meiotic cohesin complex that mediates sister chromatid cohesion. Paper_evidence: WBPaper00034684
          Curator_confirmed: WBPerson1843
          Date_last_updated: 29 Nov 2010 00:00:00
      Automated_description: Involved in meiotic sister chromatid cohesion. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: Y45G5AM.8a
      Y45G5AM.8b
      Y45G5AM.8c
    Corresponding_transcript: Y45G5AM.8a.1
      Y45G5AM.8b.1
      Y45G5AM.8c.1
    Associated_feature: WBsf668649
      WBsf668856
      WBsf668857
      WBsf999747
      WBsf999748
      WBsf999749
      WBsf1019467
      WBsf233561
  Experimental_info: RNAi_result: WBRNAi00056638 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr11961
      Expr1039438
      Expr1160110
      Expr2010299
      Expr2028541
    Antibody: WBAntibody00002562
      WBAntibody00002687
    Microarray_results (12)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00037950:bodywall-muscle_L1-larva_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00038168:lin-15B(n744)_upregulated
      WBPaper00040560:hpl-2_L3_upregulated
      WBPaper00042194:nhr-114(RNAi)_upregulated
      WBPaper00044656:tatn-1(qd182)_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00045050:csr-1(hypomorph)_downregulated
      WBPaper00045050:drh-3 (ne4253)_downregulated
      WBPaper00045521:Gender_Neutral
      WBPaper00045571:germline-ablation_downregulated
      WBPaper00045774:clk-1_upregulated
      WBPaper00048611:MnCl2_downregulated
      WBPaper00048988:neuron_expressed
      WBPaper00049498:npr-1(ur89)_regulated_8
      WBPaper00049942:hsf-1(RNAi)_upregulated
      WBPaper00050080:rbr-2(tm3141)_downregulated
      WBPaper00050193:lsm-1(tm3585)_upregulated_L3
      WBPaper00050193:met-2(n4256)set-25(n5021)_upregulated_L1
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:downregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00051039:germline_enriched
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053308:SMG-2_associated_NMD(-)_unaltered_ClassII
      WBPaper00053321:PGCs_enriched_NuGen
      WBPaper00053388:dauer_regulated_Cluster2
      WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_upregulated
      WBPaper00053606:N2_vs_elt-2(ca15)_upregulated
      WBPaper00055103:thoc-5(wy822)_downregulated
      WBPaper00055354:eat-2(ad1116)_upregulated
      WBPaper00055354:Rapamycin-Allantoin_upregulated
      WBPaper00055354:Rapamycin_upregulated
      WBPaper00055354:Rifampicin-Allantoin_upregulated
      WBPaper00055648:germline_expressed
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056443:sek-1(km4)_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00057083:daf-2(e1370)rsks-1(ok1255)_post-transcriptional_upregulated
      WBPaper00057288:Cold_upregulated_transcript
      WBPaper00058598:mex-3(eu149)_downregulated
      WBPaper00058598:sin-3(tm1276)_upregulated
      WBPaper00058691:cfp-1(tm6369)_upregulated
      WBPaper00058691:sin-3(tm1276)_upregulated
      WBPaper00059356:set-6(ok2195)_baz-2(tm0235)_regulated
      WBPaper00059609:malt-1_ilc-17.1_nfki-1_downregulated
      WBPaper00059664:srbc-48(ac23)_downregulated
      WBPaper00060014:set-2(tm1630)_upregulated
      WBPaper00060014:set-2(zr2012)_upregulated
      WBPaper00060445:ikb-1(nr2027)_upregulated_L4
      WBPaper00060445:nfki-1(cer1)_upregulated_L4
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00060683:hlh-11(ko1)_downregulated
      WBPaper00060909:atfs-1(cmh15)_upregulated
      WBPaper00061203:sin-3(tm1276)_downregulated
      WBPaper00061340:M1_parent
      WBPaper00061340:OLQ_grandparent
      WBPaper00061340:RIC_parent
      WBPaper00061341:28C_24h_downregulated
      WBPaper00061902:camt-1(ok515)_regulated_RMG
      WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
      WBPaper00062056:lin-36(we36)_upregulated
      WBPaper00062056:met-2(n4256)_upregulated
      WBPaper00062159:hda-2(ok1479)_downregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00063924:PARG-1_interacting
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064716:paraquat_upregulated
      WBPaper00065975:P-body_vs_WholeAnimal_enriched
      WBPaper00065984:pals-17(syb3980)_upregulated
      WBPaper00065993:glp-1(e2141)_downregulated
      WBPaper00032165:A_to_C_transit_decreased
      WBPaper00032165:differentially_expressed_with_age_medoid_5
      WBPaper00036130:mir-243_down_regulated
      WBPaper00036286:Pattern_B
      WBPaper00036286:Pattern_H
      WBPaper00037113:Diazinon_16C_regulated
      WBPaper00040858:eQTL_age_regulated_aging
      WBPaper00040858:eQTL_regulated_juvenile
      WBPaper00040858:eQTL_regulated_old
      WBPaper00041606:CE_S.marcescens_regulated
      WBPaper00041606:CE_X.nematophila_regulated
    Interaction: WBInteraction000554911
      WBInteraction000560270
      WBInteraction000583689
      WBInteraction000584069
  Map_info: Map: V Position: -6.34419 Error: 0.01466
    Positive: Positive_clone: Y45G5AM Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (15)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene