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WormBase Tree Display for Gene: WBGene00004091

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Name Class

WBGene00004091EvidenceAuthor_evidenceBergeron KF
SMapS_parentSequenceT14G10
IdentityVersion1
NameCGC_namepps-1
Sequence_nameT14G10.1
Molecular_nameT14G10.1a
T14G10.1a.1
CE06447
T14G10.1b
CE49754
T14G10.1b.1
Other_nameCELE_T14G10.1Accession_evidenceNDBBX284604
Public_namepps-1
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:34WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classpps
Allele (36)
StrainWBStrain00036362
WBStrain00007579
RNASeq_FPKM (74)
GO_annotation (21)
Contained_in_operonCEOP4619
Ortholog (47)
Structured_descriptionConcise_descriptionpps-1 is orthologous to human PAPSS1 (OMIM:603262) and human PAPSS2 (OMIM:603005, mutated in spondyloepimetaphyseal dysplasia).Curator_confirmedWBPerson1823
WBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable adenylylsulfate kinase activity. Predicted to be involved in 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process and sulfate assimilation. Predicted to be located in nucleus. Expressed in epithelial cell and pharyngeal gland cell. Human ortholog(s) of this gene implicated in spondyloepimetaphyseal dysplasia, Pakistani type. Is an ortholog of human PAPSS1 (3'-phosphoadenosine 5'-phosphosulfate synthase 1) and PAPSS2 (3'-phosphoadenosine 5'-phosphosulfate synthase 2).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0050812Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:8604)
Molecular_infoCorresponding_CDST14G10.1a
T14G10.1b
Corresponding_transcriptT14G10.1a.1
T14G10.1b.1
Other_sequence (83)
Associated_feature (5)
Experimental_infoRNAi_resultWBRNAi00115318Inferred_automaticallyRNAi_primary
WBRNAi00053330Inferred_automaticallyRNAi_primary
WBRNAi00035569Inferred_automaticallyRNAi_primary
WBRNAi00070597Inferred_automaticallyRNAi_primary
WBRNAi00070596Inferred_automaticallyRNAi_primary
Expr_patternChronogram1959
Expr4395
Expr4396
Expr6696
Expr1016543
Expr1031975
Expr1156916
Expr2015021
Expr2033256
Drives_constructWBCnstr00002978
WBCnstr00011963
WBCnstr00011964
WBCnstr00035705
Construct_productWBCnstr00011964
WBCnstr00035705
Microarray_results (21)
Expression_clusterWBPaper00031040:TGF-beta_adult_downregulated
WBPaper00037950:all-neurons_L2-larva_expressed
WBPaper00037950:AVA-neuron_L1-larva_expressed
WBPaper00037950:AVE-neuron_L1-larva_expressed
WBPaper00037950:BAG-neuron_blastula-embryo_expressed
WBPaper00037950:bodywall-muscle_L2-larva_expressed
WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
WBPaper00037950:coelomocytes_L2-larva_expressed
WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
WBPaper00037950:germline-precursors_blastula-embryo_expressed
WBPaper00037950:hypodermis_L3-L4-larva_expressed
WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
WBPaper00041072:UTX-1_interacting_protein
WBPaper00041954:ethanol_upregulated
WBPaper00042477:rsr-2(RNAi)_downregulated_RNAseq
WBPaper00044501:gld-1_let-7_regulated
WBPaper00044736:oscillating_dev_expression
WBPaper00045521:Gender_Neutral
WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
WBPaper00048923:Aging_regulated
WBPaper00048988:neuron_expressed
WBPaper00049489:AMsh-glia_enriched
WBPaper00049545:cco-1(RNAi)_downregulated
WBPaper00049545:jmjd-3.1(+)_downregulated
WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
WBPaper00049942:hsf-1(RNAi)_downregulated
WBPaper00050344:AFD-neuron_enriched
WBPaper00050344:PLM-neuron_enriched
WBPaper00050370:dpy-21(e428)_L3_downregulated
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050726:OsmoticStress_regulated_Food
WBPaper00050801:DAF-12_dauer_regulome
WBPaper00050801:DAF-16_dauer_regulome
WBPaper00050990:GABAergic-neuron_expressed
WBPaper00050990:hypodermis_expressed
WBPaper00050990:intestine_expressed
WBPaper00050990:seam_expressed
WBPaper00051245:epidermis_cytoplasm_expressed
WBPaper00051245:epidermis_nucleus_expressed
WBPaper00051245:intestine_cytoplasm_expressed
WBPaper00051245:nucleus_specific
WBPaper00052884:emb-4(hc60)_downregulated
WBPaper00053302:stavudine_72h_regulated
WBPaper00053302:zidovudine_72h_regulated
WBPaper00053388:dauer_regulated_Cluster5
WBPaper00053599:oocyte_vs_mitosis_downregulated
WBPaper00053810:daf-2(e1370)_downregulated
WBPaper00053810:nuo-6(qm200)_downregulated
WBPaper00055354:Rapamycin-Metformin_upregulated
WBPaper00055648:germline_expressed
WBPaper00056034:pals-22(jy3)_downregulated
WBPaper00056290:hsp-6(mg585)_upregulated
WBPaper00056443:sek-1(km4)_downregulated
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
WBPaper00056826:hmc_biased
WBPaper00057068:ints-4(RNAi)_downregulated_Cadmium
WBPaper00057288:Cold_upregulated_transcript
WBPaper00058691:sin-3(tm1276)_downregulated
WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
WBPaper00059763:neuron_expressed
WBPaper00060014:set-2(zr2012)_upregulated
WBPaper00060683:hlh-11(ko1)_downregulated
WBPaper00061340:ASJ
WBPaper00061340:Neuroblast_ASJ_AUA
WBPaper00061527:F31C3.4_6048-cutc-1_15804
WBPaper00061651:ASJ_enriched
WBPaper00062159:hda-2(ok1479)_upregulated
WBPaper00062193:hsf-1(RNAi)_downregulated
WBPaper00064505:tamoxifen_upregulated
WBPaper00064539:nhr-114(gk849)_downregulated
WBPaper00064716:paraquat_upregulated
WBPaper00065258:anchor-cell_enriched
WBPaper00065373:Cisplatin_downregulated_WT
WBPaper00065373:sek-1(km4)_downregulated_Ref
WBPaper00065841:45_0
WBPaper00065841:78_0
WBPaper00065841:99_0
WBPaper00065975:P-body_vs_WholeAnimal_enriched
WBPaper00066085:sin-3(tm1276)_downregulated
cgc4489_group_3
WBPaper00025032:cluster_1
WBPaper00025141:N2_Expressed_Genes
WBPaper00025141:unc-4::GFP_Expressed_Genes
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00026952:class_E
WBPaper00026980:intestine_enriched
WBPaper00030839:Larval_Pan_Neuronal
WBPaper00032948:FedUp
WBPaper00032948:MoltOssilate
WBPaper00035588:alg-1(-)_upregulated
WBPaper00035905:FBF-1_Associated
WBPaper00036123:Cadmium_regulated
WBPaper00037611:RNP-8-associated
WBPaper00037901:GLD-1_mRNA_targets
WBPaper00038172:crh-1null_down_regulated
WBPaper00040185:nhr-23(RNAi)_downregulated
WBPaper00040858:eQTL_age_regulated_developing
WBPaper00040858:eQTL_regulated_developing
WBPaper00041606:CE_S.marcescens_regulated
WBPaper00041606:CE_X.nematophila_regulated
WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
WBPaper00047070:N2_UV_downregulated
WBPaper00047070:xpa-1_UV_downregulated
WBPaper00048624:hlh-25(ok1710)_upregulated
WBPaper00048989:N2_rapamycin_downregulated
WBPaper00053236:Starvation_regulated_GR1307
WBPaper00053236:Starvation_regulated_N2
[cgc5767]:cluster_1
[cgc5767]:expression_class_M
[cgc5767]:expression_class_MD
[cgc5767]:expression_class_MD_pd(23_min)
[cgc5767]:expression_class_SM
[cgc5767]:expression_class_SMD
Interaction (40)
Map_infoMapIVPosition4.5514Error0.001015
PositivePositive_cloneT14G10Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point5525
4743
5002
Pseudo_map_position
ReferenceWBPaper00027123
WBPaper00027857
WBPaper00031295
WBPaper00033574
WBPaper00035539
WBPaper00038491
WBPaper00040922
WBPaper00045573
WBPaper00055090
WBPaper00065026
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene