WormBase Tree Display for Gene: WBGene00020842

WBGene00020842 SMap: S_parent: Sequence: T27A3
  Identity: Version: 4
    Name: CGC_name: nmrk-1 Person_evidence: WBPerson1983
      Sequence_name: T27A3.6
      Molecular_name: T27A3.6
        T27A3.6.1
        CE14227
      Other_name: moc-4 Paper_evidence: WBPaper00056452
        CELE_T27A3.6 Accession_evidence: NDB BX284601
      Public_name: nmrk-1
    DB_info: Database (13)
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:03 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 03 Apr 2017 10:56:14 WBPerson2970 Name_change: CGC_name: nmrk-1
        3 12 Aug 2019 12:44:14 WBPerson1983 Name_change: Other_name: moc-4
        4 11 Sep 2019 12:48:59 WBPerson1983 Name_change: CGC_name: nmrk-1
                Other_name: moc-4
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: nmrk
    Allele (17)
    Strain: WBStrain00032639
    RNASeq_FPKM (74)
    GO_annotation (13)
    Contained_in_operon: CEOP1300
    Ortholog (34)
    Structured_description (2)
  Disease_info: Potential_model: DOID:0111163 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:7193)
    Disease_relevance: Mutations in the human gene Molybdenum cofactor synthesis gene 2 (MOCS2; orthologous to elegans T27A3.6), are associated with Molybdenum cofactor deficiency, type B, which is an autosomal recessive disease where there is a loss of all molybdoenzyme activities, characterized by neurological damage, seizures and early childhood death. Homo sapiens Accession_evidence: OMIM 252150
              603708
          Curator_confirmed: WBPerson324
          Date_last_updated: 26 Jun 2012 00:00:00
  Molecular_info: Corresponding_CDS: T27A3.6
    Corresponding_transcript: T27A3.6.1
    Other_sequence: CBC15288_1
      CR05650
      CRC00288_1
    Associated_feature: WBsf649219
      WBsf219542
  Experimental_info: RNAi_result: WBRNAi00054263 Inferred_automatically: RNAi_primary
      WBRNAi00054264 Inferred_automatically: RNAi_primary
      WBRNAi00036016 Inferred_automatically: RNAi_primary
      WBRNAi00004319 Inferred_automatically: RNAi_primary
      WBRNAi00076715 Inferred_automatically: RNAi_primary
      WBRNAi00103547 Inferred_automatically: RNAi_primary
      WBRNAi00116636 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1012188
      Expr1039085
      Expr1157811
      Expr2014334
      Expr2032575
    Drives_construct: WBCnstr00024844
    Construct_product: WBCnstr00024844
    Microarray_results (21)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:AVA-neuron_L1-larva_expressed
      WBPaper00037950:AVE-neuron_L1-larva_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:coelomocytes_L2-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038168:lin-15B(n744)_downregulated
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00045521:Gender_Neutral
      WBPaper00045571:germline-ablation_downregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
      WBPaper00048988:neuron_expressed
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049942:hsf-1(RNAi)_downregulated
      WBPaper00050015:ifg-1(RNAi)_downregulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050801:DAF-12_dauer_regulome
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00051039:germline_enriched
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00053321:PGCs_enriched_NuGen
      WBPaper00053810:clk-1(qm30)_upregulated
      WBPaper00053810:isp-1(qm150)_upregulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00056443:sek-1(km4)_downregulated
      WBPaper00056809:smn-1(ok355)_downregulated
      WBPaper00057288:Cold_downregulated_transcript
      WBPaper00058598:sin-3(tm1276)_upregulated
      WBPaper00060014:set-2(tm1630)_upregulated
      WBPaper00060100:SiNP_downregulated_mRNA
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00061203:sin-3(tm1276)_downregulated
      WBPaper00061340:AMso_parent
      WBPaper00061340:CEPsh
      WBPaper00061340:Intestinal_and_rectal_muscle
      WBPaper00061340:Parent_of_K_Kprime
      WBPaper00061340:Pharyngeal_marginal_cell
      WBPaper00061527:lpd-2-EEED8.16
      WBPaper00062193:hsf-1(RNAi)_downregulated
      WBPaper00062193:skn-1(RNAi)_downregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062590:Aging_upregulated_coelomocyte
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064494:postdauer_upregulated_AWA
      WBPaper00064532:pals-22(jy3)_downregulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065373:Cisplatin_downregulated_WT
      WBPaper00065373:sek-1(km4)_downregulated_Ref
      WBPaper00065373:sek-1(km4)_upregulated_cisplatin
      WBPaper00065841:79_2
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00032165:differentially_expressed_with_age_medoid_5
      WBPaper00034739:N2moreDR1350
      WBPaper00035905:FBF-1_Associated
      WBPaper00036123:Cadmium_regulated
      WBPaper00036130:mir-243_down_regulated
      WBPaper00036286:Pattern_F
      WBPaper00038231:Cry5B_1.5-fold_downregulated
      WBPaper00041002:HF_3d_0.2mM_Up
      WBPaper00041002:HF_3d_2.0mM_Up
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00044091:Bpseudomallei_repressed_12h
      WBPaper00045263:0.1mM-paraquat_upregulated
      WBPaper00045263:isp-1(qm150)_upregulated
      WBPaper00045263:nuo-6(qm200)_upregulated
      WBPaper00045263:ProLongevity-mtROS_upregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_upregulated
      WBPaper00048989:N2_allantoin_upregulated
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_MD
      [cgc5767]:expression_class_MD_pd(23_min)
      [cgc5767]:expression_class_SM
      [cgc5767]:expression_class_SMD
    Interaction (55)
  Map_info: Map: I Position: 0.784315
    Positive: Positive_clone: T27A3 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00051761
    WBPaper00055090
    WBPaper00056452
    WBPaper00064339
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene