WormBase Tree Display for Gene: WBGene00020088

WBGene00020088 SMap: S_parent: Sequence: R119
  Identity: Version: 2
    Name: CGC_name: icpp-55 Person_evidence: WBPerson564
            WBPerson24683
            WBPerson50
      Sequence_name: R119.2
      Molecular_name: R119.2a
        R119.2a.1
        CE46866
        R119.2b
        CE54597
        R119.2b.1
      Other_name: CELE_R119.2 Accession_evidence: NDB BX284601
      Public_name: icpp-55
    DB_info: Database: AceView gene 1A840
        WormQTL gene WBGene00020088
        WormFlux gene WBGene00020088
        NDB locus_tag CELE_R119.2
        Panther gene CAEEL|WormBase=WBGene00020088|UniProtKB=O61710
          family PTHR43226
        NCBI gene 187899
        RefSeq protein NM_001425630.1
            NM_058324.5
        TrEMBL UniProtAcc O61710
        UniProt_GCRP UniProtAcc O61710
        OMIM gene 613553
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:02 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 13 Oct 2023 01:37:05 WBPerson51134 Name_change: CGC_name: icpp-55
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: icpp
    Allele (123)
    RNASeq_FPKM (74)
    GO_annotation: 00036140
      00036141
      00036142
      00036143
      00036144
      00036145
      00124795
      00124796
    Ortholog (36)
    Paralog: WBGene00019673 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00000155 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00003129 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00003130 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00009960 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00012075 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00021088 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00021555 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Automated_description: Predicted to enable aminopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in nephronophthisis-like nephropathy 1. Is an ortholog of human XPNPEP3 (X-prolyl aminopeptidase 3). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0111117 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:28052)
  Molecular_info: Corresponding_CDS: R119.2a
      R119.2b
    Corresponding_CDS_history: R119.2:wp102
      R119.2:wp229
    Corresponding_transcript: R119.2a.1
      R119.2b.1
    Other_sequence (43)
    Associated_feature: WBsf982479
      WBsf1009075
      WBsf218898
      WBsf218899
  Experimental_info: RNAi_result: WBRNAi00117086 Inferred_automatically: RNAi_primary
      WBRNAi00022540 Inferred_automatically: RNAi_primary
      WBRNAi00007259 Inferred_automatically: RNAi_primary
      WBRNAi00004071 Inferred_automatically: RNAi_primary
      WBRNAi00051750 Inferred_automatically: RNAi_primary
      WBRNAi00034842 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1022300
      Expr1038727
      Expr1155415
      Expr2005573
      Expr2023791
    Microarray_results (18)
    Expression_cluster: WBPaper00035073:mitochondria_protein
      WBPaper00037624:ets-4(ok165)_downregulated
      WBPaper00037950:bodywall-muscle_larva_enriched
      WBPaper00037950:bodywall-muscle_larva_SelectivelyEnriched
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00040560:hpl-2_embryo_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044760:germline_specific
      WBPaper00045417:128Q-huntingtin_upreglated
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045521:Gender_Neutral
      WBPaper00048988:neuron_expressed
      WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
      WBPaper00050726:starvation_regulated_LowSalt
      WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00051558:aging_regulated
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053295:lin-22(ot269)_downregulated
      WBPaper00053302:alovudine_72h_regulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053388:dauer_regulated_Cluster2
      WBPaper00053810:clk-1(qm30)_upregulated
      WBPaper00053810:isp-1(qm150)_upregulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00055334:DLC-1_interacting
      WBPaper00055354:Rapamycin-Metformin_upregulated
      WBPaper00055354:Rapamycin-Psora-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Rifampicin-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Rifampicin-Psora_upregulated
      WBPaper00055354:Rapamycin-Rifampicin_upregulated
      WBPaper00055354:Rifampicin-Psora_upregulated
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00055941:nuo-6(qm200);atfs-1(gk3094)_downregulated
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00056809:smn-1(ok355)_downregulated
      WBPaper00056826:SGP_biased
      WBPaper00057288:Cold_upregulated_transcript
      WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
      WBPaper00061340:Neuroblast_ASH_RIB
      WBPaper00061340:Neuroblast_I6_M5
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061527:srj-42-srw-113
      WBPaper00061902:camt-1(ok515)_regulated_RMG
      WBPaper00062156:jmjd-5(zr1234)_downregulated_germline
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00064005:starvation_upregulated_N2_mRNA
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00065158:AFD_enriched
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065993:glp-1(e2141)_downregulated
      WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00032165:differentially_expressed_with_age_medoid_7
      WBPaper00041174:environmental
      WBPaper00041174:genotypic
      WBPaper00041174:genotypic_and_environmental
    Interaction (52)
  Map_info: Map: I Position: -19.0587
    Positive: Positive_clone: R119 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00027453
    WBPaper00028327
    WBPaper00038491
    WBPaper00055090
    WBPaper00064339
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene