WormBase Tree Display for Gene: WBGene00007504

WBGene00007504 SMap: S_parent: Sequence: C09H10
  Identity: Version: 2
    Name: CGC_name: nbs-1
      Sequence_name: C09H10.10
      Molecular_name: C09H10.10a
        C09H10.10a.1
        CE44319
        C09H10.10b
        CE43232
        C09H10.10b.1
      Other_name: CELE_C09H10.10 Accession_evidence: NDB BX284602
      Public_name: nbs-1
    DB_info: Database: AceView gene 2L386
        WormQTL gene WBGene00007504
        SignaLink protein WBGene00007504
        WormFlux gene WBGene00007504
        NDB locus_tag CELE_C09H10.10
        NCBI gene 174694
        RefSeq protein NM_063973.3
            NM_001361876.2
        TrEMBL UniProtAcc Q9U3Q2
            A0A2K5ATP9
        UniProt_GCRP UniProtAcc Q9U3Q2
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:48 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 07 Jun 2018 14:30:09 WBPerson1983 Name_change: CGC_name: nbs-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: nbs
    Allele (25)
    Strain: WBStrain00000297
      WBStrain00000298
      WBStrain00051121
    RNASeq_FPKM (74)
    Contained_in_operon: CEOP2717
    Ortholog (18)
    Structured_description: Automated_description: Enriched in germ line; germline precursor cell; intestine; and muscle cell based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including let-60; eat-2; and sek-1 based on tiling array; RNA-seq; and microarray studies. Is affected by seven chemicals including rotenone; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SMAD/FHA domain superfamily; FHA domain; and Forkhead-associated (FHA) domain. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: C09H10.10a
      C09H10.10b
    Corresponding_CDS_history (2)
    Corresponding_transcript: C09H10.10a.1
      C09H10.10b.1
    Other_sequence: CGC00691_1
      CJC17395_1
      CR05853
      CRC06501_1
    Associated_feature: WBsf989621
      WBsf223888
  Experimental_info: RNAi_result (31)
    Expr_pattern: Expr1020252
      Expr1033227
      Expr1144322
      Expr2000671
      Expr2018893
    Microarray_results (19)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00037950:AVE-neuron_L1-larva_expressed
      WBPaper00037950:bodywall-muscle_L1-larva_expressed
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:germline-precursors_embryo_enriched
      WBPaper00037950:germline-precursors_embryo_SelectivelyEnriched
      WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00040560:hpl-2_embryo_downregulated
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044656:tatn-1(qd182)_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044760:germline_specific
      WBPaper00044786:emr-1(gk119)_downregulated
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_downregulated
      WBPaper00048988:neuron_expressed
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:daf-2(e1370)_vs_daf-2(e1370);mir-34(gk437)_regulated_dauer_25C
      WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00051039:germline_enriched
      WBPaper00051404:alg-2(ok304)_upregulated
      WBPaper00051404:alg-5(ram2)_upregulated
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00053308:SMG-2_associated_NMD(-)_unaltered_ClassII
      WBPaper00053321:PGCs_enriched_NuGen
      WBPaper00055354:eat-2(ad1116)_upregulated
      WBPaper00055354:Rapamycin-Allantoin_upregulated
      WBPaper00055354:Rapamycin_upregulated
      WBPaper00055648:germline_expressed
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056293:rpl-5(0)-rpl-33(0)_upregulated
      WBPaper00056443:sek-1(km4)_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00057288:iff-1(RNAi)_upregulated_transcript
      WBPaper00058598:sin-3(tm1276)_upregulated
      WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
      WBPaper00060014:set-2(zr2012)_downregulated
      WBPaper00061007:S.aquatilis_downregulated
      WBPaper00061203:let-418(n3536)_downregulated
      WBPaper00061203:sin-3(tm1276)_downregulated
      WBPaper00061527:mrps-21-F44G4.3
      WBPaper00061527:pbs-3_18439-rpn-5
      WBPaper00064716:paraquat_upregulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065373:Cisplatin_upregulated_WT
      WBPaper00065993:glp-1(e2141)_downregulated
      WBPaper00066110:tetraploid_vs_diploid_downregulated
      cgc4489_group_3
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026980:intestine_enriched
      WBPaper00031003:24hr_muscle_enriched
      WBPaper00031003:total_muscle_enriched
      WBPaper00034739:N2moreDR1350
      WBPaper00034757:down_by_oxidative_stress
      WBPaper00035905:FBF-1_Associated
      WBPaper00036130:mir-243_down_regulated
      WBPaper00036286:Pattern_H
      WBPaper00036383:ash-2_Day8_regulated
      WBPaper00037695:LD_3-day
      WBPaper00037695:WC_CC_6-day
      WBPaper00038231:Cry5B_1.5-fold_downregulated
      WBPaper00040858:eQTL_age_regulated_aging
      WBPaper00040876:mir-35_upregulated
      WBPaper00040963:TA300_down
      WBPaper00041002:HQ_3d_0.2mM_Up
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00045263:0.1mM-paraquat_upregulated
      WBPaper00045263:isp-1(qm150)_upregulated
      WBPaper00045263:nuo-6(qm200)_upregulated
      WBPaper00045263:ProLongevity-mtROS_upregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_upregulated
      WBPaper00048989:N2_allantoin_upregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      [cgc5376]:let-60(G12V)-regulated_genes
      [cgc6390]:Cluster_B
    Interaction: WBInteraction000556903
      WBInteraction000556904
  Map_info: Map: II Position: 3.20732
    Positive: Positive_clone: C09H10 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00054279
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene