WormBase Tree Display for Gene: WBGene00012527

WBGene00012527 SMap: S_parent: Sequence: Y32F6A
  Identity: Version: 2
    Name: CGC_name: set-22 Person_evidence: WBPerson1730
            WBPerson268
            WBPerson632
      Sequence_name: Y32F6A.1
      Molecular_name: Y32F6A.1
        Y32F6A.1.1
        CE20203
        Y32F6A.1.2
      Other_name: CELE_Y32F6A.1 Accession_evidence: NDB BX284605
      Public_name: set-22
    DB_info: Database: AceView gene 5K921
        WormQTL gene WBGene00012527
        WormFlux gene WBGene00012527
        NDB locus_tag CELE_Y32F6A.1
        NCBI gene 179457
        RefSeq protein NM_001392594.1
        TREEFAM TREEFAM_ID TF316282
        TrEMBL UniProtAcc Q9XXS2
        UniProt_GCRP UniProtAcc Q9XXS2
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:53 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 03 May 2007 10:33:07 WBPerson2970 Name_change: CGC_name: set-22
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: set
    Allele (69)
    Strain: WBStrain00032522
    RNASeq_FPKM (74)
    Contained_in_operon: CEOP5558
    Ortholog (18)
    Structured_description: Concise_description: set-22 encodes a SET domain-containing protein with no non-nematode orthologs; neither set-22(n5015) nor set-22(RNAi) have any obvious phenotypes. Paper_evidence: WBPaper00030864
          Curator_confirmed: WBPerson567
          Date_last_updated: 11 Oct 2007 00:00:00
      Automated_description: Enriched in several structures, including ABalapppaa; AFD; germ line; germline precursor cell; and head mesodermal cell based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including skn-1; glp-1; and age-1 based on microarray; tiling array; and RNA-seq studies. Is affected by thirteen chemicals including rotenone; manganese chloride; and D-glucose based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SET domain superfamily and SET domain. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: Y32F6A.1
    Corresponding_transcript: Y32F6A.1.1
      Y32F6A.1.2
    Other_sequence (3)
    Associated_feature: WBsf647156
  Experimental_info: RNAi_result: WBRNAi00020174 Inferred_automatically: RNAi_primary
      WBRNAi00082705 Inferred_automatically: RNAi_primary
      WBRNAi00091509 Inferred_automatically: RNAi_primary
      WBRNAi00113455 Inferred_automatically: RNAi_primary
      WBRNAi00001475 Inferred_automatically: RNAi_primary
      WBRNAi00055782 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr14370
      Expr1014637
      Expr1035542
      Expr1159315
      Expr2015767
      Expr2034000
    Drives_construct: WBCnstr00029924
    Construct_product: WBCnstr00029924
    Microarray_results (21)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00032097:CGH-1-associated-mRNA
      WBPaper00033065:cyc-1(RNAi)_downregulated
      WBPaper00035211:age-1_vs_N2_downregulated
      WBPaper00035269:cde-1_regulated
      WBPaper00037950:germline-precursors_embryo_enriched
      WBPaper00037950:germline-precursors_embryo_SelectivelyEnriched
      WBPaper00040221:DAF-12_target_ALF4
      WBPaper00042194:nhr-114(RNAi)_upregulated
      WBPaper00042477:rsr-2(RNAi)_downregulated_TilingArray
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044656:tatn-1(qd182)_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_downregulated
      WBPaper00045050:drh-3 (ne4253)_downregulated
      WBPaper00045521:Gender_Neutral
      WBPaper00045571:germline-ablation_downregulated
      WBPaper00047132:skn-1(RNAi)_downregulated_glp-1(ts)-dependent
      WBPaper00048611:MnCl2_downregulated
      WBPaper00048988:neuron_expressed
      WBPaper00049920:Glucose-Diet_downregulated_hyl-2(tm2031)
      WBPaper00049942:hsf-1(RNAi)_downregulated
      WBPaper00049954:BPS_downregulated
      WBPaper00050234:lin-28(RNAi)_upregulated
      WBPaper00050344:AFD-neuron_enriched
      WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
      WBPaper00050488:20C_vs_25C_regulated_mir-34(OverExpression)_adult
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:downregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050990:intestine_enriched
      WBPaper00050990:intestine_expressed
      WBPaper00051039:germline_enriched
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053295:lin-22(icb38)_downregulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053321:PGCs_enriched_NuGen
      WBPaper00053388:dauer_regulated_Cluster2
      WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_upregulated
      WBPaper00053606:N2_vs_elt-2(ca15)_upregulated
      WBPaper00054493:hpl-2(tm1489)_downregulated
      WBPaper00054758:alg-1(gk204)_downregulated
      WBPaper00055103:thoc-5(wy822)_downregulated
      WBPaper00055354:eat-2(ad1116)_upregulated
      WBPaper00055354:Metformin_downregulated
      WBPaper00055354:Rapamycin-Allantoin_upregulated
      WBPaper00055354:Rapamycin_upregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055482:pmt-2(RNAi)_downregulated
      WBPaper00055648:germline_expressed
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00056034:pals-22(jy3)_downregulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056826:hmc_biased
      WBPaper00057041:spc-1(cas971)_upregulated
      WBPaper00057288:Cold_upregulated_transcript
      WBPaper00057288:iff-1(RNAi)_upregulated_transcript
      WBPaper00058598:mex-1(or286)_downregulated
      WBPaper00058598:mex-3(eu149)_downregulated
      WBPaper00058598:sin-3(tm1276)_upregulated
      WBPaper00058725:sftb-1(cer39)_downregulated
      WBPaper00058958:100mGy-irradiation-72h_downregulated
      WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
      WBPaper00059356:set-6(ok2195)_baz-2(tm0235)_regulated
      WBPaper00059664:srbc-48(ac23)_downregulated
      WBPaper00059895:wounding_downregulated
      WBPaper00060014:set-2(tm1630)_upregulated
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060445:ikb-1(nr2027)_upregulated_L4
      WBPaper00060445:nfki-1(cer1)_ikb-1(nr2027)_upregulated_L4
      WBPaper00060445:nfki-1(cer1)_upregulated_L4
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00060683:hlh-11(ko1)_downregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060909:atfs-1(cmh15)_upregulated
      WBPaper00061007:S.aquatilis_downregulated
      WBPaper00061203:sin-3(tm1276)_downregulated
      WBPaper00061203:spr-1(ok2144)_downregulated
      WBPaper00061274:hypergravity_10xg_upregulated
      WBPaper00061274:hypergravity_15xg_upregulated
      WBPaper00061340:Neuroblast_ALA_RMED
      WBPaper00061439:unc-30(ok613)_downregulated
      WBPaper00061439:unc-30(ok613)_downregulated_P.aeruginosa-infection
      WBPaper00061527:T22D1.5-inx-14
      WBPaper00062159:hda-2(ok1479)_downregulated
      WBPaper00062193:hsf-1(RNAi)_downregulated
      WBPaper00062193:skn-1(RNAi)_downregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062354:H.zoospora_6h_regulated
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064315:mrg-1(qa6200)_downregulated_PGCs
      WBPaper00064502:spe-44(fx110)_upregulated
      WBPaper00064716:paraquat_upregulated
      WBPaper00065005:sams-4(RNAi)_downregulated
      WBPaper00065096:25C_vs_20C_upregulated
      WBPaper00065096:Day10_vs_Day1_upregulated
      WBPaper00065975:P-body_vs_oocyte_enriched
      WBPaper00065975:P-body_vs_WholeAnimal_enriched
      WBPaper00065984:pals-17(syb3980)_upregulated
      WBPaper00065993:glp-1(e2141)_downregulated
      WBPaper00066110:tetraploid_vs_diploid_downregulated
      WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
      cgc4489_group_2
      WBPaper00005124:testosterone_10-9M_regulated
      WBPaper00025032:cluster_3
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00035905:FBF-1_Associated
      WBPaper00036130:mir-243_down_regulated
      WBPaper00036286:Pattern_B
      WBPaper00036429:glp-1(oz112)_upregulated
      WBPaper00037611:RNP-8-associated
      WBPaper00038427:lin-54_embryo_changed
      WBPaper00040858:eQTL_age_regulated_developing
      WBPaper00040858:eQTL_regulated_developing
      WBPaper00040858:eQTL_regulated_juvenile
      WBPaper00040963:TA300_down
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_S.marcescens_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_EtBr-exposed_51h
      WBPaper00045263:0.1mM-paraquat_upregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_upregulated
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00056330:mrps-5(RNAi)_downregulated
      [cgc5767]:cluster_8
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_ET
      [cgc5767]:expression_class_ET_max(53_min)
      [cgc5767]:expression_class_E_pi(41_min)
      [cgc5767]:expression_class_E_pi(53_min)
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_ME
      [cgc5767]:expression_class_MET
      [cgc6390]:Cluster_E
      [cgc6390]:oogenesis-enriched
    Interaction (202)
  Map_info: Map: V Position: 2.55472 Error: 0.001161
    Positive: Positive_clone: Y32F6A Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00030864
    WBPaper00036383
    WBPaper00065308
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene