WormBase Tree Display for Gene: WBGene00003335
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WBGene00003335 | Evidence | Paper_evidence | WBPaper00005825 | ||||||
---|---|---|---|---|---|---|---|---|---|
SMap | S_parent | Sequence | F56A12 | ||||||
Identity | Version | 1 | |||||||
Name | CGC_name | mir-241 | Person_evidence | WBPerson18 | |||||
Sequence_name | F56A12.4 | ||||||||
Molecular_name | F56A12.4 | ||||||||
F56A12.4a | |||||||||
F56A12.4b | |||||||||
Other_name | cel-mir-241 | Remark | miRBase V21 import | ||||||
Cel-Let-7-P8 | Remark | MirGeneDB 2.1 import | |||||||
CELE_F56A12.4 | Accession_evidence | NDB | BX284605 | ||||||
Public_name | mir-241 | ||||||||
DB_info | Database | miRBase | acc | MI0000317 | |||||
SignaLink | mirna | cel-mir-241 | |||||||
MirGeneDB | cel | Cel-Let-7-P8 | |||||||
NDB | locus_tag | CELE_F56A12.4 | |||||||
NCBI | gene | 3565950 | |||||||
RefSeq | protein | NR_002403.2 | |||||||
RNAcentral | URSid | URS00002BFC83 | |||||||
URS000040AE62 | |||||||||
URS000040F239 | |||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:31 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001265 | |||||||
Gene_class | mir | ||||||||
Allele (11) | |||||||||
Strain | WBStrain00027442 | ||||||||
WBStrain00027449 | |||||||||
WBStrain00027441 | |||||||||
WBStrain00040223 | |||||||||
WBStrain00040225 | |||||||||
WBStrain00040228 | |||||||||
WBStrain00051617 | |||||||||
In_cluster | LET-7 | ||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation | 00106260 | ||||||||
00106261 | |||||||||
Structured_description | Concise_description | mir-241 encodes a microRNA, a small non-protein coding RNA and appears to have a potential ortholog in C. briggsae; based on RNA sequence identity, miR-241 belongs to the let-7 family of microRNAs along with C. elegans miR-48 and miR-84 and human let-7, miR-196-1 and miR-196-2; mir-241 acts redundantly with miR-48 and mir-84 to control L2 to L3 larval and larval to adult stage transitions; miR-241 is strongly expressed from the L3 larval stage into the adult stage in normal worms and in glp-4(bn2) mutant worms. | Paper_evidence | WBPaper00005825 | |||||
WBPaper00010853 | |||||||||
Curator_confirmed | WBPerson324 | ||||||||
Date_last_updated | 08 Feb 2005 00:00:00 | ||||||||
Automated_description | Involved in miRNA-mediated gene silencing by inhibition of translation and positive regulation of development, heterochronic. Expressed in body wall musculature; excretory canal; hermaphrodite distal tip cell; and touch receptor neurons. Used to study Parkinson's disease. | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Experimental_model | DOID:14330 | Homo sapiens | Paper_evidence | WBPaper00035654 | ||||
Curator_confirmed | WBPerson324 | ||||||||
Date_last_updated | 06 Jan 2014 00:00:00 | ||||||||
Disease_relevance | mir-241 is a small non-protein coding RNA that belongs to the let-7 family; microRNA expression profiling studies indicate that mir-241 is overexpressed in an elegans Parkinson''s disease model, the pdr-1 mutant (pdr-1 is orthologous to human PARKIN). | Homo sapiens | Paper_evidence | WBPaper00035654 | |||||
Curator_confirmed | WBPerson324 | ||||||||
Date_last_updated | 06 Jan 2014 00:00:00 | ||||||||
Models_disease_in_annotation | WBDOannot00000268 | ||||||||
Molecular_info | Corresponding_transcript | F56A12.4 | |||||||
F56A12.4a | |||||||||
F56A12.4b | |||||||||
Associated_feature (10) | |||||||||
Experimental_info | Expr_pattern (11) | ||||||||
Drives_construct | WBCnstr00005522 | ||||||||
WBCnstr00011651 | |||||||||
WBCnstr00015774 | |||||||||
WBCnstr00015775 | |||||||||
WBCnstr00017833 | |||||||||
Construct_product | WBCnstr00015775 | ||||||||
Expression_cluster | WBPaper00040221:DAF-12_target_ALF4 | ||||||||
WBPaper00040221:DAF-12_target_ALF9 | |||||||||
WBPaper00042480:20mM_nicotine_upregulated | |||||||||
WBPaper00045316:miRNA_N2_L1_vs_embryo_downregulated_adult | |||||||||
WBPaper00045316:miRNA_N2_L2_vs_L1_upregulated_adult | |||||||||
WBPaper00045316:miRNA_N2_L3_vs_L2_upregulated_adult | |||||||||
WBPaper00045316:miRNA_prg-1_downregulated_adult | |||||||||
WBPaper00045316:miRNA_prg-1_downregulated_embryo | |||||||||
WBPaper00045316:miRNA_prg-1_downregulated_L3 | |||||||||
WBPaper00045316:miRNA_prg-1_downregulated_L4 | |||||||||
WBPaper00045316:miRNA_prg-1_L1_vs_embryo_upregulated_adult | |||||||||
WBPaper00045316:miRNA_prg-1_L2_vs_L1_upregulated_adult | |||||||||
WBPaper00045316:miRNA_prg-1_L3_vs_L2_upregulated_adult | |||||||||
WBPaper00045316:miRNA_prg-1_L4_vs_L3_upregulated_adult | |||||||||
WBPaper00045316:miRNA_prg-1_upregulated_adult | |||||||||
WBPaper00045316:miRNA_prg-1_upregulated_L1 | |||||||||
WBPaper00045316:miRNA_prg-1_upregulated_L2 | |||||||||
WBPaper00045316:miRNA_prg-1_upregulated_L4 | |||||||||
WBPaper00046156:eat-2(ad1116)_Day1_upregulated | |||||||||
WBPaper00046156:eat-2(ad1116)_Day8_downregulated | |||||||||
WBPaper00046303:P.aeruginosa_upregulated_miRNA | |||||||||
WBPaper00051404:alg-1(gk214)_downregulated_miRNA | |||||||||
WBPaper00051404:alg-1(gk214)_upregulated_miRNA | |||||||||
WBPaper00051404:alg-2(ok304)_downregulated_miRNA | |||||||||
WBPaper00051404:alg-2(ok304)_upregulated_miRNA | |||||||||
WBPaper00051404:alg-5(ram2)_downregulated_miRNA | |||||||||
WBPaper00051404:alg-5(ram2)_upregulated_miRNA | |||||||||
WBPaper00051404:alg-5(tm1163)_upregulated_miRNA | |||||||||
WBPaper00053318:Aging_downregulated_miRNA_N2 | |||||||||
WBPaper00053318:mir-71(n4115)_upregulated_miRNA | |||||||||
WBPaper00056284:ints-5(RNAi)_upregulated | |||||||||
WBPaper00056809:smn-1(ok355)_upregulated | |||||||||
WBPaper00056868:P.aeruginosa_upregulated_smallRNA | |||||||||
WBPaper00057033:pry-1(mu38)_upregulated | |||||||||
WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA | |||||||||
WBPaper00060100:SiNP_upregulated_miRNA | |||||||||
WBPaper00062103:neuron_enriched | |||||||||
WBPaper00064661:lpd-3(ok2138)_upregulated | |||||||||
Interaction (17) | |||||||||
WBProcess | WBbiopr:00000083 | ||||||||
Map_info | Map | V | Position | 6.27847 | Error | 0.001234 | |||
Positive | Inside_rearr | nDf51 | |||||||
Positive_clone | F56A12 | Inferred_automatically | From CDS info | ||||||
From sequence, transcript, pseudogene data | |||||||||
Mapping_data | Multi_point | 5653 | |||||||
Pos_neg_data | 10750 | ||||||||
Pseudo_map_position | |||||||||
Reference (52) | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |