WormBase Tree Display for Gene: WBGene00006673
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| WBGene00006673 | SMap | S_parent | Sequence | C40C9 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | twk-20 | Person_evidence | WBPerson655 | |||||
| Sequence_name | C40C9.1 | ||||||||
| Molecular_name | C40C9.1 | ||||||||
| C40C9.1.1 | |||||||||
| CE24839 | |||||||||
| Other_name | CELE_C40C9.1 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | twk-20 | ||||||||
| DB_info | Database | AceView | gene | XO261 | |||||
| WormQTL | gene | WBGene00006673 | |||||||
| WormFlux | gene | WBGene00006673 | |||||||
| NDB | locus_tag | CELE_C40C9.1 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00006673|UniProtKB=G5ECW6 | |||||||
| family | PTHR11003 | ||||||||
| NCBI | gene | 181485 | |||||||
| RefSeq | protein | NM_077883.2 | |||||||
| TrEMBL | UniProtAcc | G5ECW6 | |||||||
| UniProt_GCRP | UniProtAcc | G5ECW6 | |||||||
| OMIM | gene | 603220 | |||||||
| 605874 | |||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:41 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | twk | ||||||||
| Allele (50) | |||||||||
| Legacy_information | [Thomas JH] twk for potassium channel family, type Twik (double P domain). Predicted gene ZK1067.5 | ||||||||
| [Thomas JH] twk for potassium channel family, type Twik (double P domain). Predicted gene C40C9.1 | |||||||||
| Strain | WBStrain00026426 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (15) | |||||||||
| Ortholog (32) | |||||||||
| Paralog (47) | |||||||||
| Structured_description | Automated_description | Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. Expressed in muscle cell and neurons. Human ortholog(s) of this gene implicated in Birk-Barel syndrome and primary pulmonary hypertension. Is an ortholog of human KCNK3 (potassium two pore domain channel subfamily K member 3) and KCNK9 (potassium two pore domain channel subfamily K member 9). | Paper_evidence | WBPaper00065943 | |||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:14557 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6278) | ||||
| DOID:0050675 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6283) | ||||||
| Molecular_info | Corresponding_CDS | C40C9.1 | |||||||
| Corresponding_transcript | C40C9.1.1 | ||||||||
| Other_sequence | SS02538 | ||||||||
| JI246191.1 | |||||||||
| SSC05256_1 | |||||||||
| Associated_feature | WBsf717391 | ||||||||
| WBsf1007674 | |||||||||
| WBsf1007675 | |||||||||
| WBsf1024267 | |||||||||
| WBsf1024268 | |||||||||
| WBsf236596 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00027783 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00042248 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1370 | ||||||||
| Expr1012496 | |||||||||
| Expr1146239 | |||||||||
| Expr2017647 | |||||||||
| Expr2035787 | |||||||||
| Drives_construct | WBCnstr00010244 | ||||||||
| WBCnstr00034224 | |||||||||
| Construct_product | WBCnstr00010244 | ||||||||
| WBCnstr00034224 | |||||||||
| Microarray_results (18) | |||||||||
| Expression_cluster | WBPaper00037950:all-neurons_L2-larva_expressed | ||||||||
| WBPaper00037950:GABAergic-motor-neurons_embryo_enriched | |||||||||
| WBPaper00037950:intestine_L2-larva_expressed | |||||||||
| WBPaper00038438:E.faecalis_24hr_upregulated_RNAseq | |||||||||
| WBPaper00038438:Harposporium_24hr_upregulated_RNAseq | |||||||||
| WBPaper00038438:P.lumniescens_24hr_upregulated_RNAseq | |||||||||
| WBPaper00045420:fertilization_downregulated_transcript | |||||||||
| WBPaper00050488:adult_vs_dauer_regulated_N2_20C | |||||||||
| WBPaper00055103:thoc-5(wy822)_upregulated | |||||||||
| WBPaper00055354:eat-2(ad1116)_downregulated | |||||||||
| WBPaper00055354:Rapamycin-Psora-Allantoin_downregulated | |||||||||
| WBPaper00055354:Rapamycin-Rifampicin-Psora_downregulated | |||||||||
| WBPaper00055354:Rifampicin-Psora_downregulated | |||||||||
| WBPaper00058598:mex-1(or286)_upregulated | |||||||||
| WBPaper00058598:spn-4(tm291)_upregulated | |||||||||
| WBPaper00061527:sre-33-ZK1025.1_8337 | |||||||||
| WBPaper00061653:alh-4(hj221)_upregulated | |||||||||
| WBPaper00061753:csr-1(tor159)_upregulated_25C | |||||||||
| WBPaper00062103:neuron_enriched | |||||||||
| WBPaper00062159:hda-2(ok1479)_upregulated | |||||||||
| WBPaper00062325:muscle_enriched_coding-RNA | |||||||||
| WBPaper00062672:let-418(n3536)dcp-66(RNAi)_upregulated | |||||||||
| WBPaper00065315:mating_downregulated_Day2-7 | |||||||||
| WBPaper00066110:Doxorubicin_upregulated_tetraploid | |||||||||
| WBPaper00025141:N2_Expressed_Genes | |||||||||
| WBPaper00026929:sir-2.1_overexpression_regulated | |||||||||
| WBPaper00031003:hlh_1_enriched | |||||||||
| WBPaper00037113:Diazinon_16C_regulated | |||||||||
| WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.2 | |||||||||
| Interaction (11) | |||||||||
| Map_info | Map | X | Position | 14.0098 | Error | 0.006152 | |||
| Positive | Positive_clone | C40C9 | Person_evidence | WBPerson654 | |||||
| WBPerson655 | |||||||||
| Inferred_automatically | From sequence, transcript, pseudogene data | ||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00026748 | ||||||||
| WBPaper00038487 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00055090 | |||||||||
| Remark | twk-20 was connected to ZK1067.5 | CGC_data_submission | |||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
