WormBase Tree Display for Gene: WBGene00007018

WBGene00007018 Evidence: Author_evidence: Bourbon H-M
  SMap: S_parent: Sequence: C55B7
  Identity (6)
  Gene_info: Biotype: SO:0001217
    Gene_class: mdt
    Allele (40)
    Legacy_information: [C.elegansII] h293 : sterile adult. OA1: h490 (similar). [KR]
    Strain: WBStrain00003323
      WBStrain00023756
    RNASeq_FPKM (74)
    GO_annotation (11)
    Contained_in_operon: CEOP1324
    Ortholog (38)
    Structured_description: Automated_description: Predicted to enable transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II and termination of RNA polymerase II transcription. Predicted to be located in nucleus. Predicted to be part of core mediator complex and mediator complex. Is an ortholog of human MED18 (mediator complex subunit 18). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: C55B7.9a
      C55B7.9b
    Corresponding_transcript: C55B7.9a.1
      C55B7.9a.2
      C55B7.9a.3
      C55B7.9b.1
    Other_sequence (47)
    Associated_feature: WBsf649241
      WBsf664342
      WBsf664343
      WBsf219596
  Experimental_info: RNAi_result (24)
    Expr_pattern: Chronogram247
      Expr1016737
      Expr1033008
      Expr1147213
      Expr2013473
      Expr2031707
    Drives_construct: WBCnstr00003794
      WBCnstr00034034
    Construct_product: WBCnstr00034034
    Microarray_results (18)
    Expression_cluster: WBPaper00029359_1280
      WBPaper00029359_1444
      WBPaper00029359_1504
      WBPaper00029359_1604
      WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00032097:CGH-1-associated-mRNA
      WBPaper00033065:cyc-1(RNAi)_downregulated
      WBPaper00038438:Harposporium_24hr_upregulated_RNAseq
      WBPaper00042194:nhr-114(RNAi)_upregulated
      WBPaper00044656:tatn-1(qd182)_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044760:germline_specific
      WBPaper00045571:germline-ablation_downregulated
      WBPaper00045774:clk-1_downregulated
      WBPaper00048988:daf-16(mu86)_upregulated_neuron
      WBPaper00048988:neuron_expressed
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00050344:AFD-neuron_enriched
      WBPaper00050344:PLM-neuron_enriched
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00051039:germline_enriched
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053289:DREAM-target
      WBPaper00053295:lin-22(ot269)_downregulated
      WBPaper00053810:daf-2(e1370)_downregulated
      WBPaper00053810:isp-1(qm150)_downregulated
      WBPaper00053810:nuo-6(qm200)_downregulated
      WBPaper00054493:hpl-2(tm1489)_downregulated
      WBPaper00055648:germline_expressed
      WBPaper00055941:atfs-1(et15)_downregulated
      WBPaper00056009:propionate_upregulated_vitamin-B12_downregulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_downregulated_N2
      WBPaper00056275:P.aeruginosa_downregulated
      WBPaper00056275:P.aeruginosa_downregulated_atf-7(qd22qd130)_dependent
      WBPaper00056284:ints-5(RNAi)_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00056809:smn-1(ok355)_downregulated
      WBPaper00056826:SGP_biased
      WBPaper00057041:unc-70(cas983)_upregulated
      WBPaper00057288:Cold_downregulated_transcript
      WBPaper00058598:mex-3(eu149)_downregulated
      WBPaper00058598:sin-3(tm1276)_upregulated
      WBPaper00058691:sin-3(tm1276)_downregulated
      WBPaper00058725:sftb-1(cer6)_downregulated
      WBPaper00058725:sftb-1(cer39)_downregulated
      WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
      WBPaper00059356:BAZ-2_SET-6_interacting
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00061203:sin-3(tm1276)_downregulated
      WBPaper00061340:Neuroblast_AFD_RMD
      WBPaper00061340:Neuroblast_IL1_IL2
      WBPaper00061340:OLQ_grandparent
      WBPaper00061340:Parent_of_AMsh_URB
      WBPaper00061527:R07E4.5-skp-1_1608
      WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
      WBPaper00062159:hda-2(ok1479)_downregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064539:nhr-114(gk849)_downregulated
      WBPaper00064716:paraquat_upregulated
      WBPaper00065086:JU1400_N.ausubeli_regulated
      WBPaper00065086:JU1400_N.ferruginous_regulated
      WBPaper00065373:sek-1(km4)_upregulated_cisplatin
      WBPaper00065373:sek-1(km4)_upregulated_Ref
      WBPaper00065975:P-body_vs_WholeAnimal_enriched
      WBPaper00065993:glp-1(e2141)_downregulated
      WBPaper00066062:xrep-4(lax137)_upregulated
      WBPaper00066085:sin-3(syb2172)_downregulated
      WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
      cgc4489_group_2
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00031252:AIN-1_IP_enriched
      WBPaper00036130:mir-243_down_regulated
      WBPaper00036286:Pattern_H
      WBPaper00038231:Cry5B_1.5-fold_downregulated
      WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.2
      WBPaper00041002:HF_3d_2.0mM_Up
      WBPaper00041002:HF_11d_2.0mM_Down
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041906:I-3690_vs_OP50_3d
      WBPaper00045263:0.1mM-paraquat_upregulated
      WBPaper00048989:N2_allantoin_upregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_E_pi(41_min)
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_ME
      [cgc6390]:Cluster_E
      [cgc6390]:oogenesis-enriched
    Interaction (71)
  Map_info: Map: I Position: 1.15876 Error: 0.001438
    Positive: Positive_clone: C55B7 Inferred_automatically: From sequence, transcript, pseudogene data
        F37E3
        K06A5
        R10A10
        T23H2
    Mapping_data: 2_point: 5231
        5230
      Pos_neg_data (14)
    Pseudo_map_position
  Reference (14)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
    Locus positive method : stable transformation rescue [Clucas C][021125 ck1]
    Locus complementation data : Cosmid mix R10A10, F37E3, T23H2, K06A5 and C55B7 rescues let-604. Injections performed on dpy-5(e61)let-604(h293)unc-13(e450)/+ strain and analysed for fertile DpyUncs [Clucas C][021125 ck1]
    Postitive method is stable transformation rescue
  Method: Gene