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WormBase Tree Display for Gene: WBGene00021553

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Name Class

WBGene00021553SMapS_parentSequenceCHROMOSOME_I
IdentityVersion2
NameCGC_nametyr-5Person_evidenceWBPerson260
Sequence_nameY44E3B.2
Molecular_nameY44E3B.2
Y44E3B.2.1
CE39838
Other_nameCELE_Y44E3B.2Accession_evidenceNDBBX284601
Public_nametyr-5
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:04WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
228 Jan 2010 16:20:10WBPerson2970Name_changeCGC_nametyr-5
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classtyr
Allele (74)
RNASeq_FPKM (74)
GO_annotation00038649
00125882
Ortholog (38)
Paralog (7)
Structured_descriptionAutomated_descriptionPredicted to enable oxidoreductase activity. Human ortholog(s) of this gene implicated in several diseases, including ocular albinism 1; oculocutaneous albinism (multiple); and vitiligo. Is an ortholog of human TYR (tyrosinase).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0050633Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12442)
DOID:8465Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12442)
DOID:0070097Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12450)
DOID:0050632Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12442,HGNC:12450)
DOID:8923Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12442)
DOID:12306Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12442)
DOID:0070095Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12442)
DOID:0070094Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12442)
DOID:1909Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12442)
DOID:10123Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:12442,HGNC:12450)
Molecular_infoCorresponding_CDSY44E3B.2
Corresponding_CDS_historyY44E3B.2:wp154
Corresponding_transcriptY44E3B.2.1
Other_sequence (11)
Associated_featureWBsf983096
Experimental_infoRNAi_resultWBRNAi00112664Inferred_automaticallyRNAi_primary
WBRNAi00056562Inferred_automaticallyRNAi_primary
WBRNAi00004620Inferred_automaticallyRNAi_primary
Expr_patternExpr1020061
Expr1160035
Expr2017689
Expr2035827
Microarray_results (20)
Expression_clusterWBPaper00032031:DConiospora_upregulated_OligoArray_24h
WBPaper00033065:cyc-1(RNAi)_upregulated
WBPaper00037950:A-class-motor-neurons_L1-larva_expressed
WBPaper00037950:all-neurons_L2-larva_expressed
WBPaper00037950:AVE-neuron_L1-larva_expressed
WBPaper00037950:bodywall-muscle_L1-larva_expressed
WBPaper00037950:bodywall-muscle_L2-larva_expressed
WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
WBPaper00037950:coelomocytes_L1-larva_expressed
WBPaper00037950:coelomocytes_L2-larva_expressed
WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
WBPaper00037950:dopaminergic-neurons_larva_enriched
WBPaper00037950:excretory-cell_L2-larva_expressed
WBPaper00037950:excretory-cell_larva_enriched
WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
WBPaper00037950:hypodermis_L1-larva_expressed
WBPaper00037950:hypodermis_L3-L4-larva_expressed
WBPaper00037950:intestine_L1-larva_expressed
WBPaper00037950:intestine_L2-larva_expressed
WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
WBPaper00038438:D.coniospora_12hr_upregulated_RNAseq
WBPaper00042561:smgl-1(RNAi)_downregulated
WBPaper00044316:CH3HgCl_7.5uM_upregulated
WBPaper00044578:reduced-humidity_downregulated_microarray
WBPaper00045017:blmp-1(tm548)_upregulated
WBPaper00045521:Gender_Neutral
WBPaper00045774:clk-1_downregulated
WBPaper00045861:set-2(ok952)_upregulated
WBPaper00045861:wdr-5(ok1417)_upregulated
WBPaper00049736:15deg-then-25deg(12hr)_upregulated_N2
WBPaper00049942:HeatShock_upregulated_hsf-1(RNAi)
WBPaper00049942:hsf-1(RNAi)_upregulated
WBPaper00050231:male_enriched
WBPaper00050370:dpy-21(e428)_L3_upregulated
WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
WBPaper00050488:20C_vs_25C_regulated_mir-34(OverExpression)_adult
WBPaper00050488:20C_vs_25C_regulated_N2_adult
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050801:DAF-12_dauer_regulome
WBPaper00050801:DAF-16_dauer_regulome
WBPaper00050801:DPY-21_dauer_regulome
WBPaper00051558:aging_regulated
WBPaper00053184:sma-2(rax5)_downregulated
WBPaper00053184:sma-4(rax3)_downregulated
WBPaper00053302:zidovudine_72h_regulated
WBPaper00053308:NMD(-)_downregulated_SMD-2_non-binding_ClassIV
WBPaper00053318:mir-71(n4115)_upregulated_mRNA
WBPaper00053388:dauer_regulated_Cluster2
WBPaper00053599:oocyte_vs_mitosis_upregulated
WBPaper00053771:up_at_24h-NaCl
WBPaper00053771:up_at_dpy-7(e88)
WBPaper00055013:hmg-3(bar24)_upregulated
WBPaper00055226:ADR-2_target_N2
WBPaper00055354:eat-2(ad1116)_downregulated
WBPaper00055354:Psora-Allantoin_downregulated
WBPaper00055354:Psora_downregulated
WBPaper00055354:Rapamycin-Metformin_downregulated
WBPaper00055354:Rapamycin_downregulated
WBPaper00055354:Rifampicin-Allantoin_downregulated
WBPaper00055354:Rifampicin_downregulated
WBPaper00055648:male-vas-deferens_expressed
WBPaper00056139:soil-microbiota_downregulated
WBPaper00056809:smn-1(ok355)_upregulated
WBPaper00057041:spc-1(cas971)_upregulated
WBPaper00058955:heatshock_upregulated_CE
WBPaper00059605:MUT-16_interacting
WBPaper00059895:wounding_upregulated
WBPaper00060014:set-2(tm1630)_upregulated
WBPaper00060434:pH4.33_vs_pH6.33_downrgulated
WBPaper00060445:nfki-1(cer1)_upregulated_L1
WBPaper00060661:sensory-neuron_enriched
WBPaper00060703:nas-38(ok3407)_upregulated
WBPaper00060871:M.humicola-infection_48h_regulated
WBPaper00060909:atfs-1(cmh15)_upregulated
WBPaper00061341:28C_24h_upregulated
WBPaper00061341:28C_48h_upregulated
WBPaper00061479:hda-1(ne4752)_upregulated
WBPaper00061479:HDA-1_interacting_protein
WBPaper00061479:ubc-9(ne4833)_upregulated
WBPaper00061527:W01F3.2_1554-Y106G6D.8
WBPaper00061753:csr-1(tor159)_downregulated_20C
WBPaper00061753:csr-1(tor159)_downregulated_25C
WBPaper00062056:dpl-1(n2994)_downregulated
WBPaper00062056:lin-15B(we23)_downregulated
WBPaper00062193:skn-1(RNAi)_upregulated
WBPaper00062325:muscle_depleted_coding-RNA
WBPaper00062347:blmp-1(tm548)_upregulated
WBPaper00062354:H.zoospora_6h_regulated
WBPaper00062354:H.zoospora_12h_regulated
WBPaper00062590:Aging_downregulated_body-wall-muscle
WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
WBPaper00065841:30_2
WBPaper00065841:30_5
WBPaper00065841:34_0
WBPaper00065841:34_1
WBPaper00065993:glp-1(e2141)_downregulated
WBPaper00066232:ash-2(RNAi)_downregulated_WT
cgc4489_group_16
cgc4489_group_18
WBPaper00026629:L4_male_enriched
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00031252:AIN-2_IP_enriched
WBPaper00032948:FedUp
WBPaper00036123:Atrazine_regulated
WBPaper00036286:Pattern_F
WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.2
WBPaper00041174:environmental
WBPaper00041174:genotypic
WBPaper00041174:genotypic_and_environmental
WBPaper00044091:Bpseudomallei_induced_8h
WBPaper00044091:Bpseudomallei_induced_12h
WBPaper00044535:male_upregulated
WBPaper00045673:colistin_downregulated
WBPaper00046853:AOBr_M.aeruginosa-batch-culture_downregulated
WBPaper00049311:Ag-MNP_regulated
WBPaper00049311:AgNO3_regulated
WBPaper00049311:sAg-MNP_regulated
WBPaper00053827:pyoverdine_upregulated
[cgc6390]:male_soma-enriched
Interaction (25)
Map_infoMapIPosition-4.25528Error0.043092
PositivePositive_cloneY44E3BInferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00038491
WBPaper00055090
WBPaper00064934
WBPaper00065140
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene