WormBase Tree Display for Gene: WBGene00013875

WBGene00013875 SMap: S_parent: Sequence: CHROMOSOME_V
  Identity: Version: 2
    Name: CGC_name: cest-2.1 Person_evidence: WBPerson36909
            WBPerson7188
      Sequence_name: ZC376.3
      Molecular_name: ZC376.3
        ZC376.3.1
        CE41968
      Other_name: CELE_ZC376.3 Accession_evidence: NDB BX284605
      Public_name: cest-2.1
    DB_info: Database: AceView gene 5O650
        WormQTL gene WBGene00013875
        WormFlux gene WBGene00013875
        NDB locus_tag CELE_ZC376.3
        Panther gene CAEEL|WormBase=WBGene00013875|UniProtKB=G5EDJ7
          family PTHR11559
        NCBI gene 179916
        RefSeq protein NM_074107.6
        TrEMBL UniProtAcc G5EDJ7
        UniProt_GCRP UniProtAcc G5EDJ7
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:55 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 20 May 2019 14:10:26 WBPerson1983 Name_change: CGC_name: cest-2.1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: cest
    Allele (45)
    Strain: WBStrain00037757
    RNASeq_FPKM (74)
    GO_annotation: 00014127
    Ortholog (73)
    Paralog (41)
    Structured_description: Automated_description: Predicted to be located in membrane. Human ortholog(s) of this gene implicated in colorectal cancer; hepatocellular carcinoma; and stomach cancer. Is an ortholog of human CES1 (carboxylesterase 1) and CES4A (carboxylesterase 4A). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:9256 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1863)
      DOID:3119 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1863)
      DOID:10534 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1863)
      DOID:684 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1863)
  Molecular_info (4)
  Experimental_info: RNAi_result: WBRNAi00021661 Inferred_automatically: RNAi_primary
      WBRNAi00058857 Inferred_automatically: RNAi_primary
      WBRNAi00038027 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1027801
      Expr1036206
      Expr1162300
      Expr2008611
      Expr2026847
    Drives_construct: WBCnstr00029484
    Construct_product: WBCnstr00029484
    Microarray_results (19)
    Expression_cluster: WBPaper00037950:A-class-motor-neurons_L1-larva_expressed
      WBPaper00037950:AVA-neuron_L1-larva_expressed
      WBPaper00037950:AVE-neuron_L1-larva_expressed
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:bodywall-muscle_L1-larva_expressed
      WBPaper00037950:coelomocytes_L1-larva_expressed
      WBPaper00037950:coelomocytes_L2-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:intestine_embryo_enriched
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00038168:lin-15B(n744)_downregulated
      WBPaper00038438:P.lumniescens_24hr_downregulated_TilingArray
      WBPaper00042561:smgl-1(RNAi)_downregulated
      WBPaper00044030:nhr-8(hd117)_downregulated
      WBPaper00044037:eat-2_downregulated
      WBPaper00044316:CH3HgCl_7.5uM_downregulated
      WBPaper00044736:oscillating_dev_expression
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
      WBPaper00045401:N.parisii_64h_downregulated
      WBPaper00045571:germline-ablation_upregulated
      WBPaper00046121:endoderm_unique
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00046499:AMPK_regulated
      WBPaper00048926:miaserin_upregulated_adult-day5
      WBPaper00048988:neuron_expressed
      WBPaper00049134:hpk-1(pk1393)_downregulated
      WBPaper00049484:elt-2(RNAi)_downregulated_L4
      WBPaper00049498:npr-1(ur89)_regulated_3
      WBPaper00049545:jmjd-3.1(+)_upregulated
      WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_upregulated
      WBPaper00049942:HeatShock_downregulated_hsf-1(RNAi)
      WBPaper00049942:hsf-1(RNAi)_downregulated
      WBPaper00049954:BPA_upregulated
      WBPaper00050080:rbr-2(tm3141)_upregulated
      WBPaper00050332:skn-1(RNAi)_downregulated
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050990:intestine_enriched
      WBPaper00050990:intestine_expressed
      WBPaper00051039:intestine_enriched
      WBPaper00051257:Levamisole_upregulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053388:dauer_regulated_Cluster5
      WBPaper00053402:his-3(RNAi)_downregulated
      WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_downregulated
      WBPaper00053606:N2_vs_elt-2(ca15)_downregulated
      WBPaper00053810:daf-2(e1370)_downregulated
      WBPaper00054872:egl-9(sa307)_downregulated
      WBPaper00056034:pals-22(jy3)_downregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056161:male_enriched_siRNA
      WBPaper00056167:ifo-1(kc2)_upregulated
      WBPaper00056169:rrf-3(pk1426)_downregulated_L1
      WBPaper00056284:ints-2(RNAi)_downregulated
      WBPaper00056326:zip-3(gk3164)_upregulated_P.aeruginosa-infected
      WBPaper00056443:sek-1(km4)_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056809:smn-1(ok355)_downregulated
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057041:unc-70(cas983)_downregulated
      WBPaper00057068:Cadmium_downregulated
      WBPaper00057068:ints-4(RNAi)_downregulated
      WBPaper00058665:graphene-oxide_upregulated_mRNA
      WBPaper00058691:cfp-1(tm6369)_downregulated
      WBPaper00058969:RIS_depleted
      WBPaper00059253:stearic-acid_upregulated
      WBPaper00059253:sucrose_stearic-acid_upregulated
      WBPaper00059253:sucrose_upregulated
      WBPaper00059334:SACY-1_interacting
      WBPaper00059378:cec-4(ok3124);lmn-1(Y59C)_vs_lmn-1(Y59C)_upregulated
      WBPaper00059839:S.maltophilia_regulated
      WBPaper00060084:cco-1(RNAi)_downregulated_lin-40(yth27)
      WBPaper00060358:B.thuringiensis_non-pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060661:hypoxia_downregulated
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00060764:swsn-1(os22ts)_downregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060909:atfs-1(et18)_upregulated
      WBPaper00061007:HB101_upregulated
      WBPaper00061007:HB115_upregulated
      WBPaper00061007:S.aquatilis_upregulated
      WBPaper00061340:Intestine
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061341:28C_48h_downregulated
      WBPaper00061439:unc-30(ok613)_downregulated
      WBPaper00061527:T24C12.3-C01G10.9
      WBPaper00061530:nhr-49(e2144)_downregulated
      WBPaper00061699:daf-18(ok480)_downregulated
      WBPaper00061753:csr-1(tor159)_upregulated_25C
      WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
      WBPaper00062056:lin-37(n758)_downregulated
      WBPaper00062159:hda-2(ok1479)_downregulated
      WBPaper00062197:mec-8_upregulated_TRN
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062345:bortezomib_4h_downregulated_N2
      WBPaper00062345:bortezomib_4h_downregulated_zip-1(jy13)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064107:lin-35(n745)_downregulated
      WBPaper00064229:B.thuringiensis-Cry5Ba_upregulated
      WBPaper00064532:pals-22(jy3)_downregulated
      WBPaper00064602:egl-9(sa307)_downregulated
      WBPaper00064716:paraquat_downregulated
      WBPaper00064933:bcf-1(ylf1)_downregulated_transcript
      WBPaper00064939:vit-5(RNAi)_upregulated
      WBPaper00065086:JU1400_N.ausubeli_regulated
      WBPaper00065086:JU1400_N.ferruginous_regulated
      WBPaper00065086:N2_N.ausubeli_regulated
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065835:Day11_vs_Day1_downregulated
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065984:pals-17(syb3980)_downregulated
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      WBPaper00025032:cluster_5
      WBPaper00029437:dcr-1_upregulated
      WBPaper00029437:rde-4_upregulated
      WBPaper00032165:differentially_expressed_with_age_medoid_4
      WBPaper00032948:StarveUp3
      WBPaper00033099:organophosphorus_pesticide_regulated
      WBPaper00035588:alg-1(-)_upregulated
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00035892:Y.pestis_regulated
      WBPaper00036123:Atrazine_regulated
      WBPaper00036286:Pattern_I
      WBPaper00037695:WC_5-day
      WBPaper00038172:crh-1null_down_regulated
      WBPaper00038172:tax-6null_down_regulated
      WBPaper00038231:Cry5B_1.5-fold_downregulated
      WBPaper00038231:Cry5B_2-fold_downregulated
      WBPaper00038462:aging_downregulated
      WBPaper00040210:Chlorpyrifos_24C_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041960:N2_fasting_upregulated_9hto12h
      WBPaper00041960:N2_fasting_upregulated_anytime
      WBPaper00044535:male_downregulated
      WBPaper00045263:0.1mM-paraquat_downregulated
      WBPaper00045960:L4-lethargus_upregulated
      WBPaper00047070:N2_UV_downregulated
      WBPaper00049311:Ag-MNP_regulated
      WBPaper00053236:daf-16(mgDF50)_regulated_Starved
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00053550:daf-19(m86)_upregulated_L1
      WBPaper00055899:2,4-Dinitroanisole_regulated
      [cgc5767]:cluster_4
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_E_pi(66_min)
      [cgc5767]:expression_class_SE
      [cgc5767]:expression_class_SE_pi(66_min)
      [cgc6390]:Cluster_B
      [cgc6390]:herm_soma-enriched
    Interaction: WBInteraction000242412
      WBInteraction000253168
      WBInteraction000253208
      WBInteraction000399404
      WBInteraction000561001
      WBInteraction000564451
      WBInteraction000566912
  Map_info: Map: V Position: 6.18506
    Positive: Positive_clone: ZC376 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00033099
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene