| WBGene00001715 | Evidence | Paper_evidence | WBPaper00003717 |
|---|
| SMap | S_parent | Sequence | K10C2 |
| Identity | Version | 1 |
| | Name | CGC_name | grl-6 | Person_evidence | WBPerson83 |
| | | Sequence_name | K10C2.5 |
| | | Molecular_name | K10C2.5 |
| | | | K10C2.5.1 |
| | | | CE04751 |
| | | Other_name | CELE_K10C2.5 | Accession_evidence | NDB | BX284606 |
| | | Public_name | grl-6 |
| | DB_info | Database | AceView | gene | XH68 |
| | | | WormQTL | gene | WBGene00001715 |
| | | | WormFlux | gene | WBGene00001715 |
| | | | NDB | locus_tag | CELE_K10C2.5 |
| | | | Panther | gene | CAEEL|WormBase=WBGene00001715|UniProtKB=Q94273 |
| | | | | family | PTHR23261 |
| | | | NCBI | gene | 187253 |
| | | | RefSeq | protein | NM_076683.2 |
| | | | TREEFAM | TREEFAM_ID | TF315611 |
| | | | TrEMBL | UniProtAcc | Q94273 |
| | | | UniProt_GCRP | UniProtAcc | Q94273 |
| | Species | Caenorhabditis elegans |
| | History | Version_change | 1 | 07 Apr 2004 11:29:25 | WBPerson1971 | Event | Imported | Initial conversion from geneace |
| | Status | Live |
| Gene_info | Biotype | SO:0001217 |
| | Gene_class | grl |
| | Allele (27) |
| | Strain | WBStrain00032691 |
| | RNASeq_FPKM (74) |
| | Ortholog (17) |
| | Paralog (32) |
| | Structured_description | Concise_description | grl-6 encodes a hedgehog-like protein, with an N-terminal signalsequence, a central proline-rich low-complexity region, and a C-terminalGround-like (Grl) domain; GRL-6 is expressed in larval intestine, amphidsocket cells, and neurons; the Grl domain is predicted to form acysteine-crosslinked protein involved in intercellular signalling, andit has subtle similarity to the N-terminal Hedge domain of HEDGEHOGproteins. | Paper_evidence | WBPaper00003717 |
| | | | | | WBPaper00006525 |
| | | | | | WBPaper00026841 |
| | | | | | WBPaper00027263 |
| | | | | Curator_confirmed | WBPerson567 |
| | | | | Date_last_updated | 05 Nov 2006 00:00:00 |
| | | Automated_description | Expressed in PVT. Is predicted to encode a protein with the following domain: Ground-like domain. | Paper_evidence | WBPaper00065943 |
| | | | | Curator_confirmed | WBPerson324 |
| | | | | | WBPerson37462 |
| | | | | Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase |
| | | | | Date_last_updated | 29 Nov 2023 00:00:00 |
| Molecular_info | Corresponding_CDS | K10C2.5 |
| | Corresponding_transcript | K10C2.5.1 |
| | Other_sequence | CSC01471_1 |
| | | FD516716.1 |
| | | AS14466 |
| | | FC811116.1 |
| | | MC00143 |
| | Associated_feature | WBsf654069 |
| | | WBsf670630 |
| Experimental_info | RNAi_result | WBRNAi00050495 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00016961 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00034239 | Inferred_automatically | RNAi_primary |
| | Expr_pattern | Expr4445 |
| | | Expr6380 |
| | | Expr1019060 |
| | | Expr1154205 |
| | | Expr2012271 |
| | | Expr2030507 |
| | Drives_construct | WBCnstr00003018 |
| | | WBCnstr00012009 |
| | | WBCnstr00036745 |
| | Construct_product | WBCnstr00036745 |
| | Microarray_results (19) |
| | Expression_cluster | WBPaper00033070:Elbe_downregulated |
| | | WBPaper00038168:lin-15B(n744)_downregulated |
| | | WBPaper00038168:lin-15B(n744)_upregulated |
| | | WBPaper00038438:D.coniospora_12hr_upregulated_RNAseq |
| | | WBPaper00038438:E.faecalis_24hr_upregulated_RNAseq |
| | | WBPaper00038438:Harposporium_24hr_upregulated_RNAseq |
| | | WBPaper00038438:P.lumniescens_24hr_upregulated_RNAseq |
| | | WBPaper00040560:hpl-2_L3_downregulated |
| | | WBPaper00044736:oscillating_dev_expression |
| | | WBPaper00045316:prg-1_upregulated_L2 |
| | | WBPaper00045390:tunicamycin_downregulated |
| | | WBPaper00045417:128Q-huntingtin_downreglated |
| | | WBPaper00045774:clk-1_upregulated |
| | | WBPaper00046024:sleep_upregulated_oscillating |
| | | WBPaper00049545:jmjd-3.1(+)_upregulated |
| | | WBPaper00049545:sur-5p-jmjd-1.2(+)_upregulated |
| | | WBPaper00050163:chd-3(eh4);let-418(RNAi)_upregulated_24-cell-embryo |
| | | WBPaper00050163:chd-3(eh4);let-418(RNAi)_upregulated_100-cell-embryo |
| | | WBPaper00050712:RC301_vs_DA650_4h-PA_upregulated |
| | | WBPaper00050801:DAF-12_dauer_regulome |
| | | WBPaper00050801:DAF-16_dauer_regulome |
| | | WBPaper00050801:DPY-21_dauer_regulome |
| | | WBPaper00053302:stavudine_24h_regulated |
| | | WBPaper00053302:zidovudine_72h_regulated |
| | | WBPaper00053771:down_by_skn-1(RNAi)_at_dpy-7(e88) |
| | | WBPaper00053771:up_at_dpy-7(e88) |
| | | WBPaper00054493:hpl-2(tm1489)_upregulated |
| | | WBPaper00055013:spt-16(RNAi)_upregulated |
| | | WBPaper00055103:thoc-5(wy822)_upregulated |
| | | WBPaper00055354:Rapamycin-Metformin_upregulated |
| | | WBPaper00055354:Rifampicin-Allantoin_upregulated |
| | | WBPaper00055626:pry-1(mu38)_downregulated |
| | | WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047) |
| | | WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated |
| | | WBPaper00056997:NMAD-1_interacting |
| | | WBPaper00057041:unc-70(cas983)_upregulated |
| | | WBPaper00058598:mex-1(or286)_downregulated |
| | | WBPaper00058691:cfp-1(tm6369)_upregulated |
| | | WBPaper00058725:sftb-1(cer6)_downregulated |
| | | WBPaper00058886:anp-1(ok608)_upregulated |
| | | WBPaper00059117:B.subtilis_upregulated |
| | | WBPaper00059421:daf-1(m40)_upregulated |
| | | WBPaper00059421:daf-3(mgDf90)_downregulated |
| | | WBPaper00059566:wdr-23(mac32)_upregulated |
| | | WBPaper00060014:set-2(tm1630)_downregulated |
| | | WBPaper00060100:SiNP_upregulated_mRNA |
| | | WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi) |
| | | WBPaper00060434:pH4.33_vs_pH6.33_uprgulated |
| | | WBPaper00060445:nfki-1(cer1)_downregulated_L1 |
| | | WBPaper00060886:met-2(n4256)_downregulated |
| | | WBPaper00060886:spr-5(by101);met-2(n4256)_downregulated |
| | | WBPaper00061340:DVC_parent |
| | | WBPaper00061340:hyp1_hyp2 |
| | | WBPaper00061527:col-128-cdh-10_9234 |
| | | WBPaper00062156:jmjd-5(zr1234)_upregulated |
| | | WBPaper00062159:hda-2(ok1479)_upregulated |
| | | WBPaper00062325:muscle_depleted_coding-RNA |
| | | WBPaper00062446:nhr-8(hd117)_upregulated |
| | | WBPaper00064005:starvation_downregulated_aptf-1(gk794)_mRNA |
| | | WBPaper00064005:starvation_downregulated_N2_mRNA |
| | | WBPaper00064107:lin-35(n745)_downregulated |
| | | WBPaper00064306:Agaro-oligosaccharides_upregulated |
| | | WBPaper00064661:lpd-3(ok2138)_upregulated |
| | | WBPaper00065158:25C_vs_15C_upregulated_WholeAnimal |
| | | WBPaper00065288:mdt-15(tm2182)_downregulated |
| | | WBPaper00065560:E.coli-HB101_downregulated_F3 |
| | | WBPaper00065746:eat-2(ad1113)_downregulated |
| | | WBPaper00065926:pgph-2(overepxreesion)_upregulated_glucose |
| | | WBPaper00065993:glp-1(e2141)_downregulated |
| | | WBPaper00066062:xrep-4(lax137)_upregulated |
| | | WBPaper00066110:tetraploid_vs_diploid_upregulated |
| | | cgc4489_group_20 |
| | | WBPaper00025141:N2_Expressed_Genes |
| | | WBPaper00032948:FedUp |
| | | WBPaper00036123:Atrazine_regulated |
| | | WBPaper00036130:mir-243_up_regulated |
| | | WBPaper00036286:Pattern_G |
| | | WBPaper00040858:eQTL_age_regulated_developing |
| | | WBPaper00040858:eQTL_regulated_developing |
| | | WBPaper00040858:eQTL_regulated_juvenile |
| | | WBPaper00040876:mir-35_downregulated |
| | | WBPaper00041939:control_vs_EtBr-exposed_48h |
| | | WBPaper00041939:control_vs_UVC-EtBr-exposed_48h |
| | | WBPaper00041939:control_vs_UVC-EtBr-exposed_51h |
| | | WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h |
| | | WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h |
| | | WBPaper00042274:tbx-2(bx59)_upregulated |
| | | WBPaper00045015:acs-3(ft5)_upregulated |
| | | WBPaper00045960:L1-L4-lethargus_upregulated |
| | | WBPaper00045960:L4-lethargus_upregulated |
| | | WBPaper00047070:xpa-1_UV_downregulated |
| | | [cgc6390]:Cluster_C |
| | Interaction | WBInteraction000305397 |
| | | WBInteraction000378475 |
| | | WBInteraction000451390 |
| | | WBInteraction000562802 |
| Map_info | Map | X | Position | -2.90361 | Error | 0.002849 |
| | Positive | Positive_clone | K10C2 | Inferred_automatically | From CDS info |
| | | | | | From sequence, transcript, pseudogene data |
| | Pseudo_map_position |
| Reference | WBPaper00003717 |
| | WBPaper00028754 |
| | WBPaper00031588 |
| | WBPaper00063946 |
| | WBPaper00064105 |
| Remark | ground-like gene, contains ground-like domain, hedgehog-related | Paper_evidence | WBPaper00003717 |
| | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission |
| Method | Gene |
