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WormBase Tree Display for Gene: WBGene00012967

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Name Class

WBGene00012967SMapS_parentSequenceY48A6B
IdentityVersion2
NameCGC_namekvs-4Person_evidenceWBPerson260
WBPerson145
Sequence_nameY48A6B.6
Molecular_name (9)
Other_nameCELE_Y48A6B.6Accession_evidenceNDBBX284603
Public_namekvs-4
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:54WBPerson1971EventImportedInitial conversion from CDS class of WS125
229 Jul 2011 16:30:08WBPerson2970Name_changeCGC_namekvs-4
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classkvs
Allele (189)
StrainWBStrain00055287
RNASeq_FPKM (74)
GO_annotation (27)
Contained_in_operonCEOP3712
Ortholog (54)
Paralog (13)
Structured_descriptionAutomated_descriptionPredicted to enable delayed rectifier potassium channel activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to be located in axon; plasma membrane; and somatodendritic compartment. Predicted to be part of voltage-gated potassium channel complex. Expressed in AVA and nervous system. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 26. Is an ortholog of human KCNF1 (potassium voltage-gated channel modifier subfamily F member 1) and KCNS2 (potassium voltage-gated channel modifier subfamily S member 2).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0080461Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:6231)
DOID:1826Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:6231)
Molecular_infoCorresponding_CDSY48A6B.6a
Y48A6B.6b
Y48A6B.6c
Corresponding_CDS_historyY48A6B.6:wp88
Y48A6B.6a:wp120
Y48A6B.6b:wp275
Corresponding_transcriptY48A6B.6a.1
Y48A6B.6b.1
Y48A6B.6c.1
Other_sequence (24)
Associated_featureWBsf994239
WBsf994240
WBsf1015905
WBsf1015906
Experimental_infoRNAi_resultWBRNAi00006209Inferred_automaticallyRNAi_primary
WBRNAi00037221Inferred_automaticallyRNAi_primary
WBRNAi00006717Inferred_automaticallyRNAi_primary
WBRNAi00056866Inferred_automaticallyRNAi_primary
WBRNAi00020727Inferred_automaticallyRNAi_primary
WBRNAi00056865Inferred_automaticallyRNAi_primary
Expr_patternExpr12745
Expr12746
Expr15545
Expr1024741
Expr1160318
Expr2012987
Expr2031219
Drives_constructWBCnstr00022466
Construct_productWBCnstr00022463
WBCnstr00022727
Microarray_results (24)
Expression_clusterWBPaper00037950:A-class-motor-neurons_L2-larva_expressed
WBPaper00037950:all-neurons_L1-larva_expressed
WBPaper00037950:all-neurons_L2-larva_expressed
WBPaper00037950:all-neurons_larva_enriched
WBPaper00037950:all-neurons_larva_SelectivelyEnriched
WBPaper00037950:bodywall-muscle_L1-larva_expressed
WBPaper00037950:coelomocytes_L2-larva_expressed
WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
WBPaper00037950:germline-precursors_blastula-embryo_expressed
WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
WBPaper00038438:Harposporium_24hr_downregulated_RNAseq
WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
WBPaper00040420:ALM_PLM_enriched
WBPaper00044736:flat_dev_expression
WBPaper00045521:Gender_Neutral
WBPaper00046805:csr-1(RNAi)_upregulated_Set1
WBPaper00048988:neuron_enriched
WBPaper00048988:neuron_expressed
WBPaper00049626:UNC-75_target
WBPaper00049942:HeatShock_downregulated_hsf-1(RNAi)
WBPaper00049942:hsf-1(RNAi)_downregulated
WBPaper00050163:chd-3(eh4);let-418(RNAi)_upregulated_100-cell-embryo
WBPaper00050344:AFD-neuron_enriched
WBPaper00050344:ASER-neuron_enriched
WBPaper00050344:PLM-neuron_enriched
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
WBPaper00053308:SMG-2_associated_NMD(-)_unaltered_ClassII
WBPaper00055103:thoc-5(wy822)_upregulated
WBPaper00055226:ADR-2_target_N2
WBPaper00055354:eat-2(ad1116)_downregulated
WBPaper00055354:Rapamycin-Metformin_downregulated
WBPaper00055354:Rapamycin-Psora-Allantoin_downregulated
WBPaper00055354:Rapamycin-Rifampicin-Allantoin_downregulated
WBPaper00055354:Rapamycin-Rifampicin_downregulated
WBPaper00055565:AVK_enriched
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
WBPaper00056855:his-72(uge40)_upregulated
WBPaper00057068:ints-4(RNAi)_upregulated
WBPaper00057140:meg-3(tm4259)_meg-4(ax2026)_downregulated
WBPaper00057161:meg-3(tm4259)_meg-4(ax2026)_downregulated_endo-siRNA_targets
WBPaper00057288:iff-1(RNAi)_upregulated_transcript
WBPaper00058969:RIS_enriched
WBPaper00059027:neuron-synapses_depleted
WBPaper00059440:GLP-1_represseded
WBPaper00059440:LAG-1_repressed_48hr-auxin
WBPaper00060459:bcat-1(RNAi)_upregulated
WBPaper00060661:sensory-neuron_enriched
WBPaper00060811:L1_vs_adult_upregulated_neural
WBPaper00060886:met-2(n4256)_upregulated
WBPaper00061340:ASJ
WBPaper00061340:XXX
WBPaper00061341:28C_24h_upregulated
WBPaper00061341:28C_48h_upregulated
WBPaper00061479:hda-1(ne4752)_upregulated
WBPaper00061527:acy-2-F35C5.11
WBPaper00061651:ADL_enriched
WBPaper00061651:ALM_enriched
WBPaper00061651:AVM_enriched
WBPaper00061651:PLM_enriched
WBPaper00061651:PVM_enriched
WBPaper00061753:csr-1(tor159)_upregulated_25C
WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
WBPaper00062056:met-2(n4256)_upregulated
WBPaper00062103:neuron_enriched
WBPaper00062159:hda-2(ok1479)_upregulated
WBPaper00062325:muscle_depleted_coding-RNA
WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20)
WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
WBPaper00065841:20_0
WBPaper00065841:20_1
WBPaper00065841:20_2
WBPaper00065841:35_0
WBPaper00065841:35_2
WBPaper00065841:35_3
WBPaper00065841:44_1
WBPaper00065841:54_0
WBPaper00065841:81_0
WBPaper00065841:84_0
WBPaper00065841:101_0
WBPaper00065841:105_0
WBPaper00065841:106_0
WBPaper00066110:Cisplatin_upregulated_tetraploid
cgc4489_group_25
WBPaper00024671:AFD_AWB_vs_unsorted_upregulated
WBPaper00026929:Resveratrol_regulated_daf-16
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00026980:intestine_enriched
WBPaper00030839:Larval_Pan_Neuronal
WBPaper00030985:Erwinia_carotovora_upregulated
WBPaper00031532:Larva_Pan_Neuronal_Enriched
WBPaper00032062:age_regulated_genes
WBPaper00036375:depleted_in_PVD_OLL
WBPaper00041174:genotypic
WBPaper00041174:genotypic_prime
WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
WBPaper00044091:Bpseudomallei_induced_8h
WBPaper00045807:microcystin-LR_upregulated
WBPaper00045960:L1-L4-lethargus_upregulated
WBPaper00045960:L4-lethargus_upregulated
WBPaper00053236:Starvation_regulated_GR1307
[cgc5376]:let-60(G12V)-regulated_genes
Interaction (17)
Map_infoMapIIIPosition5.85665Error0.005556
PositivePositive_cloneY48A6BInferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00027009
WBPaper00038491
WBPaper00049107
WBPaper00055090
WBPaper00062255
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene