WormBase Tree Display for Gene: WBGene00018513

WBGene00018513 SMap: S_parent: Sequence: F46F11
  Identity: Version: 2
    Name: CGC_name: trmt-10C.1 Author_evidence: WBPerson2192
      Sequence_name: F46F11.10
      Molecular_name: F46F11.10
        F46F11.10.1
        CE39100
      Other_name: CELE_F46F11.10 Accession_evidence: NDB BX284601
      Public_name: trmt-10C.1
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:00 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 10 Jul 2023 23:47:10 WBPerson51134 Name_change: CGC_name: trmt-10C.1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: trmt
    Allele (14)
    RNASeq_FPKM (74)
    GO_annotation: 00091396
      00091397
      00091398
      00091399
      00091400
      00091401
      00091402
      00091403
      00091404
      00091405
    Contained_in_operon: CEOP1272
    Ortholog (30)
    Paralog: WBGene00009131 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00016978 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Automated_description: Predicted to enable tRNA (guanine-N1-)-methyltransferase activity and tRNA binding activity. Predicted to be involved in mitochondrial tRNA 5'-end processing and positive regulation of mitochondrial translation. Predicted to be located in mitochondrion and nucleoplasm. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 30. Is an ortholog of human TRMT10C (tRNA methyltransferase 10C, mitochondrial RNase P subunit). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0111471 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:26022)
  Molecular_info: Corresponding_CDS: F46F11.10
    Corresponding_CDS_history: F46F11.10:wp148
    Corresponding_transcript: F46F11.10.1
    Other_sequence: JI176124.1
      Acan_isotig18182
  Experimental_info: RNAi_result: WBRNAi00003688 Inferred_automatically: RNAi_primary
      WBRNAi00003687 Inferred_automatically: RNAi_primary
      WBRNAi00047529 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1023080
      Expr1151369
      Expr2003798
      Expr2022018
    Drives_construct: WBCnstr00026457
    Construct_product: WBCnstr00026457
    Microarray_results (21)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00037950:all-neurons_L1-larva_expressed
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:AVE-neuron_L1-larva_expressed
      WBPaper00037950:bodywall-muscle_L1-larva_expressed
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:coelomocytes_L2-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00040221:DAF-12_target_ALF4
      WBPaper00042561:smg-2(RNAi)_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044760:germline_specific
      WBPaper00045050:csr-1(hypomorph)_downregulated
      WBPaper00045521:Gender_Neutral
      WBPaper00048988:neuron_expressed
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049920:Glucose-Diet_downregulated_hyl-2(tm2031)
      WBPaper00050234:lin-28(RNAi)_upregulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00051039:germline_enriched
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053321:PGCs_enriched_NuGen
      WBPaper00054758:alg-1(gk204)_downregulated
      WBPaper00055354:Rapamycin-Allantoin_upregulated
      WBPaper00055482:pmt-2(RNAi)_downregulated
      WBPaper00055648:germline_expressed
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056826:SGP_biased
      WBPaper00056868:P.aeruginosa_upregulated_smallRNA
      WBPaper00057288:Cold_downregulated_transcript
      WBPaper00058598:sin-3(tm1276)_upregulated
      WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
      WBPaper00060100:SiNP_downregulated_mRNA
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060661:hypoxia_upregulated
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00061203:let-418(n3536)_downregulated
      WBPaper00061203:sin-3(tm1276)_downregulated
      WBPaper00061203:spr-1(ok2144)_downregulated
      WBPaper00061439:unc-30(ok613)_downregulated
      WBPaper00061527:ima-1_20458-bath-41
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064716:paraquat_upregulated
      WBPaper00065096:Day10_vs_Day1_upregulated
      WBPaper00065975:P-body_vs_WholeAnimal_enriched
      WBPaper00065993:glp-1(e2141)_downregulated
      WBPaper00066110:tetraploid_vs_diploid_downregulated
      WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
      cgc4489_group_2
      WBPaper00025032:cluster_8
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00032165:A_to_C_transit_decreased
      WBPaper00032165:differentially_expressed_with_age_medoid_5
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00035905:FBF-1_Associated
      WBPaper00036123:Atrazine_regulated
      WBPaper00036130:mir-243_down_regulated
      WBPaper00036286:Pattern_B
      WBPaper00037611:GLD-2-associated
      WBPaper00037695:LD_3-day
      WBPaper00040858:eQTL_regulated_old
      WBPaper00040963:TA300_down
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00045263:0.1mM-paraquat_upregulated
      WBPaper00045263:nuo-6(qm200)_upregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_upregulated
      WBPaper00048989:N2_allantoin_upregulated
      [cgc5767]:cluster_1
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_MD
      [cgc5767]:expression_class_MD_pd(PC32)
      [cgc5767]:expression_class_SM
      [cgc5767]:expression_class_SMD
      [cgc6390]:Cluster_F
      [cgc6390]:intrinsic
      [cgc6390]:oogenesis-enriched
    Interaction: WBInteraction000239624
      WBInteraction000581064
  Map_info: Positive: Positive_clone: F46F11 Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: I 0.278304
  Reference: WBPaper00038491
    WBPaper00055090
  Method: Gene