WormBase Tree Display for Gene: WBGene00017349

WBGene00017349 SMap: S_parent: Sequence: F10E7
  Identity: Version: 2
    Name: CGC_name: farl-11 Person_evidence: WBPerson3760
            WBPerson75
      Sequence_name: F10E7.8
      Molecular_name (9)
      Other_name: CELE_F10E7.8 Accession_evidence: NDB BX284602
      Public_name: farl-11
    DB_info: Database: AceView gene 2H392
        WormQTL gene WBGene00017349
        WormFlux gene WBGene00017349
        NDB locus_tag CELE_F10E7.8
        Panther gene CAEEL|WormBase=WBGene00017349|UniProtKB=A0A1D3PCL0
          family PTHR13239
        NCBI gene 174165
        RefSeq protein NM_063066.9
            NM_001346631.3
            NM_001346630.2
        TrEMBL UniProtAcc A0A1D3PD01
            A0A1D3PCL0
            Q19300
        UniProt_GCRP UniProtAcc A0A1D3PCL0
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:30:58 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 18 Apr 2008 13:26:44 WBPerson2970 Name_change: CGC_name: farl-11
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: farl
    Allele (35)
    RNASeq_FPKM (74)
    GO_annotation (7)
    Contained_in_operon: CEOP2288
    Ortholog (39)
    Structured_description: Concise_description: farl-11 is an ortholog of human STRIP2 (striatin interacting protein 2) and STRIP1 (striatin interacting protein 1); FARL-11 is required for normal ER dynamics and the membrane localization of GLP-1 in the germline; translation of farl-11 mRNA in the mitotic germline is promoted by PUF-8; FARL-11::GFP expressed under the endogenous promoter and 3' UTR localizes to endoplasmic reticulum and the nuclear membrane in the germline and embryos. Paper_evidence: WBPaper00049965
          Person_evidence: WBPerson2530
          Curator_confirmed: WBPerson324
          Date_last_updated: 15 Dec 2016 00:00:00
      Automated_description: Involved in endoplasmic reticulum organization; epithelial tube morphogenesis; and positive regulation of endocytic recycling. Located in endoplasmic reticulum. Expressed in germ line. Is an ortholog of human STRIP1 (striatin interacting protein 1) and STRIP2 (striatin interacting protein 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F10E7.8a
      F10E7.8b
      F10E7.8c
    Corresponding_CDS_history: F10E7.8:wp203
    Corresponding_transcript: F10E7.8a.1
      F10E7.8b.1
      F10E7.8c.1
    Other_sequence (56)
    Associated_feature (11)
  Experimental_info: RNAi_result: WBRNAi00022322 Inferred_automatically: RNAi_primary
      WBRNAi00076290 Inferred_automatically: RNAi_primary
      WBRNAi00044263 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr4805
      Expr13023
      Expr1022554
      Expr1037459
      Expr1148221
      Expr2011429
      Expr2029667
    Drives_construct: WBCnstr00027366
      WBCnstr00038374
    Construct_product: WBCnstr00001417
      WBCnstr00027366
      WBCnstr00038374
    Microarray_results (19)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00032528:L3_enriched
      WBPaper00036375:enriched_in_PVD_OLL
      WBPaper00040221:DAF-12_target_ALF4
      WBPaper00042194:nhr-114(RNAi)_upregulated
      WBPaper00044656:tatn-1(qd182)_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045521:Gender_Neutral
      WBPaper00045774:clk-1_downregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00048988:neuron_expressed
      WBPaper00049498:npr-1(ur89)_regulated_6
      WBPaper00049920:Glucose-Diet_downregulated_hyl-2(tm2031)
      WBPaper00049942:HeatShock_upregulated_hsf-1(RNAi)
      WBPaper00049942:hsf-1(RNAi)_upregulated
      WBPaper00050344:PLM-neuron_enriched
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00050990:seam_expressed
      WBPaper00051039:ash-2(RNAi)_regulated_intestine
      WBPaper00051039:germline_enriched
      WBPaper00051257:Levamisole_upregulated
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053295:lin-22(icb38)_downregulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053308:SMG-2_associated_NMD(-)_unaltered_ClassII
      WBPaper00053713:Pheromone-induced_postdauer_vs_control_upregulated
      WBPaper00053810:daf-2(e1370)_downregulated
      WBPaper00053810:isp-1(qm150)_downregulated
      WBPaper00053810:nuo-6(qm200)_downregulated
      WBPaper00055226:ADR-2_target_N2
      WBPaper00055334:DLC-1_interacting
      WBPaper00055648:germline_expressed
      WBPaper00055971:nhl-2(ok818)_25C_downregulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056275:P.aeruginosa_downregulated
      WBPaper00056443:sek-1(km4)_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00056809:smn-1(ok355)_downregulated
      WBPaper00058725:sftb-1(cer6)_downregulated
      WBPaper00058725:sftb-1(cer39)_downregulated
      WBPaper00059174:MEG-3_interacting
      WBPaper00059356:BAZ-2_SET-6_interacting
      WBPaper00059664:srbc-48(ac23)_downregulated
      WBPaper00059763:neuron_expressed
      WBPaper00059895:wounding_downregulated
      WBPaper00059987:Wounding_downregulated
      WBPaper00060014:set-2(zr2012)_downregulated
      WBPaper00060084:cco-1(RNAi)_downregulated_lin-40(yth27)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060683:hlh-11(ko1)_downregulated
      WBPaper00060911:prx-5(RNAi)_downregulated_protein
      WBPaper00061340:Parent_of_exc_duct_pore_DB_1_3
      WBPaper00061439:unc-30(ok613)_downregulated
      WBPaper00061439:unc-30(ok613)_downregulated_P.aeruginosa-infection
      WBPaper00061527:cids-2_2203-attf-2_2451
      WBPaper00061527:npp-6-mtr-4_21425
      WBPaper00062193:hsf-1(RNAi)_downregulated
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064055:trl-1(cas1077)_upregulated_non-starved
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064539:nhr-114(gk849)_downregulated
      WBPaper00064716:paraquat_upregulated
      WBPaper00064871:hypoxia_upregulated_F1
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065841:48_0
      WBPaper00065993:glp-1(e2141)_downregulated
      WBPaper00066062:xrep-4(lax137)_upregulated
      WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00031003:hlh_1_enriched
      WBPaper00035227:heat_shock_regulated
      WBPaper00035560:ahr-1_downregulated
      WBPaper00035905:FBF-1_Associated
      WBPaper00036130:mir-243_down_regulated
      WBPaper00036286:Pattern_G
      WBPaper00037901:GLD-1_mRNA_targets
      WBPaper00038060:SUMO-1_upregulated
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040823:alg-1(gk214)_downregulated
      WBPaper00041002:HQ_3d_2.0mM_Down
      WBPaper00041606:CE_S.marcescens_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_EtBr-exposed_24h
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_24h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_24h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_24h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00042128:gei-8(ok1671)_downregulated
      WBPaper00042204:Comamonas_DA1877_downregulated
      WBPaper00042258:DA1877_downregulated_GravidAdult
      WBPaper00042258:DA1877_downregulated_YoungAdult
      WBPaper00048563:L1_DD_enriched
      WBPaper00048624:hlh-25(ok1710)_upregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00055435:AuNPs_downregulated
      WBPaper00055435:MUA-AuNP-0.5_downregulated
      WBPaper00055435:MUA-AuNP-3_downregulated
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_SM
      [cgc6390]:Cluster_F
      [cgc6390]:intrinsic
    Interaction (57)
  Map_info: Map: II Position: 0.494201 Error: 0.00019
    Positive: Positive_clone: F10E7 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00030897
    WBPaper00038491
    WBPaper00047481
    WBPaper00048228
    WBPaper00049965
    WBPaper00052206
    WBPaper00055090
    WBPaper00062623
    WBPaper00063115
    WBPaper00065585
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene